Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina | Molecular Therapy | 2011 | 196 |
Endothelin-1 gene regulation | FASEB Journal | 2011 | 150 |
Engineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer | Molecular Therapy | 2011 | 139 |
AAV capsid structure and cell interactions | Methods in Molecular Biology | 2011 | 123 |
Silencing of soybean seed storage proteins results in a rebalanced protein composition preserving seed protein content without major collateral changes in the metabolome and transcriptome | Plant Physiology | 2011 | 103 |
The circadian clock in the kidney | Journal of the American Society of Nephrology: JASN | 2011 | 94 |
Two rotary motors in F-ATP synthase are elastically coupled by a flexible rotor and a stiff stator stalk | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 83 |
Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies | Bioorganic and Medicinal Chemistry | 2011 | 82 |
Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery | Human Molecular Genetics | 2011 | 81 |
Intramolecular proton shuttle supports not only catalytic but also noncatalytic function of carbonic anhydrase II | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 81 |
Phase shift in hippocampal circadian rhythm during the latent period of epileptic rats | BMC Neuroscience | 2011 | 78 |
MTF-1-mediated repression of the zinc transporter Zip10 is alleviated by zinc restriction | PLoS ONE | 2011 | 74 |
Ascaroside expression in Caenorhabditis elegans is strongly dependent on diet and developmental stage | PLoS ONE | 2011 | 68 |
Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV | Journal of Medicinal Chemistry | 2011 | 65 |
Sensitivity analysis of an image-based solid tumor computational model with heterogeneous vasculature and porosity | Annals of Biomedical Engineering | 2011 | 64 |
Hierarchical alignment and full resolution pattern recognition of 2D NMR spectra: application to nematode chemical ecology | Analytical Chemistry | 2011 | 57 |
Chemical rescue of enzymes: proton transfer in mutants of human carbonic anhydrase II | Journal of the American Chemical Society | 2011 | 54 |
Neutron structure of human carbonic anhydrase II: a hydrogen-bonded water network "switch" is observed between pH 7.8 and 10.0 | Biochemistry | 2011 | 48 |
The dichloroacetate dilemma: environmental hazard versus therapeutic goldmine--both or neither? | Environmental Health Perspectives | 2011 | 47 |
Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms | Bioorganic and Medicinal Chemistry | 2011 | 45 |
Catalysis and pH control by membrane-associated carbonic anhydrase IX in MDA-MB-231 breast cancer cells | Journal of Biological Chemistry | 2011 | 44 |
Transport activity of the sodium bicarbonate cotransporter NBCe1 is enhanced by different isoforms of carbonic anhydrase | PLoS ONE | 2011 | 33 |
Role of helix-loop-helix proteins during differentiation of erythroid cells | Molecular and Cellular Biology | 2011 | 31 |
The Escherichia coli clamp loader can actively pry open the β-sliding clamp | Journal of Biological Chemistry | 2011 | 29 |
Non-template functions of viral RNA in picornavirus replication | Current Opinion in Virology | 2011 | 28 |