| # | Title | Journal | Year | Citations |
|---|
| 1 | Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain | Biochemical Journal | 2000 | 1,762 |
| 2 | Bioregulation of kinins: kallikreins, kininogens, and kininases | Pharmacological Reviews | 1992 | 1,391 |
| 3 | Metallo-β-Lactamases: the Quiet before the Storm? | Clinical Microbiology Reviews | 2005 | 1,283 |
| 4 | Real-time, portable genome sequencing for Ebola surveillance | Nature | 2016 | 1,179 |
| 5 | Inflammatory cells during wound repair: the good, the bad and the ugly | Trends in Cell Biology | 2005 | 1,141 |
| 6 | The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation | Biochemical Journal | 1999 | 1,138 |
| 7 | Light Microscopy Techniques for Live Cell Imaging | Science | 2003 | 1,127 |
| 8 | Structure and Mechanism of Helicases and Nucleic Acid Translocases | Annual Review of Biochemistry | 2007 | 1,098 |
| 9 | Membrane proteins, lipids and detergents: not just a soap opera | Biochimica Et Biophysica Acta - Biomembranes | 2004 | 1,080 |
| 10 | Excitatory amino acid receptors and synaptic plasticity | Trends in Pharmacological Sciences | 1990 | 835 |
| 11 | How do site-specific DNA-binding proteins find their targets? | Nucleic Acids Research | 2004 | 813 |
| 12 | Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain | Biochemical Journal | 2000 | 810 |
| 13 | What is the mitochondrial permeability transition pore? | Journal of Molecular and Cellular Cardiology | 2009 | 797 |
| 14 | Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion | Biochemical Journal | 1995 | 778 |
| 15 | Descending control of nociception: Specificity, recruitment and plasticity | Brain Research Reviews | 2009 | 760 |
| 16 | Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament | Biophysical Journal | 1993 | 757 |
| 17 | Prion protein is necessary for normal synaptic function | Nature | 1994 | 748 |
| 18 | The Plasma Membrane Lactate Transporter MCT4, but Not MCT1, Is Up-regulated by Hypoxia through a HIF-1α-dependent Mechanism | Journal of Biological Chemistry | 2006 | 738 |
| 19 | Inhibition of Ca2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adenine nucleotide translocase | Biochemical Journal | 1990 | 714 |
| 20 | Regulation of mitochondrial dehydrogenases by calcium ions | Biochimica Et Biophysica Acta - Bioenergetics | 2009 | 684 |
| 21 | Current concepts in neuroanatomical tracing | Progress in Neurobiology | 2000 | 644 |
| 22 | The versatility and adaptation of bacteria from the genus Stenotrophomonas | Nature Reviews Microbiology | 2009 | 641 |
| 23 | Paired‐pulse depression of monosynaptic GABA‐mediated inhibitory postsynaptic responses in rat hippocampus. | Journal of Physiology | 1990 | 637 |
| 24 | Transport of lactate and other monocarboxylates across mammalian plasma membranes | American Journal of Physiology - Cell Physiology | 1993 | 636 |
| 25 | Actin stress fibres | Journal of Cell Science | 2007 | 616 |
| 26 | Wound repair at a glance | Journal of Cell Science | 2009 | 613 |
| 27 | Identification of Monocarboxylate Transporter 8 as a Specific Thyroid Hormone Transporter | Journal of Biological Chemistry | 2003 | 602 |
| 28 | Central Oxytocin Administration Reduces Stress-Induced Corticosterone Release and Anxiety Behavior in Rats1 | Endocrinology | 1997 | 590 |
| 29 | IL-10-Secreting Regulatory T Cells Do Not Express Foxp3 but Have Comparable Regulatory Function to Naturally Occurring CD4+CD25+ Regulatory T Cells | Journal of Immunology | 2004 | 583 |
| 30 | GABAB autoreceptors regulate the induction of LTP | Nature | 1991 | 569 |
| 31 | CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression | EMBO Journal | 2000 | 566 |
| 32 | Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase | Biochemical Journal | 1993 | 552 |
| 33 | Protection by Cyclosporin A of Ischemia/Reperfusion-Induced Damage in Isolated Rat Hearts | Journal of Molecular and Cellular Cardiology | 1993 | 549 |
| 34 | Mechanisms, regulation and consequences of protein SUMOylation | Biochemical Journal | 2010 | 549 |
| 35 | The potential diagram for oxygen at pH 7 | Biochemical Journal | 1988 | 544 |
| 36 | IS CR Elements: Novel Gene-Capturing Systems of the 21st Century? | Microbiology and Molecular Biology Reviews | 2006 | 529 |
| 37 | Oxidative Stress, Thiol Reagents, and Membrane Potential Modulate the Mitochondrial Permeability Transition by Affecting Nucleotide Binding to the Adenine Nucleotide Translocase | Journal of Biological Chemistry | 1997 | 525 |
| 38 | Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: Implications for the possible role of dietary fibre in the prevention of large-bowel cancer | International Journal of Cancer | 1993 | 510 |
| 39 | Parallels between tissue repair and embryo morphogenesis | Development (Cambridge) | 2004 | 501 |
| 40 | Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation | Nature Neuroscience | 2006 | 464 |
| 41 | The Adenine Nucleotide Translocase: A Central Component of the Mitochondrial Permeability Transition Pore and Key Player in Cell Death | Current Medicinal Chemistry | 2003 | 454 |
| 42 | Temporally distinct pre- and post-synaptic mechanisms maintain long-term potentiation | Nature | 1989 | 452 |
| 43 | The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants | Genome Biology | 2008 | 452 |
| 44 | Cerebellar cortical organization: a one-map hypothesis | Nature Reviews Neuroscience | 2009 | 448 |
| 45 | Enzymic mechanisms of superoxide production | Biochimica Et Biophysica Acta - Bioenergetics | 1991 | 430 |
| 46 | A working heart-brainstem preparation of the mouse | Journal of Neuroscience Methods | 1996 | 429 |
| 47 | Calcium, mitochondria and reperfusion injury: a pore way to die | Biochemical Society Transactions | 2006 | 422 |
| 48 | Memories of NMDA receptors and LTP | Trends in Neurosciences | 1995 | 421 |
| 49 | Sorting Nexin-1 Mediates Tubular Endosome-to-TGN Transport through Coincidence Sensing of High- Curvature Membranes and 3-Phosphoinositides | Current Biology | 2004 | 414 |
| 50 | The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation | Biochemical Journal | 1999 | 404 |
