| # | Title | Journal | Year | Citations |
|---|
| 1 | Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 1,048 |
| 2 | Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates | Nature Genetics | 2009 | 800 |
| 3 | Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization | Nature Medicine | 2002 | 635 |
| 4 | STUDIES ON THE MECHANISM OF ACTION OF A NEW Ca2+ ANTAGONIST, 8‐(N,N‐DIETHYLAMINO)OCTYL 3,4,5‐TRIMETHOXYBENZOATE HYDROCHLORIDE IN SMOOTH AND SKELETAL MUSCLES | British Journal of Pharmacology | 1975 | 341 |
| 5 | Fractalkine and CX3CR1 regulate hippocampal neurogenesis in adult and aged rats | Neurobiology of Aging | 2011 | 317 |
| 6 | Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia | Psychopharmacology | 2004 | 311 |
| 7 | Hyperglycemia-Induced Reactive Oxygen Species Toxicity to Endothelial Cells Is Dependent on Paracrine Mediators | Diabetes | 2008 | 284 |
| 8 | An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the α7 subtype | Neuroscience Letters | 1996 | 264 |
| 9 | Selective α 7 -nicotinic agonists normalize inhibition of auditory response in DBA mice | Psychopharmacology | 1998 | 256 |
| 10 | A CYTOCHEMICAL STUDY OF THE LOCALIZATION OF CARBONIC ANHYDRASE IN THE NERVOUS SYSTEM | Journal of Neurochemistry | 1962 | 247 |
| 11 | Stromal cell–derived factor 1 promotes angiogenesis via a heme oxygenase 1–dependent mechanism | Journal of Experimental Medicine | 2007 | 246 |
| 12 | Ischemic Vascular Damage Can Be Repaired by Healthy, but Not Diabetic, Endothelial Progenitor Cells | Diabetes | 2007 | 246 |
| 13 | Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding | American Journal of Physiology - Regulatory Integrative and Comparative Physiology | 2008 | 242 |
| 14 | Evidence That Oxidative Stress Is Associated with the Pathophysiology of Inherited Hydrocephalus in the H-Tx Rat Model | Experimental Neurology | 1999 | 241 |
| 15 | Cigarette Smoking and Pregnancy I: Ovarian, Uterine and Placental Effects | Placenta | 1999 | 239 |
| 16 | Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: Advantages and limitations | Biochemical Pharmacology | 2011 | 236 |
| 17 | Comparative pharmacology of rat and human α7 nAChR conducted with net charge analysis | British Journal of Pharmacology | 2002 | 226 |
| 18 | Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects | Nature Communications | 2019 | 226 |
| 19 | Neuron-Specific Transduction in the Rat Septohippocampal or Nigrostriatal Pathway by Recombinant Adeno-associated Virus Vectors | Experimental Neurology | 1998 | 225 |
| 20 | Rapamycin: An anti-cancer immunosuppressant? | Critical Reviews in Oncology/Hematology | 2005 | 223 |
| 21 | ShK-Dap22, a Potent Kv1.3-specific Immunosuppressive Polypeptide | Journal of Biological Chemistry | 1998 | 222 |
| 22 | Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock | Journal of Experimental Medicine | 2009 | 219 |
| 23 | Analysis of mecamylamine stereoisomers on human nicotinic receptor subtypes | Journal of Pharmacology and Experimental Therapeutics | 2001 | 211 |
| 24 | Pharmacological evaluation of a new Ca2+ antagonist, 8-(N,N-diethylamino)-octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8): Studies in smooth muscles | European Journal of Pharmacology | 1974 | 207 |
| 25 | Pigment Epithelium-derived Factor Inhibits Angiogenesis via Regulated Intracellular Proteolysis of Vascular Endothelial Growth Factor Receptor 1 | Journal of Biological Chemistry | 2006 | 204 |
| 26 | A novel ATG4B antagonist inhibits autophagy and has a negative impact on osteosarcoma tumors | Autophagy | 2014 | 190 |
| 27 | Leptin resistance: a prediposing factor for diet-induced obesity | American Journal of Physiology - Regulatory Integrative and Comparative Physiology | 2009 | 176 |
| 28 | DQAsomes: a novel potential drug and gene delivery system made from Dequalinium | Pharmaceutical Research | 1998 | 170 |
| 29 | Chemokine receptor expression in cultured glia and rat experimental allergic encephalomyelitis | Journal of Neuroimmunology | 1998 | 160 |
| 30 | Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis | Cell | 2019 | 159 |
| 31 | Carbonic anhydrase: General perspective and advances in glaucoma research | Drug Development Research | 1987 | 157 |
| 32 | NF-κB-dependent fractalkine induction in rat aortic endothelial cells stimulated by IL-1β, TNF-α, and LPS | Journal of Leukocyte Biology | 2000 | 157 |
| 33 | Merging old and new perspectives on nicotinic acetylcholine receptors | Biochemical Pharmacology | 2014 | 154 |
| 34 | Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia | Nature Communications | 2014 | 149 |
| 35 | The role of growth factors in the pathogenesis of diabetic retinopathy | Expert Opinion on Investigational Drugs | 2004 | 148 |
| 36 | Inflammation in the pathogenesis of microvascular complications in diabetes | Frontiers in Endocrinology | 2012 | 146 |
| 37 | ACE2 and Ang-(1-7) Confer Protection Against Development of Diabetic Retinopathy | Molecular Therapy | 2012 | 143 |
| 38 | Innate Predator Odor Aversion Driven by Parallel Olfactory Subsystems that Converge in the Ventromedial Hypothalamus | Current Biology | 2015 | 138 |
| 39 | Dose and Promoter Effects of Adeno-Associated Viral Vector for Green Fluorescent Protein Expression in the Rat Brain | Experimental Neurology | 2002 | 137 |
| 40 | The antinociceptive effects of α7 nicotinic agonists in an acute pain model | Neuropharmacology | 2000 | 130 |
| 41 | The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory | Immunity | 2018 | 128 |
| 42 | Acceleration of β-receptor desensitization in combined administration of antidepressants and phenoxybenzamine | Nature | 1981 | 122 |
| 43 | Prevention of 6-hydroxydopamine-induced rotational behavior by BDNF somatic gene transfer | Brain Research | 1999 | 121 |
| 44 | Chemokines and their receptors in neurobiology: perspectives in physiology and homeostasis | Journal of Neuroimmunology | 2000 | 119 |
| 45 | Recent Smell Loss Is the Best Predictor of COVID-19 Among Individuals With Recent Respiratory Symptoms | Chemical Senses | 2021 | 119 |
| 46 | Enzymatic glucose detection using ZnO nanorods on the gate region of AlGaN∕GaN high electron mobility transistors | Applied Physics Letters | 2007 | 117 |
| 47 | Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3 | Gene Expression Patterns | 2003 | 113 |
| 48 | α7 Receptor-selective agonists and modes of α7 receptor activation | European Journal of Pharmacology | 2000 | 107 |
| 49 | Hydroxy Metabolites of the Alzheimer's Drug Candidate 3-[(2,4-Dimethoxy)Benzylidene]-Anabaseine Dihydrochloride (GTS-21): Their Molecular Properties, Interactions with Brain Nicotinic Receptors, and Brain Penetration | Molecular Pharmacology | 2004 | 106 |
| 50 | Analysis of 3-(4-hydroxy, 2-Methoxybenzylidene)anabaseine selectivity and activity at human and rat alpha-7 nicotinic receptors | Journal of Pharmacology and Experimental Therapeutics | 1998 | 105 |
