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exaly
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Department of Biochemistry and Molecular Genetics
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top-articles
Department of Biochemistry and Molecular Genetics
55
(top 2%)
papers
3.2K
(top 1%)
citations
27
(top 1%)
h
-index
54
(top 1%)
g
-index
56
all documents
3.4K
doc citations
994
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression
Cancer Cell
2012
504
2
Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo
Journal of Experimental Medicine
2013
278
3
Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase
Proceedings of the National Academy of Sciences of the United States of America
1997
258
4
Long-term correction of inhibitor-prone hemophilia B dogs treated with liver-directed AAV2-mediated factor IX gene therapy
Blood
2009
247
5
Disaccharide uptake and priming in animal cells: inhibition of sialyl Lewis X by acetylated Gal beta 1-->4GlcNAc beta-O-naphthalenemethanol.
Proceedings of the National Academy of Sciences of the United States of America
1995
198
6
The Wnt/β-Catenin→Pitx2 Pathway Controls the Turnover of Pitx2 and Other Unstable mRNAs
Molecular Cell
2003
156
7
Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis
Blood
2012
137
8
Inactivating Mutation of the Mouse Tissue Inhibitor of Metalloproteinases-2(Timp-2) Gene Alters ProMMP-2 Activation
Journal of Biological Chemistry
2000
123
9
Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation
Proceedings of the National Academy of Sciences of the United States of America
2000
116
10
Biosynthesis of heparan sulfate on beta-D-xylosides depends on aglycone structure
Journal of Biological Chemistry
1994
113
11
Regulation of Histone H2A and H2B Deubiquitination and Xenopus Development by USP12 and USP46
Journal of Biological Chemistry
2011
94
12
Clustered O-Glycans of IgA1
Molecular and Cellular Proteomics
2010
86
13
Structural Analysis of Apolipoprotein A-I: Effects of Amino- and Carboxy-Terminal Deletions on the Lipid-Free Structure†
Biochemistry
1998
85
14
The Paf1 complex is required for efficient transcription elongation by RNA polymerase I
Proceedings of the National Academy of Sciences of the United States of America
2009
82
15
Diamidine Compounds for Selective Inhibition of Protein Arginine Methyltransferase 1
Journal of Medicinal Chemistry
2014
77
16
Transcription-induced barriers to supercoil diffusion in the Salmonella typhimurium chromosome
Proceedings of the National Academy of Sciences of the United States of America
2004
69
17
A trypanosome oligopeptidase as a target for the trypanocidal agents pentamidine, diminazene and suramin
FEBS Letters
1998
63
18
Kinetic Analysis of Human Enzyme RDH10 Defines the Characteristics of a Physiologically Relevant Retinol Dehydrogenase
Journal of Biological Chemistry
2008
59
19
A Trypanosome Mitochondrial RNA Polymerase Is Required for Transcription and Replication
Journal of Biological Chemistry
2002
53
20
Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich’s Ataxia Cells
Cell Reports
2016
51
21
DNA topology of highly transcribed operons in
Salmonella enterica
serovar Typhimurium
Molecular Microbiology
2010
46
22
Ca2+-induced Conformational Transition in the Inhibitory and Regulatory Regions of Cardiac Troponin I
Journal of Biological Chemistry
2003
43
23
Identification of haptoglobin as a natural inhibitor of trypanocidal activity in human serum.
Proceedings of the National Academy of Sciences of the United States of America
1995
41
24
Monoclonal Antibodies Directed against the Amino-Terminal Domain of Human TBP Cross-React with TBP from Other Species
Hybridoma
1996
35
25
Human Papillomavirus and Cancer Prevention: Gaps in Knowledge and Prospects for Research, Policy, and Advocacy
Vaccine
2012
35
26
The DNA Cleavage Reaction of DNA Gyrase
Journal of Biological Chemistry
1997
33
27
The role of ALDH2 and ADH1B polymorphism in alcohol consumption and stroke in Han Chinese
Human Genomics
2011
29
28
Förster Resonance Energy Transfer Structural Kinetic Studies of Cardiac Thin Filament Deactivation
Journal of Biological Chemistry
2009
25
29
Under DNA stress, gyrase makes the sign of the cross
Nature Structural and Molecular Biology
2007
22
30
Kinetics of Conformational Transitions in Cardiac Troponin Induced by Ca2+ Dissociation Determined by Förster Resonance Energy Transfer
Journal of Biological Chemistry
2003
20
31
Progression of behavioural despair in R6/2 and Hdh knock-in mouse models recapitulates depression in Huntington's disease
Behavioural Brain Research
2015
19
32
Analysis of the 5′ end of the mouse Elavl1 (mHuA) gene reveals a transcriptional regulatory element and evidence for conserved genomic organization
Gene
2000
17
33
Recognition of the Inner Lipoyl-Bearing Domain of Dihydrolipoyl Transacetylase and of the Blood Glucose-Lowering Compound AZD7545 by Pyruvate Dehydrogenase Kinase 2
Biochemistry
2007
17
34
Loss of
RUNX
1/
AML
1 arginine‐methylation impairs peripheral T cell homeostasis
British Journal of Haematology
2015
17
35
Evolutionary origins of retinoid active short-chain dehydrogenases/reductases of SDR16C family
Chemico-Biological Interactions
2015
17
36
Efficient electroporation of neuronal cells using synthetic oligonucleotides: identifying duplex RNA and antisense oligonucleotide activators of human frataxin expression
Rna
2019
17
37
Characterization of essential domains in HSD17B13 for cellular localization and enzymatic activity
Journal of Lipid Research
2020
17
38
Cloning, expression, purification, crystallization and initial crystallographic analysis of transcription elongation factors GreB fromEscherichia coliand Gfh1 fromThermus thermophilus
Acta Crystallographica Section F: Structural Biology Communications
2006
15
39
Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands
Journal of Biological Chemistry
2019
15
40
The Carboxy-Terminal Tail of Pyruvate Dehydrogenase Kinase 2 Is Required for the Kinase Activity
Biochemistry
2005
13
41
Tracking RNA Polymerase, One Step at a Time
Cell
2005
13
42
Erythropoiesis in the Absence of Adult Hemoglobin
Molecular and Cellular Biology
2013
12
43
Progress towards drug discovery for Friedreich’s Ataxia: Identifying synthetic oligonucleotides that more potently activate expression of human frataxin protein
Bioorganic and Medicinal Chemistry
2020
12
44
Characterization of the pgf operon involved in the posttranslational modification of Streptococcus mutans surface proteins
Scientific Reports
2018
11
45
Relative stabilities of wild-type and mutant glial fibrillary acidic protein in patients with Alexander disease
Journal of Biological Chemistry
2019
8
46
Inhibition of Neurogenesis by Zika Virus Infection
CNS and Neurological Disorders - Drug Targets
2018
7
47
Arginine Methylation Of RBM15 By PRMT1 Controls Alternative Splicing Of Genes Involved In Megakaryocyte Differentiation
Blood
2013
7
48
Myocardial strain in sub-acute peri-infarct myocardium
International Journal of Cardiovascular Imaging
2009
6
49
Nuclear Magnetic Resonance Studies on Complementary Peptides
ImmunoMethods
1994
5
50
Rapid method for the fractionation of nuclear proteins and their complexes by batch elution from hydroxyapatite
Journal of Chromatography A
1993
4
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