| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations | American Journal of Respiratory and Critical Care Medicine | 2016 | 2,385 |
| 3 | Machine learning applications in cancer prognosis and prediction | Computational and Structural Biotechnology Journal | 2015 | 2,059 |
| 4 | Functional impact of global rare copy number variation in autism spectrum disorders | Nature | 2010 | 1,803 |
| 5 | Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure | Cell Host and Microbe | 2020 | 1,746 |
| 6 | Cellular Senescence: Defining a Path Forward | Cell | 2019 | 1,551 |
| 7 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 8 | Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity | Science | 2014 | 1,338 |
| 9 | 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus | Annals of the Rheumatic Diseases | 2019 | 1,265 |
| 10 | Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial | Lancet, The | 2015 | 1,175 |
| 11 | Periodontitis and diabetes: a two-way relationship | Diabetologia | 2012 | 1,085 |
| 12 | Effects of long-term exposure to air pollution on natural-cause mortality: an analysis of 22 European cohorts within the multicentre ESCAPE project | Lancet, The | 2014 | 1,077 |
| 13 | Osteonecrosis of the Jaw in Cancer After Treatment With Bisphosphonates: Incidence and Risk Factors | Journal of Clinical Oncology | 2005 | 990 |
| 14 | Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline | Clinical Microbiology and Infection | 2018 | 942 |
| 15 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 16 | Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes | Cell Host and Microbe | 2012 | 926 |
| 17 | Obesity and cancer risk: Emerging biological mechanisms and perspectives | Metabolism: Clinical and Experimental | 2019 | 821 |
| 18 | 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus | Annals of the Rheumatic Diseases | 2019 | 759 |
| 19 | Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases | European Heart Journal | 2016 | 757 |
| 20 | Nonalcoholic Fatty Liver Disease: Pathology and Pathogenesis | Annual Review of Pathology: Mechanisms of Disease | 2010 | 710 |
| 21 | Data-based analysis, modelling and forecasting of the COVID-19 outbreak | PLoS ONE | 2020 | 657 |
| 22 | Chronic pulmonary aspergillosis: rationale and clinical guidelines for diagnosis and management | European Respiratory Journal | 2016 | 654 |
| 23 | Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa | Nature Genetics | 2019 | 641 |
| 24 | Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology | Nature Genetics | 2021 | 629 |
| 25 | Harmonization of Pulsed-Field Gel Electrophoresis Protocols for Epidemiological Typing of Strains of Methicillin-Resistant Staphylococcus aureus : a Single Approach Developed by Consensus in 10 European Laboratories and Its Application for Tracing the Spread of Related Strains | Journal of Clinical Microbiology | 2003 | 611 |
| 26 | EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome | Annals of the Rheumatic Diseases | 2017 | 590 |
| 27 | Glioblastoma multiforme: Pathogenesis and treatment | Annals of the Rheumatic Diseases | 2015 | 588 |
| 28 | The value of antimicrobial peptides in the age of resistance | Lancet Infectious Diseases, The | 2020 | 573 |
| 29 | Lifestyle and impact on cardiovascular risk factor control in coronary patients across 27 countries: Results from the European Society of Cardiology ESC-EORP EUROASPIRE V registry | European Journal of Preventive Cardiology | 2019 | 558 |
| 30 | International Consensus Guidelines for the Optimal Use of the Polymyxins: Endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti‐infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP) | Pharmacotherapy | 2019 | 545 |
| 31 | Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event | Infection, Genetics and Evolution | 2020 | 544 |
| 32 | A genome-wide scan for common alleles affecting risk for autism | Human Molecular Genetics | 2010 | 538 |
| 33 | ROS/oxidative stress signaling in osteoarthritis | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2016 | 521 |
| 34 | Effects of Cold Weather on Mortality: Results From 15 European Cities Within the PHEWE Project | American Journal of Epidemiology | 2008 | 509 |
| 35 | The TREAT-NMD DMD Global Database: Analysis of More than 7,000 Duchenne Muscular Dystrophy Mutations | Human Mutation | 2015 | 507 |
| 36 | A guiding map for inflammation | Nature Immunology | 2017 | 506 |
| 37 | Maternal and Fetal Hypothalamic-Pituitary-Adrenal Axes During Pregnancy and Postpartum | Annals of the New York Academy of Sciences | 2003 | 500 |
| 38 | The Malassezia Genus in Skin and Systemic Diseases | Clinical Microbiology Reviews | 2012 | 494 |
| 39 | Consensus on the use and interpretation of cystic fibrosis mutation analysis in clinical practice | Journal of Cystic Fibrosis | 2008 | 493 |
| 40 | Venetoclax plus LDAC for newly diagnosed AML ineligible for intensive chemotherapy: a phase 3 randomized placebo-controlled trial | Blood | 2020 | 470 |
| 41 | Cirse Quality Assurance Document and Standards for Classification of Complications: The Cirse Classification System | CardioVascular and Interventional Radiology | 2017 | 467 |
| 42 | 2019 Update of the Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA–EDTA) recommendations for the management of lupus nephritis | Annals of the Rheumatic Diseases | 2020 | 463 |
| 43 | Global evolution of multidrug-resistant Acinetobacter baumannii clonal lineages | International Journal of Antimicrobial Agents | 2013 | 452 |
| 44 | Population Pharmacokinetic Analysis of Colistin Methanesulfonate and Colistin after Intravenous Administration in Critically Ill Patients with Infections Caused by Gram-Negative Bacteria | Antimicrobial Agents and Chemotherapy | 2009 | 448 |
| 45 | Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis | Nature Immunology | 2016 | 437 |
| 46 | Medical and Surgical Education Challenges and Innovations in the COVID-19 Era: A Systematic Review | In Vivo | 2020 | 437 |
| 47 | A European Respiratory Society technical standard: exhaled biomarkers in lung disease | European Respiratory Journal | 2017 | 432 |
| 48 | Endoscopic biliary stenting: indications, choice of stents, and results: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline – Updated October 2017 | Endoscopy | 2018 | 425 |
| 49 | Obesity and cardiovascular disease: revisiting an old relationship | Metabolism: Clinical and Experimental | 2019 | 416 |
| 50 | Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targets | Nature Reviews Drug Discovery | 2007 | 400 |
