| # | Title | Journal | Year | Citations |
|---|
| 1 | Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China | JAMA Cardiology | 2020 | 3,373 |
| 2 | Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019 | European Heart Journal | 2020 | 380 |
| 3 | Exosomes from nicotine-stimulated macrophages accelerate atherosclerosis through miR-21-3p/PTEN-mediated VSMC migration and proliferation | Theranostics | 2019 | 245 |
| 4 | MicroRNA-1 Regulates Cardiomyocyte Apoptosis by Targeting Bcl-2 | International Heart Journal | 2009 | 236 |
| 5 | High salt primes a specific activation state of macrophages, M(Na) | Cell Research | 2015 | 189 |
| 6 | Angiographic quantitative flow ratio-guided coronary intervention (FAVOR III China): a multicentre, randomised, sham-controlled trial | Lancet, The | 2021 | 175 |
| 7 | Insights Into Echo-Attenuated Plaques, Echolucent Plaques, and Plaques With Spotty Calcification | Journal of the American College of Cardiology | 2014 | 170 |
| 8 | Cardiomyocyte-expressed farnesoid-X-receptor is a novel apoptosis mediator and contributes to myocardial ischaemia/reperfusion injury | European Heart Journal | 2013 | 163 |
| 9 | Cardiac resynchronization therapy by left bundle branch area pacing in patients with heart failure and left bundle branch block | Heart Rhythm | 2019 | 146 |
| 10 | The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling | Nature Communications | 2016 | 143 |
| 11 | Vitamin D Receptor Activation Protects Against Myocardial Reperfusion Injury Through Inhibition of Apoptosis and Modulation of Autophagy | Antioxidants and Redox Signaling | 2015 | 140 |
| 12 | The nuclear melatonin receptor RORα is a novel endogenous defender against myocardial ischemia/reperfusion injury | Journal of Pineal Research | 2016 | 126 |
| 13 | Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design | Nature Communications | 2021 | 124 |
| 14 | STABLE-SR (Electrophysiological Substrate Ablation in the Left Atrium During Sinus Rhythm) for the Treatment of Nonparoxysmal Atrial Fibrillation | Circulation: Arrhythmia and Electrophysiology | 2017 | 119 |
| 15 | The biological effects of individual-level PM2.5exposure on systemic immunity and inflammatory response in traffic policemen | Occupational and Environmental Medicine | 2013 | 113 |
| 16 | Circular RNA Ttc3 regulates cardiac function after myocardial infarction by sponging miR-15b | Journal of Molecular and Cellular Cardiology | 2019 | 99 |
| 17 | A hierarchical method based on weighted extreme gradient boosting in ECG heartbeat classification | Computer Methods and Programs in Biomedicine | 2019 | 98 |
| 18 | Clinical Adverse Effects of Endothelin Receptor Antagonists: Insights From the Meta‐Analysis of 4894 Patients From 24 Randomized Double‐Blind Placebo‐Controlled Clinical Trials | Journal of the American Heart Association | 2016 | 92 |
| 19 | MicroRNA-9 Inhibits NLRP3 Inflammasome Activation in Human Atherosclerosis Inflammation Cell Models through the JAK1/STAT Signaling Pathway | Cellular Physiology and Biochemistry | 2017 | 92 |
| 20 | GATA5 loss-of-function mutations associated with congenital bicuspid aortic valve | International Journal of Molecular Medicine | 2014 | 88 |
| 21 | Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NFκB Pathway Suppression | Journal of Diabetes Research | 2016 | 88 |
| 22 | Discovery of cryptic allosteric sites using reversed allosteric communication by a combined computational and experimental strategy | Chemical Science | 2021 | 84 |
| 23 | MicroRNA-223 protects neonatal rat cardiomyocytes and H9c2 cells from hypoxia-induced apoptosis and excessive autophagy via the Akt/mTOR pathway by targeting PARP-1 | Journal of Molecular and Cellular Cardiology | 2018 | 82 |
| 24 | Atorvastatin Inhibits Inflammatory Response, Attenuates Lipid Deposition, and Improves the Stability of Vulnerable Atherosclerotic Plaques by Modulating Autophagy | Frontiers in Pharmacology | 2018 | 75 |
