| # | Title | Journal | Year | Citations |
|---|
| 1 | Antimutagenic activity of flavonoids from the heartwood of Rhus verniciflua | Journal of Ethnopharmacology | 2004 | 164 |
| 2 | Inhibitory effects of Nelumbo nucifera leaves on rat lens aldose reductase, advanced glycation endproducts formation, and oxidative stress | Food and Chemical Toxicology | 2008 | 111 |
| 3 | Hepatoprotective effects of bergenin, a major constituent of Mallotus japonicus, on carbon tetrachloride-intoxicated rats | Journal of Ethnopharmacology | 2000 | 101 |
| 4 | Anti-Inflammatory and Antinociceptive Effects of Sinapyl Alcohol and its Glucoside Syringin | Planta Medica | 2004 | 98 |
| 5 | Pectolinarin and Pectolinarigenin of Cirsium setidens Prevent the Hepatic Injury in Rats Caused by D-Galactosamine via an Antioxidant Mechanism | Biological and Pharmaceutical Bulletin | 2008 | 97 |
| 6 | Anti-inflammatory effect of buddlejasaponin IV through the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via the NF-κ B inactivation | British Journal of Pharmacology | 2006 | 95 |
| 7 | Antinociceptive Anti-inflammatory Effect of Monotropein Isolated from the Root of Morinda officinalis | Biological and Pharmaceutical Bulletin | 2005 | 88 |
| 8 | Acteoside inhibits human promyelocytic HL-60 leukemia cell proliferation via inducing cell cycle arrest at G0/G1 phase and differentiation into monocyte | Carcinogenesis | 2007 | 86 |
| 9 | Antinociceptive and Antiinflammatory Effects of Niga-ichigoside F1 and 23-Hydroxytormentic Acid Obtained from Rubus coreanus | Biological and Pharmaceutical Bulletin | 2003 | 85 |
| 10 | PEGylation of Octreotide: I. Separation of Positional Isomers and Stability Against Acylation by Poly(D,L-lactide-co-glycolide) | Pharmaceutical Research | 2005 | 85 |
| 11 | Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozotocin-induced diabetic rat and their antioxidant activityin vitro | Archives of Pharmacal Research | 2000 | 83 |
| 12 | Constituents of the essential oil of theCinnamomum cassia stem bark and the Biological Properties | Archives of Pharmacal Research | 2001 | 82 |
| 13 | Antinociceptive and Anti-Inflammatory Effects of the Saponin and Sapogenins Obtained from the Stem of Akebia quinata | Journal of Medicinal Food | 2005 | 81 |
| 14 | Long-acting injectable formulations of antipsychotic drugs for the treatment of schizophrenia | Archives of Pharmacal Research | 2013 | 81 |
| 15 | Evaluation of metabolism-mediated herb-drug interactions | Archives of Pharmacal Research | 2011 | 78 |
| 16 | Improved intrapulmonary delivery of site-specific PEGylated salmon calcitonin: Optimization by PEG size selection | Journal of Controlled Release | 2008 | 71 |
| 17 | Structure-Activity Relationship of Oleanane Disaccharides Isolated from Akebia quinata versus Cytotoxicity against Cancer Cells and NO Inhibition | Biological and Pharmaceutical Bulletin | 2004 | 69 |
| 18 | PEGylation of Octreotide: II. Effect of N-terminal Mono-PEGylation on Biological Activity and Pharmacokinetics | Pharmaceutical Research | 2005 | 69 |
| 19 | Antiinflammatory effects of chiisanoside and chiisanogenin obtained from the leaves of Acanthopanax chiisanensis in the carrageenan- and Freund's complete adjuvant-induced rats | Journal of Ethnopharmacology | 2005 | 68 |
| 20 | Antinociceptive and anti-rheumatoidal effects of Kalopanax pictus extract and its saponin components in experimental animals | Journal of Ethnopharmacology | 2002 | 65 |
| 21 | A potent anti-diabetic agent fromKalopanax pictus | Archives of Pharmacal Research | 1998 | 64 |
| 22 | Dose-dependent effects of cisplatin on the severity of testicular injury in Sprague Dawley rats: reactive oxygen species and endoplasmic reticulum stress | Drug Design, Development and Therapy | 2016 | 63 |
| 23 | Effect of sex hormones on lipid peroxidation in rat liver | Archives of Pharmacal Research | 1994 | 62 |
| 24 | Preparation and Evaluation of Solid Dispersion of Atorvastatin Calcium with Soluplus® by Spray Drying Technique | Chemical and Pharmaceutical Bulletin | 2014 | 62 |
| 25 | Epithelial-mesenchymal Transition is Associated with Acquired Resistance to 5-Fluorocuracil in HT-29 Colon Cancer Cells | Toxicological Research | 2015 | 61 |
