| # | Title | Journal | Year | Citations |
|---|
| 1 | Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck | New England Journal of Medicine | 2006 | 4,705 |
| 2 | Microarray data analysis: from disarray to consolidation and consensus | Nature Reviews Genetics | 2006 | 1,186 |
| 3 | Human Immunodeficiency Virus Type 1 env Clones from Acute and Early Subtype B Infections for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies | Journal of Virology | 2005 | 1,025 |
| 4 | Continuous renal replacement therapy: A worldwide practice survey | Intensive Care Medicine | 2007 | 1,020 |
| 5 | Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75 Years | JAMA - Journal of the American Medical Association | 2016 | 991 |
| 6 | High Titers of Cytopathic Virus in Plasma of Patients with Symptomatic Primary HIV-1 Infection | New England Journal of Medicine | 1991 | 685 |
| 7 | Superoxide and peroxynitrite in atherosclerosis. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 659 |
| 8 | Comparison of Amphotericin B with Fluconazole in the Treatment of Acute AIDS-Associated Cryptococcal Meningitis | New England Journal of Medicine | 1992 | 643 |
| 9 | Left Ventricular Volumes and Ejection Fraction by Echocardiography | Circulation | 1971 | 640 |
| 10 | Rapid Loss of Vertebral Mineral Density after Renal Transplantation | New England Journal of Medicine | 1991 | 622 |
| 11 | MYH9 is associated with nondiabetic end-stage renal disease in African Americans | Nature Genetics | 2008 | 587 |
| 12 | Oral Azole Drugs as Systemic Antifungal Therapy | New England Journal of Medicine | 1994 | 565 |
| 13 | Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance | Nature | 2008 | 508 |
| 14 | Parental Monitoring: Association With Adolescents' Risk Behaviors | Pediatrics | 2001 | 495 |
| 15 | Human infection by genetically diverse SIVSM-related HIV-2 in West Africa | Nature | 1992 | 486 |
| 16 | COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup | Nature Reviews Nephrology | 2020 | 466 |
| 17 | Long-term follow-up and prognostic factor analysis in advanced ovarian carcinoma: the Gynecologic Oncology Group experience. | Journal of Clinical Oncology | 1991 | 437 |
| 18 | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1 | Journal of Lipid Research | 2000 | 423 |
| 19 | Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes | Journal of Virology | 1991 | 400 |
| 20 | Epidemiology and Natural History of Urinary Incontinence | International Urogynecology Journal | 2000 | 390 |
| 21 | Phenotypic properties of transmitted founder HIV-1 | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 379 |
| 22 | Randomized controlled study of extracorporeal albumin dialysis for hepatic encephalopathy in advanced cirrhosis | Hepatology | 2007 | 367 |
| 23 | Asthma and gastroesophageal reflux: Acid suppressive therapy improves asthma outcome | American Journal of Medicine | 1996 | 366 |
| 24 | Requisite Role for the Dectin-1 β-Glucan Receptor in Pulmonary Defense against Aspergillus fumigatus | Journal of Immunology | 2009 | 365 |
| 25 | Selective radiofrequency ablation of the slow pathway for the treatment of atrioventricular nodal reentrant tachycardia. Evidence for involvement of perinodal myocardium within the reentrant circuit. | Circulation | 1992 | 355 |
| 26 | Novel Single Nucleotide Polymorphisms in the Distal IL-10 Promoter Affect IL-10 Production and Enhance the Risk of Systemic Lupus Erythematosus | Journal of Immunology | 2001 | 353 |
| 27 | HMGB1 Develops Enhanced Proinflammatory Activity by Binding to Cytokines | Journal of Immunology | 2008 | 353 |
| 28 | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3 | Journal of Lipid Research | 2000 | 353 |
| 29 | Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies | Infection and Immunity | 1991 | 349 |
| 30 | Bacterial Vaginosis Assessed by Gram Stain and Diminished Colonization Resistance to Incident Gonococcal, Chlamydial, and Trichomonal Genital Infection | Journal of Infectious Diseases | 2010 | 344 |
| 31 | Genetic and Neutralization Properties of Subtype C Human Immunodeficiency Virus Type 1 Molecular env Clones from Acute and Early Heterosexually Acquired Infections in Southern Africa | Journal of Virology | 2006 | 334 |
| 32 | Magnitude of Functional CD8 + T-Cell Responses to the Gag Protein of Human Immunodeficiency Virus Type 1 Correlates Inversely with Viral Load in Plasma | Journal of Virology | 2002 | 331 |
| 33 | Prognosis in systemic lupus erythematosus | Arthritis and Rheumatism | 1990 | 323 |
| 34 | Selective hypersensitivity to granulocyte-macrophage colony-stimulating factor by juvenile chronic myeloid leukemia hematopoietic progenitors | Blood | 1991 | 318 |
| 35 | Transfection of the CD20 cell surface molecule into ectopic cell types generates a Ca2+ conductance found constitutively in B lymphocytes. | Journal of Cell Biology | 1993 | 315 |
| 36 | Intestinal Macrophages Lack CD14 and CD89 and Consequently Are Down-Regulated for LPS- and IgA-Mediated Activities | Journal of Immunology | 2001 | 298 |
| 37 | Immunologic abnormalities in pathogen-free cats experimentally infected with feline immunodeficiency virus | Journal of Virology | 1990 | 296 |
| 38 | Epidemiology of Knee and Hip Arthroplasty: A Systematic Review§ | The Open Orthopaedics Journal | 2011 | 280 |
| 39 | The Amphipathic α Helix: A Multifunctional Structural Motif in Plasma Apolipoproteins | Advances in Protein Chemistry | 1994 | 276 |
| 40 | Factors associated with resilience to and recovery from burnout: a prospective, multi-institutional study of US medical students | Medical Education | 2010 | 268 |
| 41 | Preferential utilization of conserved immunoglobulin heavy chain variable gene segments during human fetal life. | Proceedings of the National Academy of Sciences of the United States of America | 1990 | 260 |
| 42 | Covalently Linked Au Nanoparticles to a Viral Vector: Potential for Combined Photothermal and Gene Cancer Therapy | Nano Letters | 2006 | 250 |
| 43 | The right ventricle: anatomy, physiology, and clinical importance | Current Problems in Cardiology | 1991 | 244 |
| 44 | Novel Therapies Based on Mechanisms of HIV-1 Cell Entry | New England Journal of Medicine | 2003 | 243 |
| 45 | Cohort profile: the Centers for AIDS Research Network of Integrated Clinical Systems | International Journal of Epidemiology | 2008 | 242 |
| 46 | Pressure Ulcers among the Elderly | New England Journal of Medicine | 1989 | 240 |
| 47 | Clinical risk factors for portopulmonary hypertension | Hepatology | 2008 | 239 |
| 48 | Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: two cellular mechanisms explain joint destruction? | Annals of the Rheumatic Diseases | 1993 | 236 |
| 49 | Impact of Hepatopulmonary Syndrome on Quality of Life and Survival in Liver Transplant Candidates | Gastroenterology | 2008 | 236 |
| 50 | Cellular distribution, regulation, and biochemical nature of an Fc alpha receptor in humans. | Journal of Experimental Medicine | 1990 | 231 |
