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Top Articles

#TitleJournalYearCitations
1Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virusNature20052,136
2Global analysis of protein phosphorylation in yeastNature2005915
3Sch9 Is a Major Target of TORC1 in Saccharomyces cerevisiaeMolecular Cell2007723
4TRIM5 is an innate immune sensor for the retrovirus capsid latticeNature2011569
5The nuclear pore complex: bridging nuclear transport and gene regulationNature Reviews Molecular Cell Biology2010473
6New insights into myosin evolution and classificationProceedings of the National Academy of Sciences of the United States of America2006430
7Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanomaNature Genetics2012369
8Mechanisms of pathogen entry through the endosomal compartmentsNature Reviews Molecular Cell Biology2006324
9Toxoplasma Profilin Is Essential for Host Cell Invasion and TLR11-Dependent Induction of an Interleukin-12 ResponseCell Host and Microbe2008320
10A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondiiImmunity2012311
11Gliding motility powers invasion and egress in ApicomplexaNature Reviews Microbiology2017291
12TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral PathwayImmunity2008280
13Mitochondrial dynamics regulate the RIG‐I‐like receptor antiviral pathwayEMBO Reports2010257
14Functional Dissection of the Apicomplexan Glideosome Molecular ArchitectureCell Host and Microbe2010256
15HIV-1 Vpu Neutralizes the Antiviral Factor Tetherin/BST-2 by Binding It and Directing Its Beta-TrCP2-Dependent DegradationPLoS Pathogens2009248
16Infectious viral load in unvaccinated and vaccinated individuals infected with ancestral, Delta or Omicron SARS-CoV-2Nature Medicine2022239
17Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage KineticsPLoS Pathogens2009233
18A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3Journal of Experimental Medicine2009215
19Rhamnolipids Are Virulence Factors That Promote Early Infiltration of Primary Human Airway Epithelia by Pseudomonas aeruginosaInfection and Immunity2006211
20IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmissionELife2018198
21Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathwayJournal of Cell Biology2004197
22The TOR signalling network from yeast to manInternational Journal of Biochemistry and Cell Biology2006194
23Influenza A virus infection impacts systemic microbiota dynamics and causes quantitative enteric dysbiosisMicrobiome2018194
24Analysis of antibiotic resistance gene expression inPseudomonas aeruginosaby quantitative real-time-PCRFEMS Microbiology Letters2006192
25TRIM Protein-Mediated Regulation of Inflammatory and Innate Immune Signaling and Its Association with Antiretroviral ActivityJournal of Virology2013189
26HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotencyRetrovirology2012188
27Caffeine extends yeast lifespan by targeting TORC1Molecular Microbiology2008186
28Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosisJournal of Cell Biology2006184
29Intra-endosomal membrane trafficTrends in Cell Biology2006177
30Contribution of Toll-like receptors to the innate immune response to Gram-negative and Gram-positive bacteriaBlood2007171
31Paramyxovirus mRNA editing, the ‘rule of six’ and error catastrophe: a hypothesisJournal of General Virology2005168
32A Copper-Activated Two-Component System Interacts with Zinc and Imipenem Resistance in Pseudomonas aeruginosaJournal of Bacteriology2007163
33A high-stringency blueprint of the human proteomeNature Communications2020152
34Phosphatidic Acid-Mediated Signaling Regulates Microneme Secretion in ToxoplasmaCell Host and Microbe2016147
35Quorum Sensing Inhibition Selects for Virulence and Cooperation in Pseudomonas aeruginosaPLoS Pathogens2010146
36Validation of a commercially available SARS-CoV-2 serological immunoassayClinical Microbiology and Infection2020146
37Bacterial invasion via lipid raftsCellular Microbiology2005143
38Anthrax toxin: the long and winding road that leads to the killTrends in Microbiology2005138
39Plasticity and redundancy among AMA–RON pairs ensure host cell entry of Toxoplasma parasitesNature Communications2014138
40Regulation of G0 entry by the Pho80–Pho85 cyclin–CDK complexEMBO Journal2005135
41ATF6β is a host cellular target of the Toxoplasma gondii virulence factor ROP18Journal of Experimental Medicine2011133
42Modified cyclodextrins as broad-spectrum antiviralsScience Advances2020131
43A type III-like restriction endonuclease functions as a major barrier to horizontal gene transfer in clinical Staphylococcus aureus strainsProceedings of the National Academy of Sciences of the United States of America2010130
44TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasmRetrovirology2013129
45Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysisProceedings of the National Academy of Sciences of the United States of America2009121
46A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egressScience2017121
47Late Endosomal Cholesterol Accumulation Leads to Impaired Intra-Endosomal TraffickingPLoS ONE2007119
48Microneme protein 8 – a new essential invasion factor inToxoplasma gondiiJournal of Cell Science2008117
49Validation and clinical evaluation of a SARS-CoV-2 surrogate virus neutralisation test (sVNT)Emerging Microbes and Infections2020116
50BCKDH: The Missing Link in Apicomplexan Mitochondrial Metabolism Is Required for Full Virulence of Toxoplasma gondii and Plasmodium bergheiPLoS Pathogens2014115