| # | Title | Journal | Year | Citations |
|---|
| 1 | A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease | Cell | 2017 | 3,282 |
| 2 | Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19 | Nature Medicine | 2020 | 2,083 |
| 3 | Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment | Cell | 2014 | 1,705 |
| 4 | Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types | Science | 2014 | 1,563 |
| 5 | The Human Cell Atlas | ELife | 2017 | 1,547 |
| 6 | Artificial sweeteners induce glucose intolerance by altering the gut microbiota | Nature | 2014 | 1,529 |
| 7 | The microbiome and innate immunity | Nature | 2016 | 1,502 |
| 8 | Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms | Nature Reviews Cancer | 2013 | 1,497 |
| 9 | Control of microglial neurotoxicity by the fractalkine receptor | Nature Neuroscience | 2006 | 1,334 |
| 10 | Immune cell migration in inflammation: present and future therapeutic targets | Nature Immunology | 2005 | 1,145 |
| 11 | Dysbiosis and the immune system | Nature Reviews Immunology | 2017 | 1,102 |
| 12 | Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine | Science | 2017 | 1,059 |
| 13 | Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor | Nature Medicine | 2016 | 987 |
| 14 | Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis | Cell | 2014 | 984 |
| 15 | Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses | Cell | 2017 | 937 |
| 16 | A Clonogenic Bone Marrow Progenitor Specific for Macrophages and Dendritic Cells | Science | 2006 | 924 |
| 17 | Microglia development follows a stepwise program to regulate brain homeostasis | Science | 2016 | 911 |
| 18 | How do stem cells find their way home? | Blood | 2005 | 901 |
| 19 | Leukocyte Migration into Inflamed Tissues | Immunity | 2014 | 882 |
| 20 | Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors | Cell | 2015 | 875 |
| 21 | Single-cell spatial reconstruction reveals global division of labour in the mammalian liver | Nature | 2017 | 809 |
| 22 | The aging of hematopoietic stem cells | Nature Medicine | 1996 | 790 |
| 23 | Microglia Biology: One Century of Evolving Concepts | Cell | 2019 | 772 |
| 24 | Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration | Cell | 2018 | 765 |
| 25 | Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma | Cell | 2019 | 760 |
| 26 | A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration | Nature Methods | 2005 | 744 |
| 27 | Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling | Cell | 2015 | 728 |
| 28 | Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner | Cell | 2019 | 718 |
| 29 | Chromatin state dynamics during blood formation | Science | 2014 | 699 |
| 30 | Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells | Nature Medicine | 2006 | 697 |
| 31 | Macrophages: Development and Tissue Specialization | Annual Review of Immunology | 2015 | 687 |
| 32 | Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19 | Cell | 2020 | 663 |
| 33 | NASH limits anti-tumour surveillance in immunotherapy-treated HCC | Nature | 2021 | 649 |
| 34 | Development and Function of Dendritic Cell Subsets | Immunity | 2014 | 637 |
| 35 | Prediction of acute myeloid leukaemia risk in healthy individuals | Nature | 2018 | 617 |
| 36 | Ectopic colonization of oral bacteria in the intestine drives T H 1 cell induction and inflammation | Science | 2017 | 612 |
| 37 | Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq | Cell | 2016 | 604 |
| 38 | Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations | Cell | 2016 | 591 |
| 39 | Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection | Science | 2018 | 582 |
| 40 | In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma | Journal of Experimental Medicine | 2005 | 573 |
| 41 | Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner | Cell | 2018 | 563 |
| 42 | HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver | Journal of Clinical Investigation | 2003 | 526 |
| 43 | Wishbone identifies bifurcating developmental trajectories from single-cell data | Nature Biotechnology | 2016 | 523 |
| 44 | Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System | Immunity | 2015 | 506 |
| 45 | Guidelines for the use of flow cytometry and cell sorting in immunological studies* | European Journal of Immunology | 2017 | 505 |
| 46 | β-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial | Lancet, The | 2001 | 501 |
| 47 | The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome | Cell | 2016 | 465 |
| 48 | Aging-induced type I interferon response at the choroid plexus negatively affects brain function | Science | 2014 | 463 |
| 49 | Our Gut Microbiome: The Evolving Inner Self | Cell | 2017 | 462 |
| 50 | Macrophage-Restricted Interleukin-10 Receptor Deficiency, but Not IL-10 Deficiency, Causes Severe Spontaneous Colitis | Immunity | 2014 | 460 |
