| # | Title | Journal | Year | Citations |
|---|
| 1 | Effect of Robotic-Assisted vs Conventional Laparoscopic Surgery on Risk of Conversion to Open Laparotomy Among Patients Undergoing Resection for Rectal Cancer | JAMA - Journal of the American Medical Association | 2017 | 891 |
| 2 | Bladder cancer | Nature Reviews Disease Primers | 2017 | 590 |
| 3 | Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies | Clinical Cancer Research | 2014 | 561 |
| 4 | Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases | JAMA Oncology | 2017 | 376 |
| 5 | Diagnosis and treatment of melanoma. European consensus-based interdisciplinary guideline – Update 2016 | European Journal of Cancer | 2016 | 330 |
| 6 | POT1 loss-of-function variants predispose to familial melanoma | Nature Genetics | 2014 | 319 |
| 7 | Replication and validation of higher order models demonstrated that a summary score for the EORTC QLQ-C30 is robust | Journal of Clinical Epidemiology | 2016 | 306 |
| 8 | Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade | Science Translational Medicine | 2018 | 288 |
| 9 | New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk | Nature Communications | 2016 | 245 |
| 10 | The ERK and JNK pathways in the regulation of metabolic reprogramming | Oncogene | 2019 | 244 |
| 11 | Systematic Review of Synthetic Computed Tomography Generation Methodologies for Use in Magnetic Resonance Imaging–Only Radiation Therapy | International Journal of Radiation Oncology Biology Physics | 2018 | 235 |
| 12 | World Endoscopy Organization Consensus Statements on Post-Colonoscopy and Post-Imaging Colorectal Cancer | Gastroenterology | 2018 | 221 |
| 13 | Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma | Nature Genetics | 2015 | 218 |
| 14 | ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells | Blood | 2016 | 214 |
| 15 | A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study | Leukemia | 2016 | 200 |
| 16 | Signatures of tumour immunity distinguish Asian and non-Asian gastric adenocarcinomas | Gut | 2015 | 197 |
| 17 | Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis | Nature Communications | 2020 | 193 |
| 18 | The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery | International Journal of Colorectal Disease | 2014 | 186 |
| 19 | HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials | Journal of Pathology | 2016 | 185 |
| 20 | International standards for the analysis of quality-of-life and patient-reported outcome endpoints in cancer randomised controlled trials: recommendations of the SISAQOL Consortium | Lancet Oncology, The | 2020 | 180 |
| 21 | Host Inflammatory Response to Mosquito Bites Enhances the Severity of Arbovirus Infection | Immunity | 2016 | 178 |
| 22 | Anti–PD-1/anti–CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8+T cell trafficking | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 165 |
| 23 | Variation in genomic landscape of clear cell renal cell carcinoma across Europe | Nature Communications | 2014 | 158 |
| 24 | Analysing data from patient-reported outcome and quality of life endpoints for cancer clinical trials: a start in setting international standards | Lancet Oncology, The | 2016 | 158 |
| 25 | FGFR2 amplification has prognostic significance in gastric cancer: results from a large international multicentre study | British Journal of Cancer | 2014 | 154 |
| 26 | mTOR Regulation of Glycolytic Metabolism in T Cells | Frontiers in Cell and Developmental Biology | 2018 | 142 |
| 27 | Investigating the poor outcomes ofBRAF-mutant advanced colorectal cancer: analysis from 2530 patients in randomised clinical trials | Annals of Oncology | 2017 | 132 |
| 28 | In vivomodels in breast cancer research: progress, challenges and future directions | DMM Disease Models and Mechanisms | 2017 | 131 |
| 29 | Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness | Nature Communications | 2016 | 127 |
| 30 | Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk | American Journal of Human Genetics | 2020 | 124 |
| 31 | Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer | Nature Communications | 2016 | 122 |
| 32 | Electronic Systems for Patients to Report and Manage Side Effects of Cancer Treatment: Systematic Review | Journal of Medical Internet Research | 2019 | 121 |
| 33 | Cumulative Burden of Colorectal Cancer–Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer | Gastroenterology | 2020 | 110 |
| 34 | Evidence that tissue resident human enthesis γδT-cells can produce IL-17A independently of IL-23R transcript expression | Annals of the Rheumatic Diseases | 2019 | 109 |
| 35 | High hospital research participation and improved colorectal cancer survival outcomes: a population-based study | Gut | 2017 | 107 |
| 36 | Minimal residual disease is an independent predictor for 10-year survival in CLL | Blood | 2016 | 106 |
| 37 | Genome-wide association study identifies multiple risk loci for renal cell carcinoma | Nature Communications | 2017 | 106 |
| 38 | Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor | Nature Genetics | 2017 | 105 |
| 39 | Germline MC1R status influences somatic mutation burden in melanoma | Nature Communications | 2016 | 103 |
| 40 | RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells | Stem Cell Reports | 2017 | 100 |
| 41 | Systemic neutrophil-to-lymphocyte ratio in colorectal cancer: the relationship to patient survival, tumour biology and local lymphocytic response to tumour | British Journal of Cancer | 2015 | 99 |
| 42 | Beyond maximum grade: modernising the assessment and reporting of adverse events in haematological malignancies | Lancet Haematology,the | 2018 | 97 |
| 43 | Blimp‐1 homolog Hobit identifies effector‐type lymphocytes in humans | European Journal of Immunology | 2015 | 94 |
| 44 | Practice-changing radiation therapy trials for the treatment of cancer: where are we 150 years after the birth of Marie Curie? | British Journal of Cancer | 2018 | 92 |
| 45 | The prognostic significance of tumour–stroma ratio in oestrogen receptor-positive breast cancer | British Journal of Cancer | 2014 | 90 |
| 46 | The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 89 |
| 47 | Patient-reported outcomes in cancer survivors: a population-wide cross-sectional study | Supportive Care in Cancer | 2017 | 87 |
| 48 | Can we Save the rectum by watchful waiting or TransAnal microsurgery following (chemo) Radiotherapy versus Total mesorectal excision for early REctal Cancer (STAR-TREC study)?: protocol for a multicentre, randomised feasibility study | BMJ Open | 2017 | 87 |
| 49 | Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways | Nature Communications | 2018 | 87 |
| 50 | Cross-laboratory validation of the OncoScan® FFPE Assay, a multiplex tool for whole genome tumour profiling | BMC Medical Genomics | 2015 | 84 |
