# | Title | Journal | Year | Citations |
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1 | Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine | Neuropharmacology | 1986 | 1,247 |
2 | Airway Smooth Muscle Cell Proliferation Is Increased in Asthma | American Journal of Respiratory and Critical Care Medicine | 2001 | 475 |
3 | How opioids inhibit GABA-mediated neurotransmission | Nature | 1997 | 468 |
4 | THE 'ABC' OF GABA RECEPTORS: A BRIEF REVIEW | Clinical and Experimental Pharmacology and Physiology | 1999 | 347 |
5 | GABA-Activated Ligand Gated Ion Channels: Medicinal Chemistry and Molecular Biology | Journal of Medicinal Chemistry | 2000 | 326 |
6 | Parkinson's disease, pesticides, and glutathione transferase polymorphisms | Lancet, The | 1998 | 303 |
7 | GABAA receptor pharmacology | Lancet, The | 1996 | 292 |
8 | Adolescent Rats Find Repeated Δ9-THC Less Aversive Than Adult Rats but Display Greater Residual Cognitive Deficits and Changes in Hippocampal Protein Expression Following Exposure | Neuropsychopharmacology | 2008 | 271 |
9 | Interaction between glucocorticoids and β 2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling | Lancet, The | 2002 | 261 |
10 | Dysfunctional Interaction of C/EBPα and the Glucocorticoid Receptor in Asthmatic Bronchial Smooth-Muscle Cells | New England Journal of Medicine | 2004 | 254 |
11 | Footshock induced analgesia in mice: Its reversal by naloxone and cross tolerance with morphine | Life Sciences | 1977 | 240 |
12 | GABAA Receptor Channel Pharmacology | Current Pharmaceutical Design | 2005 | 240 |
13 | DPA-714, a New Translocator Protein–Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization | Journal of Nuclear Medicine | 2008 | 237 |
14 | Increase by the ORL1 receptor (opioid receptor‐like1) ligand, nociceptin, of inwardly rectifying K conductance in dorsal raphe nucleus neurones | British Journal of Pharmacology | 1996 | 215 |
15 | Central nervous system depressant action of flavonoid glycosides | European Journal of Pharmacology | 2006 | 215 |
16 | 2-Hydroxy-saclofen: an improved antagonist at central and peripheral GABAB receptors | Neuroscience Letters | 1988 | 212 |
17 | OPIOID RECEPTOR SIGNALLING MECHANISMS | Clinical and Experimental Pharmacology and Physiology | 1999 | 207 |
18 | Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro | British Journal of Pharmacology | 1996 | 206 |
19 | Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy | Lancet Oncology, The | 2003 | 205 |
20 | Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal grey in vitro. | Journal of Physiology | 1997 | 203 |
21 | Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response | British Journal of Cancer | 2002 | 198 |
22 | Discovery and characterization of a family of insecticidal neurotoxins with a rare vicinal disulfide bridge | Nature Structural Biology | 2000 | 194 |
23 | Flavonoid modulation of GABAA receptors | British Journal of Pharmacology | 2011 | 192 |
24 | Extracellular matrix proteins modulate asthmatic airway smooth muscle cell proliferation via an autocrine mechanism | Journal of Allergy and Clinical Immunology | 2004 | 191 |
25 | Actions of cannabinoids on membrane properties and synaptic transmission in rat periaqueductal gray neurons in vitro | Molecular Pharmacology | 2000 | 188 |
26 | Anatomy and electrophysiology of fast central synapses lead to a structural model for long-term potentiation | Physiological Reviews | 1995 | 175 |
27 | Role of D1 and D2 dopamine receptors in mediating locomotor activity elicited from the nucleus accumbens of rats | Brain Research | 1989 | 172 |
28 | The structure of a novel insecticidal neurotoxin, ω-atracotoxin-HV1, from the venom of an Australian funnel web spider | Nature Structural Biology | 1997 | 172 |
29 | Gingerols: a novel class of vanilloid receptor (VR1) agonists | British Journal of Pharmacology | 2002 | 171 |
30 | (+)- And (−)-borneol: efficacious positive modulators of GABA action at human recombinant α1β2γ2L GABAA receptors | Biochemical Pharmacology | 2005 | 170 |
31 | Actions of the ORL1Receptor Ligand Nociceptin on Membrane Properties of Rat Periaqueductal Gray NeuronsIn Vitro | Journal of Neuroscience | 1997 | 168 |
32 | Diazepam enhancement of low affinity GABA binding to rat brain membranes | Neuroscience Letters | 1982 | 166 |
33 | Enhanced Opioid Efficacy in Opioid Dependence Is Caused by an Altered Signal Transduction Pathway | Journal of Neuroscience | 1998 | 150 |
34 | The Production of Extracellular Matrix Proteins by Human Passively Sensitized Airway Smooth-Muscle Cells in Culture | American Journal of Respiratory and Critical Care Medicine | 2000 | 150 |
35 | Exhalation of respiratory viruses by breathing, coughing, and talking | Journal of Medical Virology | 2009 | 147 |
36 | Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus In vitro | Journal of Physiology | 2002 | 146 |
37 | Drug combinations and impaired renal function - the 'triple whammy' | British Journal of Clinical Pharmacology | 2005 | 146 |
38 | Opioid Agonists Have Different Efficacy Profiles for G Protein Activation, Rapid Desensitization, and Endocytosis of Mu-opioid Receptors | Journal of Biological Chemistry | 2003 | 142 |
39 | The Hepatic Sinusoid in Aging and Cirrhosis | Clinical Pharmacokinetics | 2005 | 140 |
40 | ATP - a fast neurotransmitter | FEBS Letters | 1993 | 137 |
41 | Localization of 3 H‐Dihydroergotamine‐binding sites in the cat central nervous system: Relevance to migraine | Annals of Neurology | 1991 | 135 |
42 | CXCR4 antagonists mobilize childhood acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment | Leukemia | 2007 | 135 |
43 | The dietary flavonoids apigenin and (−)-epigallocatechin gallate enhance the positive modulation by diazepam of the activation by GABA of recombinant GABAA receptors | Biochemical Pharmacology | 2004 | 129 |
44 | Cannabinoid receptor activation inhibits GABAergic neurotransmission in rostral ventromedial medulla neurons in vitro | British Journal of Pharmacology | 1999 | 124 |
45 | Adolescent Oxytocin Exposure Causes Persistent Reductions in Anxiety and Alcohol Consumption and Enhances Sociability in Rats | PLoS ONE | 2011 | 123 |
46 | Where is the locus in opioid withdrawal? | Trends in Pharmacological Sciences | 1997 | 122 |
47 | DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications | Trends in Pharmacological Sciences | 2015 | 122 |
48 | Expression of Connective Tissue Growth Factor in Asthmatic Airway Smooth Muscle Cells | American Journal of Respiratory and Critical Care Medicine | 2003 | 120 |
49 | Opioid inhibition of rat periaqueductal grey neurones with identified projections to rostral ventromedial medulla in vitro. | Journal of Physiology | 1996 | 118 |
50 | Extracellular Matrix Regulates Enhanced Eotaxin Expression in Asthmatic Airway Smooth Muscle Cells | American Journal of Respiratory and Critical Care Medicine | 2006 | 118 |