| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Treatment of Aspergillosis: Clinical Practice Guidelines of the Infectious Diseases Society of America | Clinical Infectious Diseases | 2008 | 2,432 |
| 3 | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research | PLoS Biology | 2020 | 2,209 |
| 4 | Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging | Science | 2005 | 1,847 |
| 5 | GRADE guidelines: 7. Rating the quality of evidence—inconsistency | Journal of Clinical Epidemiology | 2011 | 1,705 |
| 6 | Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System | Circulation Research | 2020 | 1,478 |
| 7 | Type 1 diabetes: new perspectives on disease pathogenesis and treatment | Lancet, The | 2001 | 1,244 |
| 8 | Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes | Nature | 1993 | 1,125 |
| 9 | Lack of Improvement in Renal Allograft Survival Despite a Marked Decrease in Acute Rejection Rates Over the Most Recent Era | American Journal of Transplantation | 2004 | 1,072 |
| 10 | Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 | PLoS Biology | 2020 | 1,069 |
| 11 | Prognostic Value of Usual Gait Speed in Well‐Functioning Older People—Results from the Health, Aging and Body Composition Study | Journal of the American Geriatrics Society | 2005 | 940 |
| 12 | RNA mis-splicing in disease | Nature Reviews Genetics | 2016 | 935 |
| 13 | Effects of beverage alcohol price and tax levels on drinking: a meta‐analysis of 1003 estimates from 112 studies | Addiction | 2009 | 930 |
| 14 | An overview of global rice production, supply, trade, and consumption | Annals of the New York Academy of Sciences | 2014 | 876 |
| 15 | Recruitment of human muscleblind proteins to (CUG)n expansions associated with myotonic dystrophy | EMBO Journal | 2000 | 802 |
| 16 | Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates | Nature Genetics | 2009 | 800 |
| 17 | Pseudoneglect: Effects of hemispace on a tactile line bisection task | Neuropsychologia | 1980 | 790 |
| 18 | Direct chemical bond of bioactive glass-ceramic materials to bone and muscle | Journal of Biomedical Materials Research Part B | 1973 | 785 |
| 19 | Deep EHR: A Survey of Recent Advances in Deep Learning Techniques for Electronic Health Record (EHR) Analysis | IEEE Journal of Biomedical and Health Informatics | 2018 | 782 |
| 20 | Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions | Lancet Infectious Diseases, The | 2014 | 745 |
| 21 | Gene Therapy Using Adeno-Associated Virus Vectors | Clinical Microbiology Reviews | 2008 | 734 |
| 22 | Enteric bacteria promote human and mouse norovirus infection of B cells | Science | 2014 | 689 |
| 23 | RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 681 |
| 24 | Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells | Nature Medicine | 2000 | 675 |
| 25 | The genomic landscape of hypodiploid acute lymphoblastic leukemia | Nature Genetics | 2013 | 588 |
| 26 | Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients | Journal of Experimental Medicine | 2012 | 572 |
| 27 | A Randomized Trial of Prasugrel Versus Clopidogrel in Patients With High Platelet Reactivity on Clopidogrel After Elective Percutaneous Coronary Intervention With Implantation of Drug-Eluting Stents | Journal of the American College of Cardiology | 2012 | 569 |
| 28 | Stages of oocyte development in the zebrafish,Brachydanio rerio | Journal of Morphology | 1993 | 566 |
| 29 | The family Parvoviridae | Archives of Virology | 2014 | 555 |
| 30 | Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation | Journal of Experimental Medicine | 2012 | 552 |
| 31 | US Assessment of HPV Types in Cancers: Implications for Current and 9-Valent HPV Vaccines | Journal of the National Cancer Institute | 2015 | 550 |
| 32 | Effects of a Physical Activity Intervention on Measures of Physical Performance: Results of the Lifestyle Interventions and Independence for Elders Pilot (LIFE-P) Study | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2006 | 533 |
| 33 | Viable SARS-CoV-2 in the air of a hospital room with COVID-19 patients | International Journal of Infectious Diseases | 2020 | 531 |
| 34 | Long-Term Survival and Late Deaths After Allogeneic Hematopoietic Cell Transplantation | Journal of Clinical Oncology | 2011 | 530 |
| 35 | Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors | Methods | 2002 | 514 |
| 36 | Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia | Blood | 2010 | 503 |
| 37 | Federated Learning for Healthcare Informatics | Journal of Healthcare Informatics Research | 2021 | 499 |
| 38 | Cognition and mood in Parkinson's disease in subthalamic nucleus versus globus pallidus interna deep brain stimulation: The COMPARE Trial | Annals of Neurology | 2009 | 489 |
| 39 | Adenosine and Adenosine Receptors in the Cardiovascular System: Biochemistry, Physiology, and Pharmacology | American Journal of Cardiology | 1997 | 485 |
| 40 | Polygenic control of susceptibility to murine systemic lupus erythematosus | Immunity | 1994 | 476 |
| 41 | The pharmacology of dichloroacetate | Metabolism: Clinical and Experimental | 1989 | 474 |
| 42 | Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats | Brain Research | 1994 | 456 |
| 43 | Two Types of Autoimmune Addisonʼs Disease Associated with Different Polyglandular Autoimmune (PGA) Syndromes | Medicine (United States) | 1981 | 454 |
| 44 | New insights into the role of mitochondria in aging: mitochondrial dynamics and more | Journal of Cell Science | 2010 | 448 |
| 45 | Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy | Human Molecular Genetics | 2006 | 445 |
| 46 | Effects of Alcohol Tax and Price Policies on Morbidity and Mortality: A Systematic Review | American Journal of Public Health | 2010 | 429 |
| 47 | Stem-Like Cells in Bone Sarcomas: Implications for Tumorigenesis | Neoplasia | 2005 | 426 |
| 48 | A method for the reconstruction of four-dimensional synchronized CT scans acquired during free breathing | Medical Physics | 2003 | 423 |
| 49 | Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450-2C19 (CYP2C19) Genotype and Clopidogrel Therapy | Clinical Pharmacology and Therapeutics | 2011 | 422 |
| 50 | THE ROLE OF THE RIGHT HEMISPHERE IN EMOTIONAL COMMUNICATION | Brain | 1991 | 420 |
