| # | Title | Journal | Year | Citations |
|---|
| 1 | Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS) | British Journal of Pharmacology | 2011 | 1,082 |
| 2 | Association between pathological and MRI findings in multiple sclerosis | Lancet Neurology, The | 2012 | 356 |
| 3 | Fatigue in multiple sclerosis — A brief review | Journal of the Neurological Sciences | 2012 | 183 |
| 4 | A prospective study of conditions associated with multiple sclerosis in a cohort of 658 consecutive outpatients attending a multiple sclerosis clinic | Multiple Sclerosis Journal | 2004 | 182 |
| 5 | Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus | Nature Genetics | 2006 | 180 |
| 6 | Validation of the Multiple Sclerosis International Quality of Life questionnaire | Multiple Sclerosis Journal | 2008 | 159 |
| 7 | TLR2 Stimulation Drives Human Naive and Effector Regulatory T Cells into a Th17-Like Phenotype with Reduced Suppressive Function | Journal of Immunology | 2011 | 152 |
| 8 | Functional magnetic resonance imaging of single motor events reveals human presupplementary motor area | Annals of Neurology | 1997 | 136 |
| 9 | Spinal cord atrophy and disability in multiple sclerosis over four years: application of a reproducible automated technique in monitoring disease progression in a cohort of the interferon -1a (Rebif) treatment trial | Journal of Neurology, Neurosurgery and Psychiatry | 2003 | 122 |
| 10 | Pyramidal tract mapping by diffusion tensor magnetic resonance imaging in multiple sclerosis: improving correlations with disability | Journal of Neurology, Neurosurgery and Psychiatry | 2003 | 117 |
| 11 | Infratentorial atrophy on magnetic resonance imaging and disability in multiple sclerosis | Brain | 1999 | 106 |
| 12 | fMRI analysis of active, passive and electrically stimulated ankle dorsiflexion | NeuroImage | 2009 | 106 |
| 13 | ‘Importance sampling’ in MS: Use of diffusion tensor tractography to quantify pathology related to specific impairment | Journal of the Neurological Sciences | 2005 | 86 |
| 14 | Neurofilament ELISA validation | Journal of Immunological Methods | 2010 | 86 |
| 15 | Central Veins in Brain Lesions Visualized With High-Field Magnetic Resonance Imaging | JAMA Neurology | 2013 | 78 |
| 16 | CNS-specific Therapy for Ongoing EAE by Silencing IL-17 Pathway in Astrocytes | Molecular Therapy | 2012 | 72 |
| 17 | The relationship of brain and cervical cord volume to disability in clinical subtypes of multiple sclerosis: a three-dimensional MRI study | Acta Neurologica Scandinavica | 2003 | 66 |
| 18 | Curcumin modulation of IFN‐β and IL‐12 signalling and cytokine induction in human T cells | Journal of Cellular and Molecular Medicine | 2007 | 65 |
| 19 | Measurement of Spinal Cord Atrophy in Multiple Sclerosis | Journal of Neuroimaging | 2004 | 63 |
| 20 | Evaluation of an adjustment group forpeople with multiple sclerosis and lowmood: a randomized controlled trial | Multiple Sclerosis Journal | 2011 | 62 |
| 21 | Stroop performance in multiple sclerosis: Information processing, selective attention, or executive functioning? | Journal of the International Neuropsychological Society | 2008 | 61 |
| 22 | Cognitive correlates of supratentorial atrophy on MRI in multiple sclerosis | Acta Neurologica Scandinavica | 2001 | 60 |
| 23 | Role of the Innate Immune System in Autoimmune Inflammatory Demyelination | Current Medicinal Chemistry | 2008 | 60 |
| 24 | Which antibody and which cancer in which paraneoplastic syndromes? | Practical Neurology | 2010 | 59 |
| 25 | Measurement of cervical spinal cord cross-sectional area by MRI using edge detection and partial volume correction | Journal of Magnetic Resonance Imaging | 2005 | 58 |
| 26 | Brain tractography using Q-ball imaging and graph theory: Improved connectivities through fibre crossings via a model-based approach | NeuroImage | 2010 | 56 |
