| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 4 | The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms | Leukemia | 2022 | 1,211 |
| 5 | The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms | Leukemia | 2022 | 1,023 |
| 6 | COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study | Lancet, The | 2020 | 908 |
| 7 | Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial | Lancet, The | 2014 | 689 |
| 8 | Advances in Hypoxia-Inducible Factor Biology | Cell Metabolism | 2018 | 571 |
| 9 | Guidelines for the management of oesophageal and gastric cancer | Gut | 2011 | 570 |
| 10 | Biological Consequences of Radiation-induced DNA Damage: Relevance to Radiotherapy | Clinical Oncology | 2013 | 487 |
| 11 | Outcomes of patients with hematologic malignancies and COVID-19: a systematic review and meta-analysis of 3377 patients | Blood | 2020 | 479 |
| 12 | MIND: Modality independent neighbourhood descriptor for multi-modal deformable registration | Medical Image Analysis | 2012 | 478 |
| 13 | COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study | Lancet Oncology, The | 2020 | 473 |
| 14 | Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles | Nature Genetics | 2012 | 445 |
| 15 | Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge | EClinicalMedicine | 2021 | 435 |
| 16 | Consensus guidelines for the use and interpretation of angiogenesis assays | Angiogenesis | 2018 | 429 |
| 17 | The fine-scale genetic structure of the British population | Nature | 2015 | 416 |
| 18 | SETD2-Dependent Histone H3K36 Trimethylation Is Required for Homologous Recombination Repair and Genome Stability | Cell Reports | 2014 | 370 |
| 19 | Deep learning for prediction of colorectal cancer outcome: a discovery and validation study | Lancet, The | 2020 | 364 |
| 20 | In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity | Nature Biotechnology | 2015 | 362 |
| 21 | Standard electrode potentials involving radicals in aqueous solution: inorganic radicals (IUPAC Technical Report) | Pure and Applied Chemistry | 2015 | 351 |
| 22 | Activity-Based Chemical Proteomics Accelerates Inhibitor Development for Deubiquitylating Enzymes | Chemistry and Biology | 2011 | 348 |
| 23 | Diagnosis and treatment of basal cell carcinoma: European consensus–based interdisciplinary guidelines | European Journal of Cancer | 2019 | 345 |
| 24 | Multiorgan impairment in low-risk individuals with post-COVID-19 syndrome: a prospective, community-based study | BMJ Open | 2021 | 341 |
| 25 | Mammalian Base Excision Repair: the Forgotten Archangel | Nucleic Acids Research | 2013 | 306 |
| 26 | Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool's Gold? | Frontiers in Oncology | 2019 | 302 |
| 27 | Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice | Blood | 2012 | 298 |
| 28 | COVID-19 patients and the radiology department – advice from the European Society of Radiology (ESR) and the European Society of Thoracic Imaging (ESTI) | European Radiology | 2020 | 298 |
| 29 | First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials | Lancet Oncology, The | 2017 | 293 |
| 30 | Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns | Blood | 2012 | 292 |
| 31 | The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription | Molecular Cell | 2015 | 283 |
| 32 | HDAC inhibitor‐based therapies: Can we interpret the code? | Molecular Oncology | 2012 | 271 |
| 33 | Gefitinib for oesophageal cancer progressing after chemotherapy (COG): a phase 3, multicentre, double-blind, placebo-controlled randomised trial | Lancet Oncology, The | 2014 | 270 |
| 34 | Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival | Oncogene | 2015 | 245 |
| 35 | The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis | British Journal of Cancer | 2011 | 244 |
| 36 | Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation | Cancer Cell | 2015 | 244 |
| 37 | RAD51 paralogs: Roles in DNA damage signalling, recombinational repair and tumorigenesis | Seminars in Cell and Developmental Biology | 2011 | 241 |
| 38 | MUS81 promotes common fragile site expression | Nature Cell Biology | 2013 | 234 |
| 39 | Increased global transcription activity as a mechanism of replication stress in cancer | Nature Communications | 2016 | 232 |
| 40 | Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress | Oncogene | 2013 | 213 |
| 41 | Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma | Nature Medicine | 2020 | 211 |
| 42 | Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk | Nature Genetics | 2012 | 210 |
| 43 | Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens | Nature Biotechnology | 2020 | 210 |
| 44 | MRF-Based Deformable Registration and Ventilation Estimation of Lung CT | IEEE Transactions on Medical Imaging | 2013 | 208 |
| 45 | The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication | Nature Reviews Molecular Cell Biology | 2020 | 199 |
| 46 | Genetic Alterations in the Molecular Subtypes of Bladder Cancer: Illustration in the Cancer Genome Atlas Dataset | European Urology | 2017 | 195 |
| 47 | Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy | Cancer Research | 2015 | 193 |
| 48 | Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair | Molecular Cell | 2016 | 193 |
| 49 | Liver metastases | Nature Reviews Disease Primers | 2021 | 190 |
| 50 | Innate Immunity to Adenovirus | Human Gene Therapy | 2014 | 185 |
