| # | Title | Journal | Year | Citations |
|---|
| 1 | Loss of non-coding RNA expression from the DLK1-DIO3 imprinted locus correlates with reduced neural differentiation potential in human embryonic stem cell lines | Stem Cell Research and Therapy | 2015 | 198 |
| 2 | The Molecular Basis of Viral Inhibition of IRF- and STAT-Dependent Immune Responses | Frontiers in Immunology | 2018 | 90 |
| 3 | Coregulation of transcription factors and microRNAs in human transcriptional regulatory network | BMC Bioinformatics | 2011 | 84 |
| 4 | Integrative transcriptome sequencing reveals extensive alternative trans-splicing and cis-backsplicing in human cells | Nucleic Acids Research | 2018 | 62 |
| 5 | Oversampling to Overcome Overfitting: Exploring the Relationship between Data Set Composition, Molecular Descriptors, and Predictive Modeling Methods | Journal of Chemical Information and Modeling | 2013 | 53 |
| 6 | Discovery of Genes Related to Insecticide Resistance in Bactrocera dorsalis by Functional Genomic Analysis of a De Novo Assembled Transcriptome | PLoS ONE | 2012 | 46 |
| 7 | Lengthening of 3′UTR increases with morphological complexity in animal evolution | Bioinformatics | 2012 | 45 |
| 8 | Neutrophil Extracellular Traps Impair Intestinal Barrier Function during Experimental Colitis | Biomedicines | 2020 | 45 |
| 9 | miR-338-5p inhibits cell proliferation, colony formation, migration and cisplatin resistance in esophageal squamous cancer cells by targeting FERMT2 | Carcinogenesis | 2019 | 38 |
| 10 | Clinical implications of sequential MRD monitoring by NGS at 2 time points after chemotherapy in patients with AML | Blood Advances | 2021 | 31 |
| 11 | Biochemical and Cellular Evidence Demonstrating AKT-1 as a Binding Partner for Resveratrol Targeting Protein NQO2 | PLoS ONE | 2014 | 30 |
| 12 | Dissecting the Human Protein-Protein Interaction Network via Phylogenetic Decomposition | Scientific Reports | 2014 | 30 |
| 13 | AKT/mTOR as Novel Targets of Polyphenol Piceatannol Possibly Contributing to Inhibition of Proliferation of Cultured Prostate Cancer Cells | ISRN Urology | 2012 | 29 |
| 14 | Dual Targeting of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Histone Deacetylase as a Therapy for Colorectal Cancer | EBioMedicine | 2016 | 28 |
| 15 | Functions of DNA methyltransferase 3‐like in germ cells and beyond | Biology of the Cell | 2012 | 26 |
| 16 | Efficient Generation of Chemically Induced Mesenchymal Stem Cells from Human Dermal Fibroblasts | Scientific Reports | 2017 | 26 |
| 17 | NK cell receptor and ligand composition influences the clearance of SARS-CoV-2 | Journal of Clinical Investigation | 2021 | 26 |
| 18 | Incorporation of long non-coding RNA expression profile in the 2017 ELN risk classification can improve prognostic prediction of acute myeloid leukemia patients | EBioMedicine | 2019 | 23 |
| 19 | The extracellular SEMA domain attenuates intracellular apoptotic signaling of semaphorin 6A in lung cancer cells | Oncogenesis | 2018 | 17 |
| 20 | Benchmarking differential expression, imputation and quantification methods for proteomics data | Briefings in Bioinformatics | 2022 | 16 |
| 21 | De novo motif discovery facilitates identification of interactions between transcription factors in Saccharomyces cerevisiae | Bioinformatics | 2012 | 15 |
| 22 | Emergence of differentially regulated pathways associated with the development of regional specificity in chicken skin | BMC Genomics | 2015 | 15 |
| 23 | Solution structure and base specificity of cytotoxic RC-RNase 2 from Rana catesbeiana | Archives of Biochemistry and Biophysics | 2015 | 15 |
| 24 | Kinesin-5 Contributes to Spindle-length Scaling in the Evolution of Cancer toward Metastasis | Scientific Reports | 2016 | 14 |
| 25 | Expression of HOXB genes is significantly different in acute myeloid leukemia with a partial tandem duplication of MLL vs. a MLL translocation: a cross-laboratory study | Cancer Genetics | 2011 | 12 |
| 26 | Structural basis for DNA-mediated allosteric regulation facilitated by the AAA+module of Lon protease | Acta Crystallographica Section D: Biological Crystallography | 2014 | 12 |
