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#TitleJournalYearCitations
1Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone DensityCell19974,620
2The Osteoclast Differentiation Factor Osteoprotegerin-Ligand Is Essential for Mammary Gland DevelopmentCell2000674
3Control of Peripheral Nerve Myelination by the ß-Secretase BACE1Science2006652
4The Ligand for Osteoprotegerin (OPGL) Directly Activates Mature OsteoclastsJournal of Cell Biology1999634
5Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-bNature2000623
6RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesisNature2010510
7Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos diseaseNature Genetics2001451
8RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriersNature Medicine2016224
9Embryonic cardiomyocyte hypoplasia and craniofacial defects in Galpha q/Galpha 11-mutant miceEMBO Journal1998216
10Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasisClinical and Experimental Metastasis2008193
11Pharmacologic Effects of FGF21 Are Independent of the “Browning” of White Adipose TissueCell Metabolism2015172
12Association of K-ras Mutational Status and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Receiving Panitumumab AloneClinical Colorectal Cancer2008147
13Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor ActivityCancer Cell2014137
14Macroscopic cartilage formation with embryonic stem-cell-derived mesodermal progenitor cellsJournal of Cell Science2003136
15Global Nav1.7 Knockout Mice Recapitulate the Phenotype of Human Congenital Indifference to PainPLoS ONE2014135
16c-Met Inhibitors with Novel Binding Mode Show Activity against Several Hereditary Papillary Renal Cell Carcinoma-related MutationsJournal of Biological Chemistry2008131
17SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxiaOncogene2003130
18FGF21 Promotes Metabolic Homeostasis via White Adipose and Leptin in MicePLoS ONE2012127
19Growth factors and cytokines in hair follicle development and cycling: recent insights from animal models and the potentials for clinical therapyTrends in Molecular Medicine1996117
20Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formation from human peripheral blood mononuclear cell precursorsJournal of Cellular Biochemistry1999116
21Systemically and Topically Administered Leptin Both Accelerate Wound Healing in Diabetic ob/ob MiceEndocrinology2000115
22The MDM2 Inhibitor AMG 232 Demonstrates Robust Antitumor Efficacy and Potentiates the Activity of p53-Inducing Cytotoxic AgentsMolecular Cancer Therapeutics2015112
23Osteoprotegerin prevents and reverses hypercalcemia in a murine model of humoral hypercalcemia of malignancyCancer Research2000109
24Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injuryJournal of Bone and Mineral Research2011106
25The effects of keratinocyte growth factor in preclinical models of mucositisCell Proliferation2002100
26Effects of keratinocyte growth factor in the squamous epithelium of the upper aerodigestive tract of normal and irradiated miceInternational Journal of Radiation Biology199995
27RANKL is a Marker and Mediator of Local and Systemic Bone Loss in Two Rat Models of Inflammatory ArthritisJournal of Bone and Mineral Research200594
28Rodent Preclinical Models for Developing Novel Antiarthritic Molecules: Comparative Biology and Preferred Methods for Evaluating EfficacyJournal of Biomedicine and Biotechnology201192
29Osteoclast markers accumulate on cells developing from human peripheral blood mononuclear precursors199991
30Myofibroblast and α1(III) collagen expression in experimental tubulointerstitial nephritisKidney International199778
31RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFα or anti-IL-1 therapiesArthritis Research and Therapy200975
32Best practices for veterinary toxicologic clinical pathology, with emphasis on the pharmaceutical and biotechnology industriesVeterinary Clinical Pathology201362
33RANK expression as a prognostic and predictive marker in breast cancerBreast Cancer Research and Treatment201459
34Chemokine expression in experimental tubulointerstitial nephritis.Journal of Immunology199758
35The Stress Kinase Mitogen-Activated Protein Kinase Kinase (Mkk)7 Is a Negative Regulator of Antigen Receptor and Growth Factor Receptor–Induced Proliferation in Hematopoietic CellsJournal of Experimental Medicine200156
36Deregulation of Cyclin E2 expression and associated kinase activity in primary breast tumorsOncogene200249
37A comparability study of 5 commercial KRAS testsDiagnostic Pathology201047
38RANK and RANK ligand expression in primary human osteosarcomaJournal of Bone Oncology201547
39Chemokine expression in experimental tubulointerstitial nephritisJournal of Immunology199747
40Trefoil peptide expression and goblet cell number in rat intestine: effects of KGF and fasting-refeedingAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology200344
41Evaluation of pharmacodynamic biomarkers in a Phase 1a trial of dulanermin (rhApo2L/TRAIL) in patients with advanced tumoursBritish Journal of Cancer201142
42Inhibition of RANKL increases the anti-tumor effect of the EGFR inhibitor panitumumab in a murine model of bone metastasisBone201040
43Isoflurane leakage from non-rebreathing rodent anaesthesia circuits: comparison of emissions from conventional and modified portsLaboratory Animals200639
44The Candidate Neuroprotective Agent Artemin Induces Autonomic Neural Dysplasia without Preventing Peripheral Nerve DysfunctionToxicologic Pathology200438
45Antidiabetic effects of 11β‐HSD1 inhibition in a mouse model of combined diabetes, dyslipidaemia and atherosclerosisDiabetes, Obesity and Metabolism200934
46The role of interferon-gamma, nitric oxide and lipopolysaccharide in intestinal graft-versus-host disease developing in F1-hybrid miceImmunology200333
47RANKL inhibition combined with tamoxifen treatment increases anti-tumor efficacy and prevents tumor-induced bone destruction in an estrogen receptor-positive breast cancer bone metastasis modelBreast Cancer Research and Treatment201233
48Expression of anti-apoptotic factors modulates Apo2L/TRAIL resistance in colon carcinoma cellsApoptosis: an International Journal on Programmed Cell Death200731
49Potent activity of soluble B7RP-1-Fc in therapy of murine tumors in syngeneic hostsInternational Journal of Cancer200328
50Peroxisome Proliferators and Receptor-Mediated Hepatic CarcinogenesisToxicologic Pathology200428