| # | Title | Journal | Year | Citations |
|---|
| 1 | Dissolution testing as a prognostic tool for oral drug absorption: immediate release dosage forms | Pharmaceutical Research | 1998 | 893 |
| 2 | Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs | Pharmaceutical Research | 1998 | 796 |
| 3 | GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins | Chemistry and Biology | 2003 | 720 |
| 4 | Structural Basis for the Synthesis of Indirubins as Potent and Selective Inhibitors of Glycogen Synthase Kinase-3 and Cyclin-Dependent Kinases | Journal of Medicinal Chemistry | 2004 | 343 |
| 5 | A Comparative Study of Hollow Copper Sulfide Nanoparticles and Hollow Gold Nanospheres on Degradability and Toxicity | ACS Nano | 2013 | 259 |
| 6 | The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group | European Journal of Pharmaceutical Sciences | 2019 | 224 |
| 7 | Walnut extract (Juglans regia L.) and its component ellagic acid exhibit anti-inflammatory activity in human aorta endothelial cells and osteoblastic activity in the cell line KS483 | British Journal of Nutrition | 2008 | 173 |
| 8 | Synthesis and antiviral activity evaluation of some new 6-substituted 3-(1-adamantyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles | Il Farmaco | 2002 | 166 |
| 9 | Screening of some Greek aromatic plants for antioxidant activity | Phytotherapy Research | 2003 | 155 |
| 10 | Ulvan, a bioactive marine sulphated polysaccharide as a key constituent of hybrid biomaterials: A review | Carbohydrate Polymers | 2019 | 146 |
| 11 | Impact of regional differences along the gastrointestinal tract of healthy adults on oral drug absorption: An UNGAP review | European Journal of Pharmaceutical Sciences | 2019 | 146 |
| 12 | Synthesis and Antiviral Activity Evaluation of Some New Aminoadamantane Derivatives. 2 | Journal of Medicinal Chemistry | 1996 | 144 |
| 13 | Forecasting the in vivo performance of four low solubility drugs from their in vitro dissolution data | Pharmaceutical Research | 1999 | 143 |
| 14 | In Vitro and In Vivo Activities of Chios Mastic Gum Extracts and Constituents against Helicobacter pylori | Antimicrobial Agents and Chemotherapy | 2007 | 141 |
| 15 | Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review | European Journal of Pharmaceutical Sciences | 2021 | 137 |
| 16 | Terpenes with antimicrobial activity from Cretan propolis | Phytochemistry | 2009 | 135 |
| 17 | Spiro[pyrrolidine-2,2′-adamantanes]: synthesis, anti-influenza virus activity and conformational properties | Bioorganic and Medicinal Chemistry Letters | 2003 | 129 |
| 18 | Phenolic Acid Composition, Antiatherogenic and Anticancer Potential of Honeys Derived from Various Regions in Greece | PLoS ONE | 2014 | 125 |
| 19 | Prediction of Distribution Coefficient from Structure. 1. Estimation Method | Journal of Pharmaceutical Sciences | 1997 | 121 |
| 20 | Synthesis and Antiviral Activity Evaluation of Some Aminoadamantane Derivatives | Journal of Medicinal Chemistry | 1994 | 119 |
| 21 | Antifungal activities of selected aromatic plants growing wild in Greece | Molecular Nutrition and Food Research | 2002 | 115 |
| 22 | Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay | ACS Central Science | 2021 | 115 |
| 23 | Volatile halogenated metabolites from marine red algae | Phytochemistry Reviews | 2004 | 111 |
| 24 | Heterocyclic rimantadine analogues with antiviral activity | Bioorganic and Medicinal Chemistry | 2006 | 109 |
| 25 | Unusual solubility behaviour of cyclosporin A in aqueous media | Journal of Pharmacy and Pharmacology | 2011 | 108 |
| 26 | GC-MS Profiling of Diterpene Compounds in Mediterranean Propolis from Greece | Journal of Agricultural and Food Chemistry | 2010 | 107 |
