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Oxford Centre for Integrative Systems Biology
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top-articles
Oxford Centre for Integrative Systems Biology
86
(top 1%)
papers
8.0K
(top 1%)
citations
45
(top 1%)
h
-index
84
(top 1%)
g
-index
91
all documents
8.8K
doc citations
1.6K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
The ecology of the microbiome: Networks, competition, and stability
Science
2015
1,618
2
Design principles of biochemical oscillators
Nature Reviews Molecular Cell Biology
2008
970
3
Signal processing in complex chemotaxis pathways
Nature Reviews Microbiology
2011
366
4
Inhibition of 2-oxoglutarate dependent oxygenases
Chemical Society Reviews
2011
336
5
Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer
Proceedings of the National Academy of Sciences of the United States of America
2007
253
6
Inherent noise can facilitate coherence in collective swarm motion
Proceedings of the National Academy of Sciences of the United States of America
2009
240
7
Inhibitor Scaffolds for 2-Oxoglutarate-Dependent Histone Lysine Demethylases
Journal of Medicinal Chemistry
2008
221
8
Two-Component Systems and Their Co-Option for Eukaryotic Signal Transduction
Current Biology
2011
202
9
Regulation of APC/C Activity in Oocytes by a Bub1-Dependent Spindle Assembly Checkpoint
Current Biology
2009
194
10
Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors
PLoS ONE
2010
194
11
Irreversible cell-cycle transitions are due to systems-level feedback
Nature Cell Biology
2007
178
12
Conformational Spread as a Mechanism for Cooperativity in the Bacterial Flagellar Switch
Science
2010
176
13
PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase
Human Molecular Genetics
2010
153
14
Multiscale Modelling of Vascular Tumour Growth in 3D: The Roles of Domain Size and Boundary Conditions
PLoS ONE
2011
150
15
Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches
Journal of Medicinal Chemistry
2010
146
16
Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family
Journal of Biological Chemistry
2011
143
17
Spatial organization in bacterial chemotaxis
EMBO Journal
2010
135
18
Revisiting Date and Party Hubs: Novel Approaches to Role Assignment in Protein Interaction Networks
PLoS Computational Biology
2010
128
19
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
Nature Communications
2016
109
20
Multi-Cellular Rosettes in the Mouse Visceral Endoderm Facilitate the Ordered Migration of Anterior Visceral Endoderm Cells
PLoS Biology
2012
105
21
Mucin Biopolymers Prevent Bacterial Aggregation by Retaining Cells in the Free-Swimming State
Current Biology
2012
103
22
The Influence of Catalysis on Mad2 Activation Dynamics
PLoS Biology
2009
97
23
Switches and latches: a biochemical tug-of-war between the kinases and phosphatases that control mitosis
Philosophical Transactions of the Royal Society B: Biological Sciences
2011
95
24
Meiotic Prophase Requires Proteolysis of M Phase Regulators Mediated by the Meiosis-Specific APC/CAma1
Cell
2012
93
25
ParA-like protein uses nonspecific chromosomal DNA binding to partition protein complexes
Proceedings of the National Academy of Sciences of the United States of America
2012
92
26
Irreversibility of mitotic exit is the consequence of systems-level feedback
Nature
2009
91
27
Stability analysis of non-autonomous reaction-diffusion systems: the effects of growing domains
Journal of Mathematical Biology
2010
89
28
Inducible-Expression Plasmid for
Rhodobacter sphaeroides
and
Paracoccus denitrificans
Applied and Environmental Microbiology
2009
88
29
A miniaturized screen for inhibitors of Jumonji histone demethylases
Molecular BioSystems
2010
84
30
Temporal evolution of financial-market correlations
Physical Review E
2011
82
31
Structural and Mechanistic Studies on γ-Butyrobetaine Hydroxylase
Chemistry and Biology
2010
78
32
Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(ii)
Chemical Communications
2009
77
33
Kinetic Rationale for Selectivity toward N- and C-terminal Oxygen-dependent Degradation Domain Substrates Mediated by a Loop Region of Hypoxia-Inducible Factor Prolyl Hydroxylases
Journal of Biological Chemistry
2008
72
34
Polarity of bacterial magnetotaxis is controlled by aerotaxis through a common sensory pathway
Nature Communications
2014
72
35
Generalized methods and solvers for noise removal from piecewise constant signals. I. Background theory
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
2011
69
36
Factor‐inhibiting hypoxia‐inducible factor (FIH) catalyses the post‐translational hydroxylation of histidinyl residues within ankyrin repeat domains
FEBS Journal
2011
68
37
Deciphering chemotaxis pathways using cross species comparisons
BMC Systems Biology
2010
66
38
The Role of Flexibility and Conformational Selection in the Binding Promiscuity of PDZ Domains
PLoS Computational Biology
2012
65
39
Kinetochore–microtubule error correction is driven by differentially regulated interaction modes
Nature Cell Biology
2015
63
40
Spots and stripes: Pleomorphic patterning of stem cells via p-ERK-dependent cell chemotaxis shown by feather morphogenesis and mathematical simulation
Developmental Biology
2009
61
41
On validation and invalidation of biological models
BMC Bioinformatics
2009
60
42
Autocatalysed oxidative modifications to 2‐oxoglutarate dependent oxygenases
FEBS Journal
2012
55
43
On the Histone Lysine Methyltransferase Activity of Fungal Metabolite Chaetocin
Journal of Medicinal Chemistry
2013
54
44
Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates
Organic and Biomolecular Chemistry
2011
52
45
Engineering and ethical perspectives in synthetic biology
EMBO Reports
2012
49
46
Exploring Peptide-Membrane Interactions with Coarse-Grained MD Simulations
Biophysical Journal
2011
46
47
A Photoreactive Small-Molecule Probe for 2-Oxoglutarate Oxygenases
Chemistry and Biology
2011
46
48
Differential Localization of the Two T. brucei Poly(A) Binding Proteins to the Nucleus and RNP Granules Suggests Binding to Distinct mRNA Pools
PLoS ONE
2013
45
49
Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex
FEBS Journal
2010
44
50
CULLIN 4-RING FINGER-LIGASE plays a key role in the control of endoreplication cycles in Arabidopsis trichomes
Proceedings of the National Academy of Sciences of the United States of America
2010
44
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