| # | Title | Journal | Year | Citations |
|---|
| 1 | Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study | Gastroenterology | 2021 | 913 |
| 2 | Nitric Oxide as a Bioregulator of Apoptosis | Biochemical and Biophysical Research Communications | 2001 | 483 |
| 3 | Sex Differences in Gut Microbiota | World Journal of Men?s Health | 2020 | 340 |
| 4 | Carbon Monoxide Produced by Heme Oxygenase-1 Suppresses T Cell Proliferation via Inhibition of IL-2 Production | Journal of Immunology | 2004 | 253 |
| 5 | Wharton’s Jelly-Derived Mesenchymal Stem Cells: Phenotypic Characterization and Optimizing Their Therapeutic Potential for Clinical Applications | International Journal of Molecular Sciences | 2013 | 247 |
| 6 | Hepatitis B Virus X Protein Induces Hepatic Steatosis Via Transcriptional Activation of SREBP1 and PPARγ | Gastroenterology | 2007 | 245 |
| 7 | PBMC and exosome-derived Hotair is a critical regulator and potent marker for rheumatoid arthritis | Clinical and Experimental Medicine | 2015 | 230 |
| 8 | Atrial Fibrillation Detection Using an iPhone 4S | IEEE Transactions on Biomedical Engineering | 2013 | 205 |
| 9 | Selective neuronal degeneration induced by soluble oligomeric amyloid beta‐protein | FASEB Journal | 2003 | 198 |
| 10 | Differential regulation of NO availability from macrophages and endothelial cells by the garlic component S-allyl cysteine | Free Radical Biology and Medicine | 2001 | 188 |
| 11 | Alpha-Pinene Exhibits Anti-Inflammatory Activity Through the Suppression of MAPKs and the NF-κB Pathway in Mouse Peritoneal Macrophages | The American Journal of Chinese Medicine | 2015 | 187 |
| 12 | Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion | Stroke | 2005 | 186 |
| 13 | DANCE MOVEMENT THERAPY IMPROVES EMOTIONAL RESPONSES AND MODULATES NEUROHORMONES IN ADOLESCENTS WITH MILD DEPRESSION | International Journal of Neuroscience | 2005 | 175 |
| 14 | Conventional and Kilohertz-frequency Spinal Cord Stimulation Produces Intensity- and Frequency-dependent Inhibition of Mechanical Hypersensitivity in a Rat Model of Neuropathic Pain | Anesthesiology | 2013 | 160 |
| 15 | Induction of apoptosis by diallyl disulfide through activation of caspase-3 in human leukemia HL-60 cells11Abbreviations: Ac-DEVD-CHO, N-acetyl-Asp-Glu-Val-Asp-CHO (aldehyde); Ac-DEVD-AFC, N-acetyl-Asp-Glu-Val-Asp-AFC (7-amino-4-trifluoromethyl-coumaine); Ac-YVAD-CHO, N-acetyl-Tyr-Val-Ala-Asp-CHO (aldehyde); CAD, caspase-activated deoxyribonuclease; CM-H2DCFDA, 5-(and -6)-chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate; DADS, diallyl disulfide; FACS, fluorescence-activated cell sorter; FITC, fluores | Biochemical Pharmacology | 2002 | 153 |
| 16 | The Increased Level of Depression and Anxiety in Irritable Bowel Syndrome Patients Compared with Healthy Controls: Systematic Review and Meta-analysis | Journal of Neurogastroenterology and Motility | 2017 | 146 |
| 17 | Nitric oxide prevents 6‐hydroxydopamine‐induced apoptosis in PC12 cells through cGMP‐dependent PI3 kinase/Akt activation | FASEB Journal | 2003 | 145 |
| 18 | Critical role of heme oxygenase-1 in Foxp3-mediated immune suppression | Biochemical and Biophysical Research Communications | 2005 | 141 |
| 19 | Update on FXR Biology: Promising Therapeutic Target? | International Journal of Molecular Sciences | 2018 | 138 |
| 20 | Endothelial progenitor cell homing: prominent role of the IGF2-IGF2R-PLCβ2 axis | Blood | 2009 | 136 |
| 21 | Anti-inflammatory activity of fisetin in human mast cells (HMC-1) | Pharmacological Research | 2007 | 127 |
| 22 | GM-CSF Regulates Fusion of Mononuclear Osteoclasts into Bone-Resorbing Osteoclasts by Activating the Ras/ERK Pathway | Journal of Immunology | 2009 | 116 |
| 23 | The human lysyl oxidase-like 2 protein functions as an amine oxidase toward collagen and elastin | Molecular Biology Reports | 2011 | 103 |
| 24 | Water-soluble chitosan inhibits the production of pro-inflammatory cytokine in human astrocytoma cells activated by amyloid β peptide and interleukin-1β | Neuroscience Letters | 2002 | 97 |
