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Top Articles

#TitleJournalYearCitations
1Effect of the Proton Pump Inhibitor Esomeprazole on the Oral Absorption and Pharmacokinetics of NilotinibJournal of Clinical Pharmacology201076
2Nilotinib population pharmacokinetics and exposure-response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemiaEuropean Journal of Clinical Pharmacology201370
3Relationship between everolimus exposure and safety and efficacy: Meta-analysis of clinical trials in oncologyEuropean Journal of Cancer201466
4Effects of Rifampin and Ketoconazole on the Pharmacokinetics of Nilotinib in Healthy ParticipantsJournal of Clinical Pharmacology201161
5Effects of imatinib (Glivec) on the pharmacokinetics of metoprolol, a CYP2D6 substrate, in Chinese patients with chronic myelogenous leukaemiaBritish Journal of Clinical Pharmacology200850
6Phase II study of dovitinib in patients with metastatic and/or unresectable gastrointestinal stromal tumours after failure of imatinib and sunitinibBritish Journal of Cancer201349
7Dose‐ and Time‐Dependent Pharmacokinetics of Midostaurin in Patients With Diabetes MellitusJournal of Clinical Pharmacology200838
8Clinical Pharmacology of DeferasiroxClinical Pharmacokinetics201433
9A Mechanism-Based Population Pharmacokinetic Model for Characterizing Time-Dependent Pharmacokinetics of Midostaurin and its Metabolites in Human SubjectsClinical Pharmacokinetics200826
10Concurrent use of proton pump inhibitors or H2 blockers did not adversely affect nilotinib efficacy in patients with chronic myeloid leukemiaCancer Chemotherapy and Pharmacology201225
11Pharmacokinetic drug–drug interaction assessment between LCZ696, an angiotensin receptor neprilysin inhibitor, and hydrochlorothiazide, amlodipine, or carvedilolClinical Pharmacology in Drug Development201520
12Effects of imatinib mesylate on the pharmacokinetics of paracetamol (acetaminophen) in Korean patients with chronic myelogenous leukaemiaBritish Journal of Clinical Pharmacology201119
13Nilotinib for imatinib-resistant or -intolerant chronic myeloid leukemia in chronic phase, accelerated phase, or blast crisis: A single- and multiple-dose, open-label pharmacokinetic study in Chinese patientsClinical Therapeutics200918
14Effects of famotidine or an antacid preparation on the pharmacokinetics of nilotinib in healthy volunteersCancer Chemotherapy and Pharmacology201312
15Correlation between Nasal Membrane Permeability and Nasal Absorption RateAAPS PharmSciTech20136
16Population Pharmacokinetics of Subcutaneous Pasireotide in Healthy Volunteers and Cushing’s Disease PatientsClinical Pharmacokinetics20183
17CYP3A5 but Not CYP2D6 Polymorphism Contributes Significantly to the Variability in Dextropropoxyphene DispositionJournal of Clinical Pharmacology20102
18Development and validation of an LC–MS/MS method for the quantitative analysis of the adenosine A2a receptor antagonist NIR178 and its monohydroxy metabolite in human plasma: Application to clinical pharmacokineticsBiomedical Chromatography20202
19Meta-analysis on the relationship between everolimus exposure and safety and efficacy.Journal of Clinical Oncology20121
20Octreotide (Oct) Lar Reconstituted in a New Vehicle (Nv): Phase 1, Open-Label, Randomized, Bioequivalence Study Vs Oct Lar 30 Mg (Current Vehicle)Annals of Oncology20140
21Assessment of gastric pH changes and food intake on ribociclib bioavailability: In silico and clinical evaluationsAnnals of Oncology20170