# | Title | Journal | Year | Citations |
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1 | Adult Bone Marrow Stromal Cells Differentiate into Neural Cells in Vitro | Experimental Neurology | 2000 | 1,369 |
2 | Isolation and Characterization of cDNAs Corresponding to an Additional Member of the Human Histone Deacetylase Gene Family | Journal of Biological Chemistry | 1997 | 396 |
3 | Adhesion to fibronectin via β1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR) | Oncogene | 2000 | 323 |
4 | The Pro-Apoptotic Proteins, Bid and Bax, Cause a Limited Permeabilization of the Mitochondrial Outer Membrane That Is Enhanced by Cytosol | Journal of Cell Biology | 1999 | 312 |
5 | The Geranylgeranyltransferase-I Inhibitor GGTI-298 Arrests Human Tumor Cells in G0/G1 and Induces p21WAF1/CIP1/SDI1 in a p53-independent Manner | Journal of Biological Chemistry | 1997 | 165 |
6 | Both Farnesylated and Geranylgeranylated RhoB Inhibit Malignant Transformation and Suppress Human Tumor Growth in Nude Mice | Journal of Biological Chemistry | 2000 | 165 |
7 | Inhibition of Protein Geranylgeranylation and RhoA/RhoA Kinase Pathway Induces Apoptosis in Human Endothelial Cells | Journal of Biological Chemistry | 2002 | 164 |
8 | Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I: combination therapy with the cytotoxic agents cisplatin, Taxol, and gemcitabine | Cancer Research | 1999 | 163 |
9 | Effect of thyroid hormone on hepatic cholesterol 7α hydroxylase, LDL receptor, HMG-CoA reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-I mRNA levels in hypophysectomized rats | Biochemical and Biophysical Research Communications | 1990 | 144 |
10 | Independent modulation of collagen fibrillogenesis by decorin and lumican | Cellular and Molecular Life Sciences | 2000 | 142 |
11 | Chromosome Missegregation and Trisomy 21 Mosaicism in Alzheimer's Disease | Neurobiology of Disease | 1999 | 140 |
12 | α-1-Antichymotrypsin Promotes β-Sheet Amyloid Plaque Deposition in a Transgenic Mouse Model of Alzheimer's Disease | Journal of Neuroscience | 2001 | 133 |
13 | Subunit Composition Determines E2F DNA-Binding Site Specificity | Molecular and Cellular Biology | 1997 | 126 |
14 | Feedback and Hormonal Regulation of Hepatic 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase: The Concept of Cholesterol Buffering Capacity | Proceedings of the Society for Experimental Biology and Medicine | 2000 | 125 |
15 | p21WAF1/CIP1 Is Upregulated by the Geranylgeranyltransferase I Inhibitor GGTI-298 through a Transforming Growth Factor β- and Sp1-Responsive Element: Involvement of the Small GTPase RhoA | Molecular and Cellular Biology | 1998 | 122 |
16 | Docking studies and model development of tea polyphenol proteasome inhibitors: Applications to rational drug design | Proteins: Structure, Function and Bioinformatics | 2003 | 111 |
17 | Inhibitors of Cholesterol Biosynthesis Increase Hepatic Low-Density Lipoprotein Receptor Protein Degradation | Archives of Biochemistry and Biophysics | 1996 | 103 |
18 | Chelatases: distort to select? | Trends in Biochemical Sciences | 2006 | 94 |
19 | 5-Aminolevulinate synthase and the first step of heme biosynthesis | Journal of Bioenergetics and Biomembranes | 1995 | 93 |
20 | Mechanism of Aminobisphosphonate Action: Characterization of Alendronate Inhibition of the Isoprenoid Pathway | Biochemical and Biophysical Research Communications | 1999 | 91 |
21 | Sequence and Regulation of a Gene Encoding a Human 89-Kilodalton Heat Shock Protein | Molecular and Cellular Biology | 1989 | 89 |
22 | Effects of l-Triiodothyronine and the Thyromimetic L-94901 on Serum Lipoprotein Levels and Hepatic Low-Density Lipoprotein Receptor, 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase, and Apo A-I Gene Expression | Biochemical Pharmacology | 1998 | 87 |
23 | Transcriptional Regulation of Rat Hepatic Low-Density Lipoprotein Receptor and Cholesterol 7α Hydroxylase by Thyroid Hormone | Archives of Biochemistry and Biophysics | 1995 | 82 |
24 | Argininosuccinate Synthase Expression Is Required to Maintain Nitric Oxide Production and Cell Viability in Aortic Endothelial Cells | Journal of Biological Chemistry | 2004 | 82 |