| 27 | Membrane Protein Modification Modulates Big and Small Extracellular Vesicle Biodistribution and Tumorigenic Potential in Breast Cancers In Vivo | Advanced Materials | 2023 | 12 |
| 28 | Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation | Experimental and Molecular Medicine | 2017 | 11 |
| 29 | Noncanonical expression of caudal during early embryogenesis in the pea aphid Acyrthosiphon pisum: maternal cad‐driven posterior development is not conserved | Insect Molecular Biology | 2013 | 10 |
| 30 | Leaf structure affects a plant’s appearance: combined multiple-mechanisms intensify remarkable foliar variegation | Journal of Plant Research | 2017 | 10 |
| 31 | DynaPho: a web platform for inferring the dynamics of time-series phosphoproteomics | Bioinformatics | 2017 | 9 |
| 32 | Stage-dependent piRNAs in chicken implicated roles in modulating male germ cell development | BMC Genomics | 2018 | 9 |
| 33 | Crystal Structures and Molecular Dynamics Simulations of Thermophilic Malate Dehydrogenase Reveal Critical Loop Motion for Co-Substrate Binding | PLoS ONE | 2013 | 8 |
| 34 | Setting boundaries for genome-wide heterochromatic DNA deletions through flanking inverted repeats in Tetrahymena thermophila | Nucleic Acids Research | 2019 | 8 |
| 35 | Evidence for complex dynamics during U2 snRNP selection of the intron branchpoint | Nucleic Acids Research | 2021 | 8 |
| 36 | HLJ1 amplifies endotoxin-induced sepsis severity by promoting IL-12 heterodimerization in macrophages | ELife | 0 | 8 |
| 37 | Cloning, overexpression, purification and crystallization of malate dehydrogenase fromThermus thermophilus | Acta Crystallographica Section F: Structural Biology Communications | 2013 | 7 |
| 38 | Discovery of genes related to formothion resistance in oriental fruit fly (Bactrocera dorsalis) by a constrained functional genomics analysis | Insect Molecular Biology | 2015 | 7 |
| 39 | Trend, characteristics, and pharmacotherapy of adults diagnosed with attention-deficit/hyperactivity disorder: a nationwide survey in Taiwan | Neuropsychiatric Disease and Treatment | 2017 | 7 |
| 40 | Phylogenetic and Structural Analysis of NIN-Like Proteins With a Type I/II PB1 Domain That Regulates Oligomerization for Nitrate Response | Frontiers in Plant Science | 2021 | 7 |
| 41 | Exploration of the Proteomic Landscape of Small Extracellular Vesicles in Serum as Biomarkers for Early Detection of Colorectal Neoplasia | Frontiers in Oncology | 2021 | 7 |
| 42 | phiC31 integrase for recombination-mediated single-copy insertion and genome manipulation in Caenorhabditis elegans | Genetics | 2022 | 7 |
| 43 | Multiple Conformations of the Loop Region Confers Heat‐Resistance on SsArd1, a Thermophilic NatA | ChemBioChem | 2016 | 6 |
| 44 | Functional Characteristics of the Flying Squirrel's Cecal Microbiota under a Leaf-Based Diet, Based on Multiple Meta-Omic Profiling | Frontiers in Microbiology | 2017 | 5 |
| 45 | Reduction of germ cells in the <i>Odysseus</i> null mutant causes male fertility defect in <i>Drosophila melanogaster</i> | Genes and Genetic Systems | 2012 | 4 |
| 46 | Microtubule-Mediated NLRP3 Inflammasome Activation Is Independent of Microtubule-Associated Innate Immune Factor GEF-H1 in Murine Macrophages | International Journal of Molecular Sciences | 2020 | 4 |
| 47 | Podocalyxin‐Like Protein 1 Regulates Pluripotency through the Cholesterol Biosynthesis Pathway | Advanced Science | 2023 | 4 |
| 48 | Identification of Critical Conditions for Immunostaining in the Pea Aphid Embryos: Increasing Tissue Permeability and Decreasing Background Staining | Journal of Visualized Experiments | 2016 | 3 |
| 49 | Germline expression of the hunchback orthologues in the asexual viviparous aphids: a conserved feature within the Aphididae | Insect Molecular Biology | 2018 | 3 |
| 50 | Evolutionary Trajectories and Genomic Divergence in Localized Breast Cancers after Ipsilateral Breast Tumor Recurrence | Cancers | 2021 | 3 |
