| # | Title | Journal | Year | Citations |
|---|
| 1 | Ligand-Modified Cell Membrane Enables the Targeted Delivery of Drug Nanocrystals to Glioma | ACS Nano | 2019 | 238 |
| 2 | Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D1 receptors | Nature Communications | 2018 | 168 |
| 3 | VEGFR2 Functions As an H2S-Targeting Receptor Protein Kinase with Its Novel Cys1045–Cys1024 Disulfide Bond Serving As a Specific Molecular Switch for Hydrogen Sulfide Actions in Vascular Endothelial Cells | Antioxidants and Redox Signaling | 2013 | 145 |
| 4 | Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts | Journal of Clinical Investigation | 2021 | 144 |
| 5 | Role of Cystathionineγ-Lyase/Hydrogen Sulfide Pathway in Cardiovascular Disease: A Novel Therapeutic Strategy? | Antioxidants and Redox Signaling | 2012 | 122 |
| 6 | Selective Activation of Cholinergic Basal Forebrain Neurons Induces Immediate Sleep-wake Transitions | Current Biology | 2014 | 121 |
| 7 | Leonurine Protects Middle Cerebral Artery Occluded Rats Through Antioxidant Effect and Regulation of Mitochondrial Function | Stroke | 2010 | 120 |
| 8 | Hydrogen sulfide: third gaseous transmitter, but with great pharmacological potential | Acta Pharmacologica Sinica | 2007 | 117 |
| 9 | Single-cell transcriptome analysis reveals tumor immune microenvironment heterogenicity and granulocytes enrichment in colorectal cancer liver metastases | Cancer Letters | 2020 | 114 |
| 10 | Hydrogen Sulfide Attenuated Tumor Necrosis Factor-α-Induced Inflammatory Signaling and Dysfunction in Vascular Endothelial Cells | PLoS ONE | 2011 | 109 |
| 11 | The Cardioprotective Effects of Hydrogen Sulfide in Heart Diseases: From Molecular Mechanisms to Therapeutic Potential | Oxidative Medicine and Cellular Longevity | 2015 | 107 |
| 12 | Basal Forebrain Cholinergic Neurons Primarily Contribute to Inhibition of Electroencephalogram Delta Activity, Rather Than Inducing Behavioral Wakefulness in Mice | Neuropsychopharmacology | 2016 | 104 |
| 13 | Protective Effects of Cysteine Analogues on Acute Myocardial Ischemia: Novel Modulators of Endogenous H2S Production | Antioxidants and Redox Signaling | 2010 | 102 |
| 14 | S-Propargyl-cysteine, a novel hydrogen sulfide-modulated agent, attenuates lipopolysaccharide-induced spatial learning and memory impairment: Involvement of TNF signaling and NF-κB pathway in rats | Brain, Behavior, and Immunity | 2011 | 98 |
| 15 | miRNA-30 Family Inhibition Protects Against Cardiac Ischemic Injury by Regulating Cystathionine-γ-Lyase Expression | Antioxidants and Redox Signaling | 2015 | 96 |
| 16 | Ursodeoxycholic acid and 4-phenylbutyrate prevent endoplasmic reticulum stress-induced podocyte apoptosis in diabetic nephropathy | Laboratory Investigation | 2016 | 95 |
| 17 | A Novel Potent Anticancer Compound Optimized from a Natural Oridonin Scaffold Induces Apoptosis and Cell Cycle Arrest through the Mitochondrial Pathway | Journal of Medicinal Chemistry | 2017 | 93 |
| 18 | H2S Donor, S-Propargyl-Cysteine, Increases CSE in SGC-7901 and Cancer-Induced Mice: Evidence for a Novel Anti-Cancer Effect of Endogenous H2S? | PLoS ONE | 2011 | 89 |
| 19 | S-propargyl-cysteine Protects Both Adult Rat Hearts and Neonatal Cardiomyocytes From Ischemia/Hypoxia Injury: The Contribution of the Hydrogen Sulfide-Mediated Pathway | Journal of Cardiovascular Pharmacology | 2009 | 88 |
| 20 | The Neurobiological Mechanisms and Treatments of REM Sleep Disturbances in Depression | Current Neuropharmacology | 2015 | 87 |
| 21 | Hydrogen sulfide attenuates cardiac dysfunction in a rat model of heart failure: a mechanism through cardiac mitochondrial protection | Bioscience Reports | 2011 | 86 |
| 22 | Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus | ELife | 2017 | 86 |
| 23 | Beneficial effect of tripterine on systemic lupus erythematosus induced by active chromatin in BALB/c mice | European Journal of Pharmacology | 2005 | 82 |
| 24 | Macrophage-based nanotherapeutic strategies in ulcerative colitis | Journal of Controlled Release | 2020 | 82 |
| 25 | Red light at intensities above 10 lx alters sleep–wake behavior in mice | Light: Science and Applications | 2017 | 81 |