25 | Nitric oxide release from resting human platelets | Thrombosis Research | 1995 | 78 |
26 | Identification of E2F-3B, an alternative form of E2F-3 lacking a conserved N-terminal region | Oncogene | 2000 | 73 |
27 | Heme biosynthesis in mammalian systems: Evidence of a schiff base linkage between the pyridoxal 5′‐phosphate cofactor and a lysine residue in 5‐aminolevulinate synthase | Protein Science | 1993 | 72 |
28 | Insulin Regulates Alternative Splicing of Protein Kinase C βII through a Phosphatidylinositol 3-Kinase-dependent Pathway Involving the Nuclear Serine/Arginine-rich Splicing Factor, SRp40, in Skeletal Muscle Cells | Journal of Biological Chemistry | 2001 | 71 |
29 | Structure and function of ferrochelatase | Journal of Bioenergetics and Biomembranes | 1995 | 70 |
30 | Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation | Neurobiology of Aging | 2004 | 70 |
31 | Mammalian ferrochelatase, a new addition to the metalloenzyme family. | Journal of Biological Chemistry | 1994 | 70 |
32 | Tyrosine phosphorylation of focal adhesion kinase by PDGF is dependent on Ras in human hepatic stellate cells | Hepatology | 2000 | 67 |
33 | Feedback regulation of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase activity by dietary cholesterol is not due to altered mRNA levels | Journal of Biological Chemistry | 1991 | 67 |
34 | Retinoblastoma protein inhibits IFN-gamma induced apoptosis | Oncogene | 1996 | 67 |
35 | Rapid synthesis of isoprenoid diphosphates and their isolation in one step using either thin layer or flash chromatography | Journal of Chromatography A | 1993 | 64 |
36 | Porphyrin Interactions with Wild-type and Mutant Mouse Ferrochelatase | Biochemistry | 2000 | 64 |
37 | Signaling Events Required for Transforming Growth Factor-β Stimulation of Connective Tissue Growth Factor Expression by Cultured Human Lung Fibroblasts | Archives of Biochemistry and Biophysics | 2001 | 63 |
38 | Atorvastatin action involves diminished recovery of hepatic HMG-CoA reductase activity | Journal of Lipid Research | 1998 | 61 |
39 | Post-transcriptional Regulation of 3-Hydroxy-3-methylglutaryl-CoA Reductase mRNA in Rat Liver | Journal of Biological Chemistry | 1989 | 60 |
40 | Positive Regulatory Domain I Binding Factor 1 Silences Class II Transactivator Expression in Multiple Myeloma Cells | Journal of Biological Chemistry | 2001 | 58 |
41 | Mammalian ferrochelatase, a new addition to the metalloenzyme family | Journal of Biological Chemistry | 1994 | 58 |
42 | A Continuous Spectrophotometric Assay for 5-Aminolevulinate Synthase That Utilizes Substrate Cycling | Analytical Biochemistry | 1995 | 57 |
43 | Role of perlecan in skeletal development and diseases | Glycoconjugate Journal | 2002 | 57 |
44 | TGF-β1 Stimulation of Fibronectin Transcription in Cultured Human Lung Fibroblasts Requires Active Geranylgeranyl Transferase I, Phosphatidylcholine-Specific Phospholipase C, Protein Kinase C-δ, and p38, But Not erk1/erk2 | Archives of Biochemistry and Biophysics | 2000 | 56 |
45 | Effect of Squalene Synthase Inhibition on the Expression of Hepatic Cholesterol Biosynthetic-Enzymes, LDL Receptor, and Cholesterol 7α Hydroxylase | Archives of Biochemistry and Biophysics | 1994 | 55 |
46 | Pathways of aggrecan processing in joint tissues Implications for disease mechanism and monitoring | Acta Orthopaedica | 1995 | 55 |
47 | CEP1612, a dipeptidyl proteasome inhibitor, induces p21WAF1 and p27KIP1 expression and apoptosis and inhibits the growth of the human lung adenocarcinoma A-549 in nude mice | Cancer Research | 2001 | 55 |
48 | Partial restoration of the keratocyte phenotype to bovine keratocytes made fibroblastic by serum | Investigative Ophthalmology and Visual Science | 2002 | 55 |
49 | Insulin and glucagon modulate hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity by affecting immunoreactive protein levels. | Journal of Biological Chemistry | 1994 | 54 |
50 | Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Gene Expression by Sterols and Nonsterols in Rat Liver | Archives of Biochemistry and Biophysics | 1994 | 53 |