| 27 | Detecting activations in event-related fMRI using analysis of variance | Magnetic Resonance in Medicine | 1999 | 54 |
| 28 | Are current disease‐modifying therapeutics in multiple sclerosis justified on the basis of studies in experimental autoimmune encephalomyelitis? | Journal of Neurochemistry | 2010 | 51 |
| 29 | Increased Osteopontin Levels in the Cerebrospinal Fluid of Patients With Multiple Sclerosis | Archives of Neurology | 2008 | 50 |
| 30 | Measurement of Spinal Cord Atrophy in Multiple Sclerosis | | 2004 | 46 |
| 31 | Impact of exposure to interferon beta-1a on outcomes in patients with relapsing–remitting multiple sclerosis: exploratory analyses from the PRISMS long-term follow-up study | Therapeutic Advances in Neurological Disorders | 2011 | 45 |
| 32 | Current and future disease-modifying therapies in multiple sclerosis | International Journal of Clinical Practice | 2010 | 44 |
| 33 | Platelet Activating Factor/Platelet Activating Factor Receptor Pathway as a Potential Therapeutic Target in Autoimmune Diseases | Inflammation and Allergy: Drug Targets | 2009 | 43 |
| 34 | Spinal Cord Imaging in Multiple Sclerosis | Journal of Neuroimaging | 2005 | 41 |
| 35 | Identification of the Synthetic Cannabinoid R(+)WIN55,212-2 as a Novel Regulator of IFN Regulatory Factor 3 Activation and IFN-β Expression | Journal of Biological Chemistry | 2011 | 39 |
| 36 | Focal multiple sclerosis lesions abound in ‘normal appearing white matter’ | Multiple Sclerosis Journal | 2011 | 39 |
| 37 | The Role of Osteopontin in Experimental Autoimmune Encephalomyelitis (EAE) and Multiple Sclerosis (MS) | Inflammation and Allergy: Drug Targets | 2010 | 38 |
| 38 | Validating the portal population of the United Kingdom Multiple Sclerosis Register | Multiple Sclerosis and Related Disorders | 2018 | 38 |
| 39 | Upper cervical spinal cord cross‐sectional area in relapsing remitting multiple sclerosis: Application of a new technique for measuring cross‐sectional area on magnetic resonance images | Journal of Magnetic Resonance Imaging | 2007 | 37 |
| 40 | Expression of Activity-Dependent Neuroprotective Protein in the Immune System: Possible Functions and Relevance to Multiple Sclerosis | NeuroImmunoModulation | 2010 | 37 |
| 41 | Increase in the iron content of the substantia nigra and red nucleus in multiple sclerosis and clinically isolated syndrome: A 7 Tesla MRI study | Journal of Magnetic Resonance Imaging | 2015 | 37 |
| 42 | Spotlight on teriflunomide | International MS Journal | 2008 | 36 |
| 43 | The TLR7 agonist, imiquimod, increases IFN-β production and reduces the severity of experimental autoimmune encephalomyelitis | Journal of Neuroimmunology | 2010 | 34 |
| 44 | Cannabinoids and experimental models of multiple sclerosis | Immunobiology | 2010 | 33 |
| 45 | A regularized two‐tensor model fit to low angular resolution diffusion images using basis directions | Journal of Magnetic Resonance Imaging | 2008 | 31 |
| 46 | Modulation of Regulatory T Cells in Health and Disease: Role of Toll-Like Receptors | Inflammation and Allergy: Drug Targets | 2009 | 30 |
| 47 | Orexin A (hypocretin-1) levels are not reduced while cocaine/amphetamine regulated transcript levels are increased in the cerebrospinal fluid of patients with multiple sclerosis: No correlation with fatigue and sleepiness | Journal of the Neurological Sciences | 2011 | 29 |
| 48 | Reciprocal Regulation of Substance P and IL-12/IL-23 and the Associated Cytokines, IFNγ/IL-17: A Perspective on the Relevance of This Interaction to Multiple Sclerosis | Journal of NeuroImmune Pharmacology | 2015 | 28 |
| 49 | Effects of glucocorticoids on STAT4 activation in human T cells are stimulus-dependent | Journal of Leukocyte Biology | 2006 | 27 |
| 50 | T-cell based immunotherapy in experimental autoimmune encephalomyelitis and multiple sclerosis | Immunotherapy | 2010 | 25 |