| 27 | Synthesis, lipophilicity and biological evaluation of indole-containing derivatives of 1,3,4-thiadiazole and 1,2,4-triazole | Il Farmaco | 1998 | 106 |
| 28 | Natural and Synthetic 2,2-Dimethylpyranocoumarins with Antibacterial Activity | Journal of Natural Products | 2005 | 106 |
| 29 | Ursolic Acid Triggers Apoptosis and Bcl-2 Downregulation in MCF-7 Breast Cancer Cells | Cancer Investigation | 2009 | 106 |
| 30 | Chemical Composition And In-Vitro Antimicrobial Activity Of The Essential Oils Of Three Greek Achillea Species | Zeitschrift Fur Naturforschung - Section C Journal of Biosciences | 2002 | 105 |
| 31 | Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis | Circulation | 2019 | 103 |
| 32 | Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease | European Journal of Cardiovascular Prevention and Rehabilitation | 2005 | 102 |
| 33 | Synthesis antimicrobial and antifungal activity of some new 3-substituted derivatives of 4-(2,4-dichlorophenyl)-5-adamantyl-1H-1,2,4-triazole | Il Farmaco | 2002 | 101 |
| 34 | Preventive doping control analysis: liquid and gas chromatography time‐of‐flight mass spectrometry for detection of designer steroids | Rapid Communications in Mass Spectrometry | 2007 | 99 |
| 35 | 7-Bromoindirubin-3′-oxime induces caspase-independent cell death | Oncogene | 2006 | 96 |
| 36 | Recent advances and new strategies in the NMR-based identification of natural products | Current Opinion in Biotechnology | 2014 | 95 |
| 37 | The Biopharmaceutics Classification System (BCS) and the Biopharmaceutics Drug Disposition Classification System (BDDCS): Beyond guidelines | International Journal of Pharmaceutics | 2019 | 95 |
| 38 | Megistoquinones I and II, Two Quinoline Alkaloids with Antibacterial Activity from the Bark of Sarcomelicope megistophylla. | Chemical and Pharmaceutical Bulletin | 2002 | 94 |
| 39 | Ursolic acid, a naturally occurring triterpenoid, demonstrates anticancer activity on human prostate cancer cells | Journal of Cancer Research and Clinical Oncology | 2007 | 91 |
| 40 | In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration | European Journal of Pharmaceutics and Biopharmaceutics | 2019 | 91 |
| 41 | Evaluation of the Antimicrobial and Antioxidant Activities of Origanum dictamnus Extracts before and after Encapsulation in Liposomes | Molecules | 2007 | 90 |
| 42 | Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins | Oncogene | 2004 | 86 |
| 43 | Achievements in robotic automation of solvent extraction and related approaches for bioanalysis of pharmaceuticals | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2018 | 85 |
| 44 | New cytotoxic sesquiterpenes from the red algae Laurencia obtusa and Laurencia microcladia | Tetrahedron | 2006 | 84 |
| 45 | Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network | Advanced Drug Delivery Reviews | 2021 | 84 |
| 46 | Kinetics, in silico docking, molecular dynamics, and MM‐GBSA binding studies on prototype indirubins, KT5720, and staurosporine as phosphorylase kinase ATP‐binding site inhibitors: The role of water molecules examined | Proteins: Structure, Function and Bioinformatics | 2011 | 82 |
| 47 | Chemical Analysis and Antimicrobial Activity of Greek Propolis | Planta Medica | 2004 | 81 |
| 48 | Reevaluation of bioactivity and antioxidant activity of Myrtus communis extract before and after encapsulation in liposomes | European Food Research and Technology | 2008 | 79 |
| 49 | Preventive doping control screening analysis of prohibited substances in human urine using rapid‐resolution liquid chromatography/high‐resolution time‐of‐flight mass spectrometry | Rapid Communications in Mass Spectrometry | 2010 | 78 |
| 50 | Gastric juice as a dissolution medium: Surface tension and pH | European Journal of Drug Metabolism and Pharmacokinetics | 1998 | 76 |
