| # | Title | Journal | Year | Citations |
|---|
| 1 | The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3 | Nature Genetics | 2001 | 2,964 |
| 2 | A Polymorphism* in the 5 ′ Flanking Region of the CD14 Gene Is Associated with Circulating Soluble CD14 Levels and with Total Serum Immunoglobulin E | American Journal of Respiratory Cell and Molecular Biology | 1999 | 785 |
| 3 | Mutations in FOXC2 (MFH-1), a Forkhead Family Transcription Factor, Are Responsible for the Hereditary Lymphedema-Distichiasis Syndrome | American Journal of Human Genetics | 2000 | 549 |
| 4 | Poor airway function in early infancy and lung function by age 22 years: a non-selective longitudinal cohort study | Lancet, The | 2007 | 507 |
| 5 | Epidemiology of Physician-Diagnosed Allergic Rhinitis in Childhood | Pediatrics | 1994 | 365 |
| 6 | Myocardial dysfunction after resuscitation from cardiac arrest: An example of global myocardial stunning | Journal of the American College of Cardiology | 1996 | 332 |
| 7 | THE TUCSON CHILDREN'S RESPIRATORY STUDY | American Journal of Epidemiology | 1989 | 318 |
| 8 | Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity? | Nature Reviews Immunology | 2019 | 269 |
| 9 | Temporal and Distinct TGFβ Ligand Requirements during Mouse and Avian Endocardial Cushion Morphogenesis | Developmental Biology | 2002 | 262 |
| 10 | Exome sequencing reveals new causal mutations in children with epileptic encephalopathies | Epilepsia | 2013 | 250 |
| 11 | Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons | Neuron | 1995 | 242 |
| 12 | CD4+CD25+FoxP3+ regulatory T cells suppress Mycobacterium tuberculosis immunity in patients with active disease | Clinical Immunology | 2007 | 241 |
| 13 | Epidermal growth factor reduces the development of necrotizing enterocolitis in a neonatal rat model | American Journal of Physiology - Renal Physiology | 2002 | 229 |
| 14 | Bystander cardiopulmonary resuscitation. Is ventilation necessary? | Circulation | 1993 | 228 |
| 15 | Intestinal barrier failure during experimental necrotizing enterocolitis: protective effect of EGF treatment | American Journal of Physiology - Renal Physiology | 2006 | 227 |
| 16 | THE TUCSON CHILDREN'S RESPIRATORY STUDY | American Journal of Epidemiology | 1989 | 219 |
| 17 | Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of hsp90-binding agents | Clinical Cancer Research | 2000 | 217 |
| 18 | Clinical and biochemical spectrum of patients with RSH/Smith-Lemli-Opitz syndrome and abnormal cholesterol metabolism | American Journal of Medical Genetics Part A | 1997 | 208 |
| 19 | Smallpox Vaccination: A Review, Part II. Adverse Events | Clinical Infectious Diseases | 2003 | 205 |
| 20 | Higher Survival Rates Among Younger Patients After Pediatric Intensive Care Unit Cardiac Arrests | Pediatrics | 2006 | 199 |
| 21 | Tumor-derived CD4+CD25+ regulatory T cell suppression of dendritic cell function involves TGF-β and IL-10 | Cancer Immunology, Immunotherapy | 2006 | 190 |
| 22 | Altered Cholesterol Metabolism in Niemann-Pick Type C1 Mouse Brains Affects Mitochondrial Function | Journal of Biological Chemistry | 2005 | 179 |
| 23 | Branched Chain Fatty Acids Reduce the Incidence of Necrotizing Enterocolitis and Alter Gastrointestinal Microbial Ecology in a Neonatal Rat Model | PLoS ONE | 2011 | 168 |
| 24 | Bifidobacterium bifidum improves intestinal integrity in a rat model of necrotizing enterocolitis | American Journal of Physiology - Renal Physiology | 2009 | 160 |
| 25 | The National Niemann–Pick C1 disease database: Report of clinical features and health problems | American Journal of Medical Genetics, Part A | 2007 | 158 |
