# | Title | Journal | Year | Citations |
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1 | DNA methylation and human disease | Nature Reviews Genetics | 2005 | 2,449 |
2 | The family Parvoviridae | Archives of Virology | 2014 | 555 |
3 | Arrangement of rhodopsin transmembrane α-helices | Nature | 1997 | 486 |
4 | ATF4-dependent transcription mediates signaling of amino acid limitation | Trends in Endocrinology and Metabolism | 2009 | 469 |
5 | The regulation of neutral amino acid transport in mammalian cells | BBA - Biomembranes | 1983 | 433 |
6 | MicroRNA-125b Confers the Resistance of Breast Cancer Cells to Paclitaxel through Suppression of Pro-apoptotic Bcl-2 Antagonist Killer 1 (Bak1) Expression | Journal of Biological Chemistry | 2010 | 370 |
7 | Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells | Trends in Endocrinology and Metabolism | 2017 | 356 |
8 | Resolution of complex tissue microarchitecture using the diffusion orientation transform (DOT) | NeuroImage | 2006 | 346 |
9 | Palaeotemperature trend for Precambrian life inferred from resurrected proteins | Nature | 2008 | 338 |
10 | A blend of small molecules regulates both mating and development in Caenorhabditis elegans | Nature | 2008 | 335 |
11 | DNA Methylation Inhibitor 5-Aza-2′-Deoxycytidine Induces Reversible Genome-Wide DNA Damage That Is Distinctly Influenced by DNA Methyltransferases 1 and 3B | Molecular and Cellular Biology | 2008 | 321 |
12 | Hyperpolarized 13C MRI: Path to Clinical Translation in Oncology | Neoplasia | 2019 | 316 |
13 | Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol | Molecular Cancer | 2010 | 307 |
14 | Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease | EMBO Molecular Medicine | 2013 | 270 |
15 | α2,3 and α2,6 N-Linked Sialic Acids Facilitate Efficient Binding and Transduction by Adeno-Associated Virus Types 1 and 6 | Journal of Virology | 2006 | 268 |
16 | Manganese Superoxide Dismutase Attenuates Cisplatin-Induced Renal Injury | Journal of the American Society of Nephrology: JASN | 2001 | 243 |
17 | 5′ cloverleaf in poliovirus RNA is a cis-acting replication element required for negative-strand synthesis | EMBO Journal | 2001 | 242 |
18 | Specific Loss of Histone H3 Lysine 9 Trimethylation and HP1γ/Cohesin Binding at D4Z4 Repeats Is Associated with Facioscapulohumeral Dystrophy (FSHD) | PLoS Genetics | 2009 | 234 |
19 | Nucleotide sequence evidence for rapid genotypic shifts in the bovine mitochondrial DNA D-loop | Nature | 1983 | 231 |
20 | Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles | Molecular Therapy | 2008 | 224 |
21 | The story so far: molecular regulation of the heme oxygenase-1 gene in renal injury | American Journal of Physiology - Renal Physiology | 2004 | 216 |
22 | DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function | Human Molecular Genetics | 2008 | 216 |
23 | Amino acid transport in isolated rat hepatocytes | Journal of Membrane Biology | 1982 | 215 |
24 | Dithiocarbamates Strongly Inhibit Carbonic Anhydrases and Show Antiglaucoma Action in Vivo | Journal of Medicinal Chemistry | 2012 | 211 |
25 | A Modular Library of Small Molecule Signals Regulates Social Behaviors in Caenorhabditis elegans | PLoS Biology | 2012 | 208 |
26 | A novel tensor distribution model for the diffusion-weighted MR signal | NeuroImage | 2007 | 204 |
27 | A Small Molecule Inhibitor, 1,2,4,5-Benzenetetraamine Tetrahydrochloride, Targeting the Y397 Site of Focal Adhesion Kinase Decreases Tumor Growth | Journal of Medicinal Chemistry | 2008 | 204 |
28 | Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency | Chemical Communications | 2010 | 200 |
29 | Differential expression of largemouth bass (Micropterus salmoides) estrogen receptor isotypes alpha, beta, and gamma by estradiol | Molecular and Cellular Endocrinology | 2004 | 199 |
30 | Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy Vector | Journal of Virology | 2007 | 199 |
31 | Molecular Biology of Mammalian Amino Acid Transporters | Annual Review of Biochemistry | 1996 | 197 |
32 | Entrapment of Carbon Dioxide in the Active Site of Carbonic Anhydrase II | Journal of Biological Chemistry | 2008 | 197 |
33 | Asparagine synthetase: Function, structure, and role in disease | Journal of Biological Chemistry | 2017 | 197 |
34 | Single Amino Acid Changes Can Influence Titer, Heparin Binding, and Tissue Tropism in Different Adeno-Associated Virus Serotypes | Journal of Virology | 2006 | 194 |
35 | Endothelin‐1 gene regulation | FASEB Journal | 2011 | 189 |
36 | Structural annotation of human carbonic anhydrases | Journal of Enzyme Inhibition and Medicinal Chemistry | 2013 | 189 |
37 | Recent Advances in Mammalian Amino Acid Transport | Annual Review of Nutrition | 1993 | 188 |
38 | A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 187 |
39 | Structure of the Maize Streak Virus Geminate Particle | Virology | 2001 | 180 |
40 | Carbonic Anhydrases: Role in pH Control and Cancer | Metabolites | 2018 | 180 |
41 | Engineering Liver-detargeted AAV9 Vectors for Cardiac and Musculoskeletal Gene Transfer | Molecular Therapy | 2011 | 179 |
42 | A metastable liquid precursor phase of calcium carbonate and its interactions with polyaspartate | Faraday Discussions | 2012 | 173 |
43 | A comparison of the estrogenic potencies of estradiol, ethynylestradiol, diethylstilbestrol, nonylphenol and methoxychlor in vivo and in vitro | Aquatic Toxicology | 2002 | 172 |
44 | Anticonvulsant/antiepileptic carbonic anhydrase inhibitors: a patent review | Expert Opinion on Therapeutic Patents | 2013 | 172 |
45 | Effects of altered gene order or orientation of the locus control region on human β-globin gene expression in mice | Nature | 1999 | 170 |
46 | CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis | Molecular Biology of the Cell | 2013 | 170 |
47 | Structurally Mapping the Diverse Phenotype of Adeno-Associated Virus Serotype 4 | Journal of Virology | 2006 | 165 |
48 | Adeno-Associated Virus Type 2 Contains an Integrin α5β1 Binding Domain Essential for Viral Cell Entry | Journal of Virology | 2006 | 164 |
49 | Structural Insight into the Unique Properties of Adeno-Associated Virus Serotype 9 | Journal of Virology | 2012 | 163 |
50 | Comparative estrogenicity of estradiol, ethynyl estradiol and diethylstilbestrol in an in vivo, male sheepshead minnow (Cyprinodon variegatus), vitellogenin bioassay | Aquatic Toxicology | 2000 | 162 |