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#TitleJournalYearCitations
1Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent DioxygenasesCancer Cell20112,340
2Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancerInternational Journal of Cancer2010843
3PD-L1 Immunohistochemistry Comparability Study in Real-Life Clinical Samples: Results of Blueprint Phase 2 ProjectJournal of Thoracic Oncology2018589
4A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastomaNature Communications2018519
5Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylationOncogene2013499
6Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor GrowthMolecular Cell2011479
7Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma (2019 Edition)Liver Cancer2020427
8Guidelines for Diagnosis and Treatment of Primary Liver Cancer in China (2017 Edition)Liver Cancer2018426
9The Protective Role of Nrf2 in Streptozotocin-Induced Diabetic NephropathyDiabetes2010383
10Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxiaNature Communications2016306
11Over‐expressed microRNA‐27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activationFEBS Letters2009275
12LncRNA PVT1 promotes angiogenesis via activating the STAT3/VEGFA axis in gastric cancerOncogene2018275
13Lysine-5 Acetylation Negatively Regulates Lactate Dehydrogenase A and Is Decreased in Pancreatic CancerCancer Cell2013257
14MicroRNA 23b Regulates Autophagy Associated With Radioresistance of Pancreatic Cancer CellsGastroenterology2013223
15Tumour-associated macrophages-derived CXCL8 determines immune evasion through autonomous PD-L1 expression in gastric cancerGut2019219
16Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivinNature Cell Biology2012218
17Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung CancerJournal of Thoracic Oncology2019212
18CSH guidelines for the diagnosis and treatment of drug-induced liver injuryHepatology International2017206
19AKI and Collapsing Glomerulopathy Associated with COVID-19 and APOL 1 High-Risk GenotypeJournal of the American Society of Nephrology: JASN2020204
20Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1Oncogene2014198
21Plasma miR-601 and miR-760 Are Novel Biomarkers for the Early Detection of Colorectal CancerPLoS ONE2012191
22Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-κB-mediated inflammatory responseKidney International2014190
23miR‐340 inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c‐MetCancer2011180
24Adult IDH wild-type lower-grade gliomas should be further stratifiedNeuro-Oncology2017177
25Brain-targeted drug delivery by manipulating protein corona functionsNature Communications2019174
26Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver CancerCancer Cell2017172
27A microRNA 221– and 222–Mediated Feedback Loop Maintains Constitutive Activation of NFκB and STAT3 in Colorectal Cancer CellsGastroenterology2014167
28Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populationsNature Genetics2012164
29The serum miR‐21 level serves as a predictor for the chemosensitivity of advanced pancreatic cancer, and miR‐21 expression confers chemoresistance by targeting FasLMolecular Oncology2013161
30Enhanced Tumor Synergistic Therapy by Injectable Magnetic Hydrogel Mediated Generation of Hyperthermia and Highly Toxic Reactive Oxygen SpeciesACS Nano2019161
31Involvement of NF-κB/miR-448 regulatory feedback loop in chemotherapy-induced epithelial–mesenchymal transition of breast cancer cellsCell Death and Differentiation2011159
32Classification and Differential Diagnosis of Diabetic NephropathyJournal of Diabetes Research2017159
33EGFR Mutation Testing Practices within the Asia Pacific Region: Results of a Multicenter Diagnostic SurveyJournal of Thoracic Oncology2015156
34miR-124 is frequently down-regulated in medulloblastoma and is a negative regulator of SLC16A1Human Pathology2009155
35Invasive neuroendocrine carcinoma of the breastCancer2010151
36Licochalcone A inhibits growth of gastric cancer cells by arresting cell cycle progression and inducing apoptosisCancer Letters2011146
37Schwannoma of the gastrointestinal tract: a clinicopathological, immunohistochemical and ultrastructural study of 33 casesHistopathology2006144
38Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacyJournal of Clinical Investigation2019143
39Berberine reduces methylation of the MTTP promoter and alleviates fatty liver induced by a high-fat diet in ratsJournal of Lipid Research2010142
40Long noncoding RNA CCAL transferred from fibroblasts by exosomes promotes chemoresistance of colorectal cancer cellsInternational Journal of Cancer2020142
41Comparison of patterns and prognosis among distant metastatic breast cancer patients by age groups: a SEER population-based analysisScientific Reports2017139
42A plasma microRNA panel for early detection of colorectal cancerInternational Journal of Cancer2015138
43Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinomaNature Communications2014137
44The IL-8/CXCR1 axis is associated with cancer stem cell-like properties and correlates with clinical prognosis in human pancreatic cancer casesScientific Reports2014135
45VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinomaScience2018134
46MicroRNA-95 Promotes Cell Proliferation and Targets Sorting Nexin 1 in Human Colorectal CarcinomaCancer Research2011129
47A Pharmacogenomic Landscape in Human Liver CancersCancer Cell2019127
48CD133: A cancer stem cells marker, is used in colorectal cancersWorld Journal of Gastroenterology2013125
49Cutaneous Rosai-Dorfman DiseaseAmerican Journal of Surgical Pathology2007121
50ErbB2 overexpression correlates with increased expression of vascular endothelial growth factors A, C, and D in human breast carcinomaCancer2002118