| # | Title | Journal | Year | Citations |
|---|
| 1 | Why do cancers have high aerobic glycolysis? | Nature Reviews Cancer | 2004 | 4,181 |
| 2 | A microenvironmental model of carcinogenesis | Nature Reviews Cancer | 2008 | 651 |
| 3 | Ovarian Teratomas: Tumor Types and Imaging Characteristics | Radiographics | 2001 | 506 |
| 4 | Model observers for assessment of image quality. | Proceedings of the National Academy of Sciences of the United States of America | 1993 | 479 |
| 5 | Noise properties of the EM algorithm. I. Theory | Physics in Medicine and Biology | 1994 | 373 |
| 6 | Addition of a channel mechanism to the ideal-observer model | Journal of the Optical Society of America A: Optics and Image Science, and Vision | 1987 | 367 |
| 7 | Frequency and Costs of Diagnostic Imaging in Office Practice — A Comparison of Self-Referring and Radiologist-Referring Physicians | New England Journal of Medicine | 1990 | 365 |
| 8 | Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer | British Journal of Cancer | 2007 | 301 |
| 9 | Human- and model-observer performance in ramp-spectrum noise: effects of regularization and object variability | Journal of the Optical Society of America A: Optics and Image Science, and Vision | 2001 | 292 |
| 10 | MRI-guided noninvasive ultrasound surgery | Medical Physics | 1993 | 288 |
| 11 | Local drug and gene delivery through microbubbles | Progress in Cardiovascular Diseases | 2001 | 276 |
| 12 | Glycolysis in cancer: A potential target for therapy | International Journal of Biochemistry and Cell Biology | 2007 | 265 |
| 13 | A Cellular Automaton Model of Early Tumor Growth and Invasion: The Effects of Native Tissue Vascularity and Increased Anaerobic Tumor Metabolism | Journal of Theoretical Biology | 2001 | 239 |
| 14 | A transparent access chamber for the rat dorsal skin fold | Microvascular Research | 1979 | 234 |
| 15 | Current perspectives in medical image perception | Attention, Perception, and Psychophysics | 2010 | 231 |
| 16 | Bone marrow edema pattern in advanced hip osteoarthritis: quantitative assessment with magnetic resonance imaging and correlation with clinical examination, radiographic findings, and histopathology | Skeletal Radiology | 2008 | 217 |
| 17 | Objective assessment of image quality III ROC metrics, ideal observers, and likelihood-generating functions | Journal of the Optical Society of America A: Optics and Image Science, and Vision | 1998 | 210 |
| 18 | The glycolytic phenotype in carcinogenesis and tumor invasion: insights through mathematical models | Cancer Research | 2003 | 210 |
| 19 | Pneumomediastinum Revisited | Radiographics | 2000 | 208 |
| 20 | Mathematical oncology: Cancer summed up | Nature | 2003 | 201 |
| 21 | Visual scanning patterns of radiologists searching mammograms | Academic Radiology | 1996 | 197 |
| 22 | Long Radiology Workdays Reduce Detection and Accommodation Accuracy | Journal of the American College of Radiology | 2010 | 197 |
| 23 | Effect of noise correlation on detectability of disk signals in medical imaging | Journal of the Optical Society of America A: Optics and Image Science, and Vision | 1985 | 188 |
| 24 | Percutaneous sclerotherapy of lymphangiomas. | Radiology | 1995 | 179 |
| 25 | Early Increases in Breast Tumor Xenograft Water Mobility in Response to Paclitaxel Therapy Detected by Non-Invasive Diffusion Magnetic Resonance Imaging | Neoplasia | 1999 | 178 |
| 26 | Metabolic changes during carcinogenesis: Potential impact on invasiveness | Journal of Theoretical Biology | 2007 | 164 |
| 27 | Imaging of musculoskeletal soft tissue infections | Skeletal Radiology | 2010 | 159 |
| 28 | Gene Delivery Using Ultrasound Contrast Agents | Echocardiography | 2001 | 157 |
| 29 | In vitro studies of a new thrombus-specific ultrasound contrast agent | American Journal of Cardiology | 1998 | 154 |
| 30 | Treatment of malignant brain tumors with focused ultrasound hyperthermia and radiation: results of a phase I trial | Journal of Neuro-Oncology | 1991 | 151 |
| 31 | Diagnostic Accuracy and Image Quality Using a Digital Camera for Teledermatology | Telemedicine and E-Health | 1999 | 148 |
| 32 | Dual-Energy X-Ray Absorptiometry Is a Valid Tool for Assessing Skeletal Muscle Mass in Older Women , | Journal of Nutrition | 2007 | 147 |
| 33 | The role of acidity in solid tumour growth and invasion | Journal of Theoretical Biology | 2005 | 140 |
| 34 | T2 mapping from highly undersampled data by reconstruction of principal component coefficient maps using compressed sensing | Magnetic Resonance in Medicine | 2012 | 134 |
| 35 | Hotelling trace criterion and its correlation with human-observer performance | Journal of the Optical Society of America A: Optics and Image Science, and Vision | 1987 | 133 |
| 36 | Slit-scanning confocal microendoscope for high-resolution in vivo imaging | Applied Optics | 1999 | 132 |
| 37 | Nanoparticle drug delivery system for intravenous delivery of topoisomerase inhibitors | Journal of Controlled Release | 2003 | 122 |
| 38 | Predictive oncology: A review of multidisciplinary, multiscale in silico modeling linking phenotype, morphology and growth | NeuroImage | 2007 | 120 |
| 39 | Signals induced in semiconductor gamma-ray imaging detectors | Journal of Applied Physics | 1999 | 117 |
| 40 | Ideal-observer computation in medical imaging with use of Markov-chain Monte Carlo techniques | Journal of the Optical Society of America A: Optics and Image Science, and Vision | 2003 | 108 |
| 41 | Design and demonstration of a miniature catheter for a confocal microendoscope | Applied Optics | 2004 | 108 |
| 42 | SemiSPECT: A small-animal single-photon emission computed tomography (SPECT) imager based on eight cadmium zinc telluride (CZT) detector arrays | Medical Physics | 2006 | 107 |
| 43 | Digital Radiography Image Quality: Image Acquisition | Journal of the American College of Radiology | 2007 | 93 |
| 44 | The utility of in-phase/opposed-phase imaging in differentiating malignancy from acute benign compression fractures of the spine | American Journal of Neuroradiology | 2006 | 93 |
| 45 | Radiologic History Exhibit | Radiographics | 2000 | 89 |
| 46 | Routine Surgical Telepathology in the Department of Veterans Affairs: Experience-Related Improvements in Pathologist Performance in 2200 Cases | Telemedicine and E-Health | 1999 | 88 |
| 47 | Radionuclide Lymphangioscintigraphy in the Evaluation of Peripheral Lymphedema | Clinical Nuclear Medicine | 2000 | 87 |
| 48 | Do Long Radiology Workdays Affect Nodule Detection in Dynamic CT Interpretation? | Journal of the American College of Radiology | 2012 | 86 |
| 49 | Influence of film and monitor display luminance on observer performance and visual search | Academic Radiology | 1999 | 84 |
| 50 | Ultrasound for the detection of foreign bodies | Annals of Emergency Medicine | 1991 | 82 |
