| # | Title | Journal | Year | Citations |
|---|
| 1 | Fusion protein linkers: Property, design and functionality | Advanced Drug Delivery Reviews | 2013 | 1,273 |
| 2 | MONOAMINE OXIDASE: From Genes to Behavior | Annual Review of Neuroscience | 1999 | 1,070 |
| 3 | Progesterone receptors: Form and function in brain | Frontiers in Neuroendocrinology | 2008 | 531 |
| 4 | Differences In Life Expectancy Due To Race And Educational Differences Are Widening, And Many May Not Catch Up | Health Affairs | 2012 | 522 |
| 5 | Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases | Theranostics | 2017 | 502 |
| 6 | Monoamine oxidase inactivation: From pathophysiology to therapeutics | Advanced Drug Delivery Reviews | 2008 | 490 |
| 7 | Antioxidant and Prooxidant Activities of α-Lipoic Acid and Dihydrolipoic Acid | Toxicology and Applied Pharmacology | 2002 | 465 |
| 8 | Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space | Biochemical Journal | 2001 | 464 |
| 9 | Molecular aspects of lipoic acid in the prevention of diabetes complications | Nutrition | 2001 | 460 |
| 10 | Biopharmaceutics classification system: the scientific basis for biowaiver extensions | Pharmaceutical Research | 2002 | 460 |
| 11 | Age, APOE and sex: Triad of risk of Alzheimer’s disease | Journal of Steroid Biochemistry and Molecular Biology | 2016 | 443 |
| 12 | Estimation of H2 O2 gradients across biomembranes | FEBS Letters | 2000 | 438 |
| 13 | Quantitative structure-activity relationship analysis of phenolic antioxidants | Free Radical Biology and Medicine | 1999 | 430 |
| 14 | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1 | Journal of Lipid Research | 2000 | 423 |
| 15 | Topical Ocular Drug Delivery: Recent Developments and Future Challenges | Journal of Ocular Pharmacology and Therapeutics | 1986 | 416 |
| 16 | The mouse cortico-striatal projectome | Nature Neuroscience | 2016 | 412 |
| 17 | Cell Penetrating Peptides: Intracellular Pathways and Pharmaceutical Perspectives | Pharmaceutical Research | 2007 | 398 |
| 18 | Mitochondrial free radical production and cell signaling | Molecular Aspects of Medicine | 2004 | 388 |
| 19 | Targeting receptor-mediated endocytotic pathways with nanoparticles: Rationale and advances | Advanced Drug Delivery Reviews | 2013 | 373 |
| 20 | Leydig cells: formation, function, and regulation† | Biology of Reproduction | 2018 | 370 |
| 21 | PTEN: Tumor Suppressor and Metabolic Regulator | Frontiers in Endocrinology | 2018 | 365 |
| 22 | BCL2 translocation frequency rises with age in humans. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 355 |
| 23 | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3 | Journal of Lipid Research | 2000 | 353 |
| 24 | Estrogen: A master regulator of bioenergetic systems in the brain and body | Frontiers in Neuroendocrinology | 2014 | 350 |
| 25 | Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action | Journal of Pharmacology and Experimental Therapeutics | 1988 | 344 |
| 26 | From The Cover: Structure of membrane-bound -synuclein studied by site-directed spin labeling | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 343 |
| 27 | Penetration and enzymatic barriers to peptide and protein absorption | Advanced Drug Delivery Reviews | 1989 | 340 |
| 28 | Compliance with drug therapies for the treatment and prevention of osteoporosis | Maturitas | 2004 | 340 |
| 29 | Patient‐reported reasons for discontinuing overactive bladder medication | BJU International | 2010 | 336 |
| 30 | Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space | Biochemical Journal | 2001 | 330 |
| 31 | Effectiveness of a lifestyle intervention in promoting the well-being of independently living older people: results of the Well Elderly 2 Randomised Controlled Trial | Journal of Epidemiology and Community Health | 2012 | 327 |
| 32 | The national cost of hospital‐acquired pressure injuries in the United States | International Wound Journal | 2019 | 320 |
| 33 | Structural Organization of α-Synuclein Fibrils Studied by Site-directed Spin Labeling | Journal of Biological Chemistry | 2003 | 316 |
| 34 | miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma | Cell Death and Differentiation | 2018 | 308 |
| 35 | Impact of Visual Field Loss on Health-Related Quality of Life in Glaucoma | Ophthalmology | 2008 | 303 |
| 36 | MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide | Neurobiology of Aging | 2002 | 301 |
| 37 | Anticonvulsant profile of the progesterone metabolite 5α-pregnan-3α-ol-20-one | European Journal of Pharmacology | 1989 | 297 |
| 38 | A Gene Cluster Containing Two Fungal Polyketide Synthases Encodes the Biosynthetic Pathway for a Polyketide, Asperfuranone, in Aspergillus nidulans | Journal of the American Chemical Society | 2009 | 292 |
| 39 | Anxiolytic activity of the progesterone metabolite 5α-pregnan-3α-ol-20-one | Brain Research | 1991 | 287 |
| 40 | Perimenopause as a neurological transition state | Nature Reviews Endocrinology | 2015 | 286 |
| 41 | Oxygen free radicals and Parkinson's disease | Free Radical Biology and Medicine | 1991 | 278 |
| 42 | Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment | Nature Communications | 2020 | 256 |
| 43 | Synthesis, Biological Evaluation, and Quantitative Structure−Activity Relationship Analysis of New Schiff Bases of Hydroxysemicarbazide as Potential Antitumor Agents | Journal of Medicinal Chemistry | 2002 | 254 |
| 44 | Antioxidant and prooxidant functions of DT-diaphorase in quinone metabolism | Biochemical Pharmacology | 1995 | 253 |
| 45 | Increased stress response and β–phenylethylamine in MAOB–deficient mice | Nature Genetics | 1997 | 251 |
| 46 | Medication Adherence and Associated Hemoglobin A1c in Type 2 Diabetes | Annals of Pharmacotherapy | 2004 | 248 |
| 47 | Apoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal rupture | Biochemical Journal | 2001 | 246 |
| 48 | Human monoamine oxidase A and B genes exhibit identical exon-intron organization. | Proceedings of the National Academy of Sciences of the United States of America | 1991 | 244 |
| 49 | The influence of phospholipase A2 and glutathione peroxidase on the elimination of membrane lipid peroxides | Archives of Biochemistry and Biophysics | 1983 | 243 |
| 50 | NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity | Cancer Research | 1992 | 234 |