| 26 | Effects of acetylbergenin against D -galactosamine-induced hepatotoxicity in rats | Pharmacological Research | 2000 | 57 |
| 27 | 19.ALPHA.-Hydroxyursane-Type Triterpenoids: Antinociceptive Anti-inflammatory Principles of the Roots of Rosa rugosa | Biological and Pharmaceutical Bulletin | 2005 | 57 |
| 28 | The Effects of Calorie Restriction on Autophagy: Role on Aging Intervention | Nutrients | 2019 | 56 |
| 29 | Formation of acylated growth hormone-releasing peptide-6 by poly(lactide-co-glycolide) and its biological activity | AAPS PharmSciTech | 2007 | 49 |
| 30 | Design, synthesis, and biological evaluation of benzofuran- and 2,3-dihydrobenzofuran-2-carboxylic acid N-(substituted)phenylamide derivatives as anticancer agents and inhibitors of NF-κB | Bioorganic and Medicinal Chemistry Letters | 2015 | 49 |
| 31 | The Role of Endoplasmic Reticulum Stress Response in Male Reproductive Physiology and Pathology: A Review | World Journal of Men?s Health | 2020 | 49 |
| 32 | Stability of Antimicrobial Decapeptide (KSL) and Its Analogues for Delivery in the Oral Cavity | Pharmaceutical Research | 2007 | 47 |
| 33 | Antirheumatoid Arthritis Effect ofRhus vernicifluaand of the Active Component, Sulfuretin | Planta Medica | 2003 | 46 |
| 34 | Methanol Extract of Xanthium strumarium L. Possesses Anti-inflammatory and Anti-nociceptive Activities | Biological and Pharmaceutical Bulletin | 2005 | 46 |
| 35 | In VivoAntihepatotoxic Effects ofLigularia fischerivar.spiciformisand the Identification of the Active Component, 3,4-Dicaffeoylquinic Acid | Journal of Medicinal Food | 2005 | 46 |
| 36 | Momordin Ic and Oleanolic Acid from Kochiae Fructus Reduce Carbon Tetrachloride-Induced Hepatotoxicity in Rats | Journal of Medicinal Food | 2005 | 44 |
| 37 | Fabrication and evaluation of valsartan–polymer–surfactant composite nanoparticles by using the supercritical antisolvent process | International Journal of Nanomedicine | 2014 | 43 |
| 38 | Synthesis and Biological Evaluation of Novel Thiazolidinedione Analogues as 15-Hydroxyprostaglandin Dehydrogenase Inhibitors | Journal of Medicinal Chemistry | 2011 | 42 |
| 39 | Drug release testing methods of polymeric particulate drug formulations | Journal of Pharmaceutical Investigation | 2013 | 42 |
| 40 | <p>Intravesical delivery of rapamycin via folate-modified liposomes dispersed in thermo-reversible hydrogel</p> | International Journal of Nanomedicine | 2019 | 42 |
| 41 | Anti-rheumatoid arthritis effect of theKochia scoparia fruits and activity comparison of momordin ic, its prosapogenin and sapogenin | Archives of Pharmacal Research | 2002 | 40 |
| 42 | Formulation, Characterization, and in Vivo Evaluation of Celecoxib-PVP Solid Dispersion Nanoparticles Using Supercritical Antisolvent Process | Molecules | 2014 | 40 |
| 43 | The ameliorative effect of monotropein, astragalin, and spiraeoside on oxidative stress, endoplasmic reticulum stress, and mitochondrial signaling pathway in varicocelized rats | BMC Complementary and Alternative Medicine | 2019 | 39 |
| 44 | Chewing gum of antimicrobial decapeptide (KSL) as a sustained antiplaque agent: Preformulation study | Journal of Controlled Release | 2005 | 38 |
| 45 | Anti-ulcerogenic Effect and HPLC Analysis of the Caffeoylquinic Acid-Rich Extract from Ligularia stenocephala | Biological and Pharmaceutical Bulletin | 2010 | 38 |
| 46 | In vivo sedative and gastroprotective activities of Salvia plebeia extract and its composition of polyphenols | Archives of Pharmacal Research | 2012 | 38 |
| 47 | Preparation and Evaluation of Resveratrol-Loaded Composite Nanoparticles Using a Supercritical Fluid Technology for Enhanced Oral and Skin Delivery | Antioxidants | 2019 | 37 |
| 48 | The Effect of Schisandra chinensis Baillon on Cross-Talk between Oxidative Stress, Endoplasmic Reticulum Stress, and Mitochondrial Signaling Pathway in Testes of Varicocele-Induced SD Rat | International Journal of Molecular Sciences | 2019 | 37 |
| 49 | Anti-inflammatory and Anti-nociceptive Effects of the Methanol Extract of Fomes fomentarius | Biological and Pharmaceutical Bulletin | 2004 | 36 |
| 50 | Design and synthesis of 6-amino-1,4-oxazepane-3,5-dione derivatives as novel broad spectrum anticonvulsants | Bioorganic and Medicinal Chemistry Letters | 2008 | 36 |
