| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 2 | Role of the gut microbiota in nutrition and health | BMJ: British Medical Journal | 2018 | 1,228 |
| 3 | The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes | Nature Communications | 2016 | 1,221 |
| 4 | Global epidemiology of gout: prevalence, incidence and risk factors | Nature Reviews Rheumatology | 2015 | 854 |
| 5 | Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score | BMJ, The | 2020 | 779 |
| 6 | Origins of lifetime health around the time of conception: causes and consequences | Lancet, The | 2018 | 771 |
| 7 | The STROCSS statement: Strengthening the Reporting of Cohort Studies in Surgery | International Journal of Surgery | 2017 | 727 |
| 8 | Global epidemiology and outcomes of acute kidney injury | Nature Reviews Nephrology | 2018 | 698 |
| 9 | The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data | Brain Imaging and Behavior | 2014 | 696 |
| 10 | Global incidence and mortality of idiopathic pulmonary fibrosis: a systematic review | European Respiratory Journal | 2015 | 638 |
| 11 | Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study | Lancet, The | 2022 | 547 |
| 12 | Annual Research Review: Digital health interventions for children and young people with mental health problems – a systematic and meta‐review | Journal of Child Psychology and Psychiatry and Allied Disciplines | 2017 | 546 |
| 13 | A systematic review of the reporting of tinnitus prevalence and severity | Hearing Research | 2016 | 493 |
| 14 | Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals | Nature Medicine | 2021 | 477 |
| 15 | Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study | Annals of the Rheumatic Diseases | 2015 | 472 |
| 16 | Living risk prediction algorithm (QCOVID) for risk of hospital admission and mortality from coronavirus 19 in adults: national derivation and validation cohort study | BMJ, The | 2020 | 471 |
| 17 | Ethnicity and clinical outcomes in COVID-19: A systematic review and meta-analysis | EClinicalMedicine | 2020 | 454 |
| 18 | Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1 | American Journal of Medical Genetics, Part A | 2015 | 447 |
| 19 | ISUOG Practice Guidelines: role of ultrasound in twin pregnancy | Ultrasound in Obstetrics and Gynecology | 2016 | 445 |
| 20 | Fulvestrant 500 mg versus anastrozole 1 mg for hormone receptor-positive advanced breast cancer (FALCON): an international, randomised, double-blind, phase 3 trial | Lancet, The | 2016 | 435 |
| 21 | Consensus guidelines for the use and interpretation of angiogenesis assays | Angiogenesis | 2018 | 429 |
| 22 | Human postprandial responses to food and potential for precision nutrition | Nature Medicine | 2020 | 418 |
| 23 | Computer-Delivered and Web-Based Interventions to Improve Depression, Anxiety, and Psychological Well-Being of University Students: A Systematic Review and Meta-Analysis | Journal of Medical Internet Research | 2014 | 404 |
| 24 | The age-related loss of skeletal muscle mass and function: Measurement and physiology of muscle fibre atrophy and muscle fibre loss in humans | Ageing Research Reviews | 2018 | 390 |
| 25 | A meta-analysis of self-determination theory-informed intervention studies in the health domain: effects on motivation, health behavior, physical, and psychological health | Health Psychology Review | 2021 | 374 |
| 26 | Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank | Lancet Respiratory Medicine,the | 2015 | 346 |
| 27 | In-Hospital Mortality after Surgical Lung Biopsy for Interstitial Lung Disease in the United States. 2000 to 2011 | American Journal of Respiratory and Critical Care Medicine | 2016 | 345 |
| 28 | An update on PPAR activation by cannabinoids | British Journal of Pharmacology | 2016 | 333 |
| 29 | A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans | Frontiers in Pharmacology | 2018 | 326 |
| 30 | Stress and Health: A Review of Psychobiological Processes | Annual Review of Psychology | 2021 | 305 |
| 31 | Prevalence, severity, and nature of preventable patient harm across medical care settings: systematic review and meta-analysis | BMJ: British Medical Journal | 2019 | 304 |
| 32 | Incidence and prevalence of patellofemoral pain: A systematic review and meta-analysis | PLoS ONE | 2018 | 301 |
| 33 | Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people | Heart | 2020 | 297 |
| 34 | Behavioral Interventions in Attention-Deficit/Hyperactivity Disorder: A Meta-Analysis of Randomized Controlled Trials Across Multiple Outcome Domains | Journal of the American Academy of Child and Adolescent Psychiatry | 2014 | 288 |
| 35 | Guidelines on the management of ascites in cirrhosis | Gut | 2021 | 280 |
| 36 | 2018 update of the EULAR recommendations for the management of hand osteoarthritis | Annals of the Rheumatic Diseases | 2019 | 273 |
| 37 | World guidelines for falls prevention and management for older adults: a global initiative | Age and Ageing | 2022 | 263 |
| 38 | An overview of technical considerations for Western blotting applications to physiological research | Scandinavian Journal of Medicine and Science in Sports | 2017 | 255 |
| 39 | The ‘Swallow Tail’ Appearance of the Healthy Nigrosome – A New Accurate Test of Parkinson's Disease: A Case-Control and Retrospective Cross-Sectional MRI Study at 3T | PLoS ONE | 2014 | 252 |
| 40 | Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups | Nature | 2019 | 239 |
| 41 | Efficacy and cost-effectiveness of nurse-led care involving education and engagement of patients and a treat-to-target urate-lowering strategy versus usual care for gout: a randomised controlled trial | Lancet, The | 2018 | 235 |
| 42 | Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations | Frontiers in Physiology | 2017 | 226 |
| 43 | The development and validation of the Comprehensive assessment of Acceptance and Commitment Therapy processes (CompACT) | Journal of Contextual Behavioral Science | 2016 | 225 |
| 44 | Food insecurity and mental health: a systematic review and meta-analysis | Public Health Nutrition | 2020 | 225 |
| 45 | Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families | JAMA Internal Medicine | 2015 | 221 |
| 46 | Muscle Ultrasound and Sarcopenia in Older Individuals: A Clinical Perspective | Journal of the American Medical Directors Association | 2017 | 212 |
| 47 | Maternal transmission of SARS‐COV‐2 to the neonate, and possible routes for such transmission: a systematic review and critical analysis | BJOG: an International Journal of Obstetrics and Gynaecology | 2020 | 208 |
| 48 | Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: national prospective cohort study | BMJ, The | 2021 | 208 |
| 49 | A multi-layer network approach to MEG connectivity analysis | NeuroImage | 2016 | 205 |
| 50 | Preventing dementia by preventing stroke: The Berlin Manifesto | Alzheimer's and Dementia | 2019 | 200 |