| 26 | 1,25-Dihydroxyvitamin D3/VDR-mediated induction of FGF23 as well as transcriptional control of other bone anabolic and catabolic genes that orchestrate the regulation of phosphate and calcium mineral metabolism | Journal of Steroid Biochemistry and Molecular Biology | 2007 | 157 |
| 27 | Cord blood 25-hydroxyvitamin D levels are associated with aeroallergen sensitization in children from Tucson, Arizona | Journal of Allergy and Clinical Immunology | 2011 | 155 |
| 28 | Aberrant pH of Melanosomes in Pink-Eyed Dilution (p) Mutant Melanocytes | Journal of Investigative Dermatology | 2000 | 152 |
| 29 | Stressed apoptotic tumor cells stimulate dendritic cells and induce specific cytotoxic T cells | Blood | 2002 | 150 |
| 30 | Invasion and metastasis of a mammary tumor involves TGF-? signaling | International Journal of Cancer | 2001 | 148 |
| 31 | A Guide to Pain Assessment and Management in the Neonate | Current Emergency and Hospital Medicine Reports | 2016 | 148 |
| 32 | Stressed apoptotic tumor cells express heat shock proteins and elicit tumor-specific immunity | Blood | 2001 | 145 |
| 33 | Elements of morphology: Standard terminology for the head and face | American Journal of Medical Genetics, Part A | 2009 | 145 |
| 34 | Erythropoietin Concentrations and Neurodevelopmental Outcome in Preterm Infants | Pediatrics | 2006 | 143 |
| 35 | Toxic Stress: Effects, Prevention and Treatment | Children | 2014 | 141 |
| 36 | Imatinib Mesylate Inhibits CD4+CD25+ Regulatory T Cell Activity and Enhances Active Immunotherapy against BCR-ABL− Tumors | Journal of Immunology | 2008 | 140 |
| 37 | Transcription of paternal Y-linked genes in the human zygote as early as the pronucleate stage | Zygote | 1994 | 135 |
| 38 | Role of Chlamydia trachomatis in Perinatal Infection | Clinical Infectious Diseases | 1983 | 131 |
| 39 | Cystic Fibrosis Newborn Screening: Impact on Reproductive Behavior and Implications for Genetic Counseling | Pediatrics | 1998 | 131 |
| 40 | The role of intestinal epithelial barrier function in the development of NEC | Tissue Barriers | 2015 | 129 |
| 41 | Geldanamycin-stimulated destabilization of mutated p53 is mediated by the proteasome in vivo | Oncogene | 1997 | 126 |
| 42 | Extracorporeal membrane oxygenation (ECMO) for critically ill adults in the emergency department: history, current applications, and future directions | Critical Care | 2015 | 126 |
| 43 | The Need for Ventilatory Support During Bystander CPR | Annals of Emergency Medicine | 1995 | 124 |
| 44 | Epidermal growth factor reduces intestinal apoptosis in an experimental model of necrotizing enterocolitis | American Journal of Physiology - Renal Physiology | 2005 | 124 |
| 45 | The immunological case for staying active during the COVID-19 pandemic | Brain, Behavior, and Immunity | 2020 | 123 |
| 46 | Hospitalizations and Deaths Due toSalmonellaInfections, FoodNet, 1996–1999 | Clinical Infectious Diseases | 2004 | 121 |
| 47 | Risk Factors for Developing Wheezing and Asthma in Childhood | Pediatric Clinics of North America | 1992 | 119 |
| 48 | Dendritic Cell-Specific Disruption of TGF-β Receptor II Leads to Altered Regulatory T Cell Phenotype and Spontaneous Multiorgan Autoimmunity | Journal of Immunology | 2012 | 119 |
| 49 | Primary Care Pediatricians' Satisfaction with Subspecialty Care, Perceived Supply, and Barriers to Care | Journal of Pediatrics | 2010 | 116 |
| 50 | Lactoferrin protects neonatal rats from gut-related systemic infection | American Journal of Physiology - Renal Physiology | 2001 | 115 |
