| # | Title | Journal | Year | Citations |
|---|
| 1 | Integrative analysis of 111 reference human epigenomes | Nature | 2015 | 5,653 |
| 2 | The fundamental role of epigenetic events in cancer | Nature Reviews Genetics | 2002 | 4,872 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 4 | Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease | Nature | 2011 | 4,238 |
| 5 | The Epigenomics of Cancer | Cell | 2007 | 4,039 |
| 6 | The Somatic Genomic Landscape of Glioblastoma | Cell | 2013 | 3,979 |
| 7 | Rules for Scoring Respiratory Events in Sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events | Journal of Clinical Sleep Medicine | 2012 | 3,887 |
| 8 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 9 | Antithrombotic Therapy for VTE Disease | Chest | 2012 | 3,745 |
| 10 | -Cell Deficit and Increased -Cell Apoptosis in Humans With Type 2 Diabetes | Diabetes | 2003 | 3,615 |
| 11 | Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach | Diabetes Care | 2012 | 3,077 |
| 12 | The ground state of embryonic stem cell self-renewal | Nature | 2008 | 3,057 |
| 13 | Epigenetics in human disease and prospects for epigenetic therapy | Nature | 2004 | 2,833 |
| 14 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,634 |
| 15 | A Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants | Science | 2007 | 2,534 |
| 16 | T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial | Lancet, The | 2015 | 2,476 |
| 17 | A decade of exploring the cancer epigenome — biological and translational implications | Nature Reviews Cancer | 2011 | 2,425 |
| 18 | Management of Hyperglycemia in Type 2 Diabetes, 2015: A Patient-Centered Approach: Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes | Diabetes Care | 2015 | 2,326 |
| 19 | Large-scale gene function analysis with the PANTHER classification system | Nature Protocols | 2013 | 2,276 |
| 20 | Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders | Nature Reviews Neuroscience | 2011 | 2,254 |
| 21 | American Cancer Society Guidelines for Breast Screening with MRI as an Adjunct to Mammography | Ca-A Cancer Journal for Clinicians | 2007 | 2,234 |
| 22 | Genome-wide association study identifies novel breast cancer susceptibility loci | Nature | 2007 | 2,165 |
| 23 | Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and Postpartum | Thyroid | 2011 | 2,014 |
| 24 | Prevention of VTE in Nonorthopedic Surgical Patients | Chest | 2012 | 1,819 |
| 25 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 26 | Hundreds of variants clustered in genomic loci and biological pathways affect human height | Nature | 2010 | 1,789 |
| 27 | Prevention of VTE in Nonsurgical Patients | Chest | 2012 | 1,780 |
| 28 | The Role of DNA Methylation in Mammalian Epigenetics | Science | 2001 | 1,746 |
| 29 | Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) | Diabetologia | 2012 | 1,718 |
| 30 | Absolute quantification of somatic DNA alterations in human cancer | Nature Biotechnology | 2012 | 1,710 |
| 31 | Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes | Nature Genetics | 2008 | 1,683 |
| 32 | Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines | Nature | 2010 | 1,651 |
| 33 | Newly identified loci that influence lipid concentrations and risk of coronary artery disease | Nature Genetics | 2008 | 1,488 |
| 34 | ACR Thyroid Imaging, Reporting and Data System (TI-RADS): White Paper of the ACR TI-RADS Committee | Journal of the American College of Radiology | 2017 | 1,473 |
| 35 | Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 1,471 |
| 36 | Blood-Brain Barrier Breakdown in the Aging Human Hippocampus | Neuron | 2015 | 1,436 |
| 37 | Risk of Death With Atypical Antipsychotic Drug Treatment for Dementia | JAMA - Journal of the American Medical Association | 2005 | 1,433 |
| 38 | Principles and challenges of genome-wide DNA methylation analysis | Nature Reviews Genetics | 2010 | 1,432 |
| 39 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 40 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 41 | Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria | Alzheimer's and Dementia | 2016 | 1,318 |
| 42 | Comprehensive analysis of CpG islands in human chromosomes 21 and 22 | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 1,294 |
| 43 | Nanoparticle biointerfacing by platelet membrane cloaking | Nature | 2015 | 1,270 |
| 44 | Guidelines on the Use of Therapeutic Apheresis in Clinical Practice – Evidence‐Based Approach from the Writing Committee of the American Society for Apheresis: The Eighth Special Issue | Journal of Clinical Apheresis | 2019 | 1,263 |
| 45 | Expanded encyclopaedias of DNA elements in the human and mouse genomes | Nature | 2020 | 1,252 |
| 46 | MicroRNAs and other non-coding RNAs as targets for anticancer drug development | Nature Reviews Drug Discovery | 2013 | 1,234 |
| 47 | Blood-Brain Barrier: From Physiology to Disease and Back | Physiological Reviews | 2019 | 1,232 |
| 48 | Carotid Artery Stenosis: Gray-Scale and Doppler US Diagnosis—Society of Radiologists in Ultrasound Consensus Conference | Radiology | 2003 | 1,225 |
| 49 | Clearance of Alzheimer’s amyloid-β1-40 peptide from brain by LDL receptor–related protein-1 at the blood-brain barrier | Journal of Clinical Investigation | 2000 | 1,213 |
| 50 | Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients | American Journal of Roentgenology | 2020 | 1,161 |