| 25 | A Novel NKX2.5 Loss-of-Function Mutation Associated With Congenital Bicuspid Aortic Valve | American Journal of Cardiology | 2014 | 74 |
| 26 | Air pollution is associated with the development of atherosclerosis via the cooperation of CD36 and NLRP3 inflammasome in ApoE -/- mice | Toxicology Letters | 2018 | 74 |
| 27 | Inhibition of BRD4 attenuates transverse aortic constriction- and TGF-β-induced endothelial-mesenchymal transition and cardiac fibrosis | Journal of Molecular and Cellular Cardiology | 2019 | 74 |
| 28 | A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting | Cell Stem Cell | 2021 | 74 |
| 29 | Efficacy and Safety of a Pharmaco-Invasive Strategy With Half-Dose Alteplase Versus Primary Angioplasty in ST-Segment–Elevation Myocardial Infarction | Circulation | 2017 | 73 |
| 30 | Nicotine-mediated autophagy of vascular smooth muscle cell accelerates atherosclerosis via nAChRs/ROS/NF-κB signaling pathway | Atherosclerosis | 2019 | 73 |
| 31 | Recombinant human interleukin-1 receptor antagonist protects mice against acute doxorubicin-induced cardiotoxicity | European Journal of Pharmacology | 2010 | 71 |
| 32 | Prognostic value of serum galectin-3 in patients with heart failure: A meta-analysis | International Journal of Cardiology | 2015 | 70 |
| 33 | Effects of Intensive Antihypertensive Treatment on Chinese Hypertensive Patients Older Than 70 Years | Journal of Clinical Hypertension | 2013 | 69 |
| 34 | Effect of Vitamin E and Omega-3 Fatty Acids on Protecting Ambient PM2.5-Induced Inflammatory Response and Oxidative Stress in Vascular Endothelial Cells | PLoS ONE | 2016 | 69 |
| 35 | RNA m6A Modification in Cancers: Molecular Mechanisms and Potential Clinical Applications | Innovation(China) | 2020 | 69 |
| 36 | Roles of Cells from the Arterial Vessel Wall in Atherosclerosis | Mediators of Inflammation | 2017 | 68 |
| 37 | A high-precision arrhythmia classification method based on dual fully connected neural network | Biomedical Signal Processing and Control | 2020 | 68 |
| 38 | DNA Walkers for Biosensing Development | Advanced Science | 2022 | 68 |
| 39 | Emergence of allosteric drug-resistance mutations: new challenges for allosteric drug discovery | Drug Discovery Today | 2020 | 67 |
| 40 | Targeting HDAC6 attenuates nicotine-induced macrophage pyroptosis via NF-κB/NLRP3 pathway | Atherosclerosis | 2021 | 65 |
| 41 | circHIPK3 regulates lung fibroblast-to-myofibroblast transition by functioning as a competing endogenous RNA | Cell Death and Disease | 2019 | 64 |
| 42 | Automated heartbeat classification based on deep neural network with multiple input layers | Knowledge-Based Systems | 2020 | 63 |
| 43 | Suppressor of IKKɛ is an essential negative regulator of pathological cardiac hypertrophy | Nature Communications | 2016 | 60 |
| 44 | Epidemiologic Features of Kawasaki Disease in Shanghai From 2013 Through 2017 | Journal of Epidemiology | 2020 | 60 |
| 45 | Propofol and arrhythmias: two sides of the coin | Acta Pharmacologica Sinica | 2011 | 58 |
| 46 | Fabrication of a Novel Polymer-Free Nanostructured Drug-Eluting Coating for Cardiovascular Stents | ACS Applied Materials & Interfaces | 2013 | 58 |
| 47 | Cigarette Smoking and Adipose Tissue: The Emerging Role in Progression of Atherosclerosis | Mediators of Inflammation | 2017 | 58 |
| 48 | Beneficial effects of catheter ablation of frequent premature ventricular complexes on left ventricular function | Heart | 2014 | 57 |
| 49 | TBX20 loss-of-function mutation responsible for familial tetralogy of Fallot or sporadic persistent truncus arteriosus | International Journal of Medical Sciences | 2017 | 57 |
| 50 | Epicardial adipose tissue and atrial fibrillation: Possible mechanisms, potential therapies, and future directions | PACE - Pacing and Clinical Electrophysiology | 2020 | 57 |