| 25 | Suppression of Nrf2-driven heme oxygenase-1 enhances the chemosensitivity of lung cancer A549 cells toward cisplatin | Lung Cancer | 2008 | 97 |
| 26 | Characteristics of CADASIL in Korea | Neurology | 2006 | 94 |
| 27 | Heme Oxygenase-1: Its Therapeutic Roles in Inflammatory Diseases | Immune Network | 2009 | 94 |
| 28 | Growth Retardation of Inner Cell Mass Cells in Polyspermic Porcine Embryos Produced In Vitro1 | Biology of Reproduction | 1999 | 93 |
| 29 | Smartphone-Based Fluorescent Diagnostic System for Highly Pathogenic H5N1 Viruses | Theranostics | 2016 | 91 |
| 30 | Pulmonary actinomycosis during the first decade of 21st century: cases of 94 patients | BMC Infectious Diseases | 2013 | 90 |
| 31 | Phyco-synthesis of Silver Nanoparticles Mediated from Marine Algae Sargassum myriocystum and Its Potential Biological and Environmental Applications | Waste and Biomass Valorization | 2020 | 89 |
| 32 | Nitric Oxide is a Regulator of Bone Remodelling | Journal of Pharmacy and Pharmacology | 2011 | 88 |
| 33 | AIM2 inflammasome contributes to brain injury and chronic post-stroke cognitive impairment in mice | Brain, Behavior, and Immunity | 2020 | 86 |
| 34 | QIGONG REDUCED BLOOD PRESSURE AND CATECHOLAMINE LEVELS OF PATIENTS WITH ESSENTIAL HYPERTENSION | International Journal of Neuroscience | 2003 | 85 |
| 35 | Can a small endoscopic sphincterotomy plus a large-balloon dilation reduce the use of mechanical lithotripsy in patients with large bile duct stones? | Surgical Endoscopy and Other Interventional Techniques | 2011 | 85 |
| 36 | Experience-Dependent Induction of Hippocampal ΔFosB Controls Learning | Journal of Neuroscience | 2015 | 85 |
| 37 | Current trends and future projections of hip fracture in South Korea using nationwide claims data | Osteoporosis International | 2016 | 83 |
| 38 | 20(S)-Protopanaxatriol, one of ginsenoside metabolites, inhibits inducible nitric oxide synthase and cyclooxygenase-2 expressions through inactivation of nuclear factor-κB in RAW 264.7 macrophages stimulated with lipopolysaccharide | Cancer Letters | 2004 | 82 |
| 39 | Berberine-Induced Apoptosis in Human Glioblastoma T98G Cells Is Mediated by Endoplasmic Reticulum Stress Accompanying Reactive Oxygen Species and Mitochondrial Dysfunction | Biological and Pharmaceutical Bulletin | 2010 | 82 |
| 40 | TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse | Journal of Cell Biology | 2015 | 78 |
| 41 | Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells | Journal of Translational Medicine | 2017 | 78 |
| 42 | Integrative Survival Response Evoked by Heme Oxygenase-1 and Heme Metabolites | Journal of Clinical Biochemistry and Nutrition | 2008 | 72 |
| 43 | Hepatoprotective Effect of Baicalin, a Major Flavone fromScutellaria radix, on Acetaminophen‐Induced Liver Injury in Mice | Immunopharmacology and Immunotoxicology | 2003 | 71 |
| 44 | Nitric oxide priming protects nitric oxide-mediated apoptosis via HEME OXYGENASE-1 induction | Free Radical Biology and Medicine | 2003 | 70 |
| 45 | Anabolic activity of ursolic acid in bone: Stimulating osteoblast differentiation in vitro and inducing new bone formation in vivo | Pharmacological Research | 2008 | 70 |
| 46 | Effects of nicotine on proliferation and osteoblast differentiation in human alveolar bone marrow-derived mesenchymal stem cells | Life Sciences | 2012 | 68 |
| 47 | Acupuncture points can be identified as cutaneous neurogenic inflammatory spots | Scientific Reports | 2017 | 68 |
| 48 | Iron Chelator Triggers Inflammatory Signals in Human Intestinal Epithelial Cells: Involvement of p38 and Extracellular Signal-Regulated Kinase Signaling Pathways | Journal of Immunology | 2004 | 67 |
| 49 | Berberine Induces G1 Arrest and Apoptosis in Human Glioblastoma T98G Cells through Mitochondrial/Caspases Pathway | Biological and Pharmaceutical Bulletin | 2008 | 66 |
| 50 | Endoscopic ultrasound-guided biliary drainage with placement of a fully covered metal stent for malignant biliary obstruction | World Journal of Gastroenterology | 2012 | 66 |