| 26 | Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand | Nature Communications | 2017 | 81 |
| 27 | Modulating the gut microbiota and inflammation is involved in the effect of Bupleurum polysaccharides against diabetic nephropathy in mice | International Journal of Biological Macromolecules | 2019 | 80 |
| 28 | Flavonoids from Houttuynia cordata attenuate H1N1-induced acute lung injury in mice via inhibition of influenza virus and Toll-like receptor signalling | Phytomedicine | 2020 | 80 |
| 29 | New method for quantification of gasotransmitter hydrogen sulfide in biological matrices by LC-MS/MS | Scientific Reports | 2017 | 79 |
| 30 | Astragaloside IV protects against podocyte injury via SERCA2-dependent ER stress reduction and AMPKα-regulated autophagy induction in streptozotocin-induced diabetic nephropathy | Scientific Reports | 2017 | 79 |
| 31 | Hydrogen sulfide protects against apoptosis under oxidative stress through SIRT1 pathway in H9c2 cardiomyocytes | Nitric Oxide - Biology and Chemistry | 2015 | 78 |
| 32 | Houttuynia cordata polysaccharides ameliorate pneumonia severity and intestinal injury in mice with influenza virus infection | Journal of Ethnopharmacology | 2018 | 77 |
| 33 | A New Hope for Neurodegeneration: Possible Role of Hydrogen Sulfide | Journal of Alzheimer's Disease | 2011 | 76 |
| 34 | Leonurine (SCM-198) attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4 | Free Radical Biology and Medicine | 2013 | 76 |
| 35 | S-Propargyl-Cysteine, a Novel Water-Soluble Modulator of Endogenous Hydrogen Sulfide, Promotes Angiogenesis Through Activation of Signal Transducer and Activator of Transcription 3 | Antioxidants and Redox Signaling | 2014 | 76 |
| 36 | Bupleurum chinense DC polysaccharides attenuates lipopolysaccharide-induced acute lung injury in mice | Phytomedicine | 2012 | 75 |
| 37 | Interplay of Oxidative Stress and Autophagy in PAMAM Dendrimers-Induced Neuronal Cell Death | Theranostics | 2015 | 75 |
| 38 | The Role of Hydrogen Sulfide on Cardiovascular Homeostasis: An Overview with Update on Immunomodulation | Frontiers in Pharmacology | 2017 | 75 |
| 39 | Curcumin Inhibits Transforming Growth Factor-β1-Induced EMT via PPARγ Pathway, Not Smad Pathway in Renal Tubular Epithelial Cells | PLoS ONE | 2013 | 74 |
| 40 | Design of Y-shaped targeting material for liposome-based multifunctional glioblastoma-targeted drug delivery | Journal of Controlled Release | 2017 | 74 |
| 41 | In vivo effect of quantified flavonoids-enriched extract of Scutellaria baicalensis root on acute lung injury induced by influenza A virus | Phytomedicine | 2019 | 74 |
| 42 | Hypoxia blocks ferroptosis of hepatocellular carcinoma via suppression of METTL14 triggered YTHDF2‐dependent silencing of SLC7A11 | Journal of Cellular and Molecular Medicine | 2021 | 73 |
| 43 | Neuroprotective Effects of Leonurine on Ischemia/Reperfusion-Induced Mitochondrial Dysfunctions in Rat Cerebral Cortex | Biological and Pharmaceutical Bulletin | 2010 | 72 |
| 44 | Inhibition of NADPH oxidase 4-related signaling by sodium hydrosulfide attenuates myocardial fibrotic response | International Journal of Cardiology | 2013 | 72 |
| 45 | Liposome-Based Systemic Glioma-Targeted Drug Delivery Enabled by All-d Peptides | ACS Applied Materials & Interfaces | 2016 | 72 |
| 46 | HDAC4 regulates vascular inflammation via activation of autophagy | Cardiovascular Research | 2018 | 72 |
| 47 | Hypoxia-Inducible Factor-1.ALPHA. Is Involved in the Pro-angiogenic Effect of Hydrogen Sulfide under Hypoxic Stress | Biological and Pharmaceutical Bulletin | 2010 | 71 |
| 48 | S-Propargyl-cysteine (SPRC) attenuated lipopolysaccharide-induced inflammatory response in H9c2 cells involved in a hydrogen sulfide-dependent mechanism | Amino Acids | 2011 | 71 |
| 49 | Hydrogen Sulfide as an Endogenous Modulator in Mitochondria and Mitochondria Dysfunction | Oxidative Medicine and Cellular Longevity | 2012 | 71 |
| 50 | Hydrogen Sulfide Attenuates Inflammatory Hepcidin by Reducing IL-6 Secretion and Promoting SIRT1-Mediated STAT3 Deacetylation | Antioxidants and Redox Signaling | 2016 | 71 |
