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exaly
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Department of Biochemistry
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top-articles
Department of Biochemistry
1.0K
(top 0.1%)
papers
46.6K
(top 0.1%)
citations
102
(top 0.1%)
h
-index
162
(top 0.1%)
g
-index
1.3K
all documents
51.0K
doc citations
3.8K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics
Nature
2010
1,274
2
Reconstitution of Membrane Proteins in Phospholipid Bilayer Nanodiscs
Methods in Enzymology
2009
726
3
Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4
Blood
2011
708
4
Design and synthesis of multi-haem proteins
Nature
1994
592
5
Brd4 Coactivates Transcriptional Activation of NF-κB via Specific Binding to Acetylated RelA
Molecular and Cellular Biology
2009
505
6
Glycoprotein biosynthesis in yeast
FASEB Journal
1993
496
7
Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease
Nature
2019
493
8
Polyphosphate modulates blood coagulation and fibrinolysis
Proceedings of the National Academy of Sciences of the United States of America
2006
487
9
Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma
Immunity
2016
458
10
New developments in RiPP discovery, enzymology and engineering
Natural Product Reports
2021
412
11
Nanodiscs for structural and functional studies of membrane proteins
Nature Structural and Molecular Biology
2016
378
12
A DNAzyme-Gold Nanoparticle Probe for Uranyl Ion in Living Cells
Journal of the American Chemical Society
2013
376
13
Amphotericin forms an extramembranous and fungicidal sterol sponge
Nature Chemical Biology
2014
359
14
T‐cell receptor binding affinities and kinetics: impact on T‐cell activity and specificity
Immunology
2009
313
15
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants
Science
2021
309
16
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
Science
2021
304
17
How it all starts: Initiation of the clotting cascade
Critical Reviews in Biochemistry and Molecular Biology
2015
303
18
Posttranslational modifications of NF-κB: Another layer of regulation for NF-κB signaling pathway
Cellular Signalling
2010
285
19
Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB
Nature
2015
278
20
Structure and Mechanism of the Lantibiotic Cyclase Involved in Nisin Biosynthesis
Science
2006
275
21
Polyphosphate exerts differential effects on blood clotting, depending on polymer size
Blood
2010
261
22
Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria
Proceedings of the National Academy of Sciences of the United States of America
2010
256
23
Topology and reorganization of a human TFIID–promoter complex
Nature
1996
246
24
A highly selective lead sensor based on a classic lead DNAzyme
Chemical Communications
2010
246
25
Understanding the Role of the Essential Asp251 in Cytochrome P450cam Using Site-Directed Mutagenesis, Crystallography, and Kinetic Solvent Isotope Effect
Biochemistry
1998
243
26
New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products
Cell Chemical Biology
2016
241
27
Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target
Frontiers in Physiology
2017
238
28
Structure of co-crystals of tropomyosin and troponin
Nature
1987
236
29
T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex
Immunity
2011
229
30
Rational design of a structural and functional nitric oxide reductase
Nature
2009
218
31
How a Single T Cell Receptor Recognizes Both Self and Foreign MHC
Cell
2007
217
32
Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA
Oncogene
2014
215
33
Transcription activator‐like effector nucleases (TALENs): A highly efficient and versatile tool for genome editing
Biotechnology and Bioengineering
2013
210
34
Polyphosphate is a cofactor for the activation of factor XI by thrombin
Blood
2011
209
35
Optogenetic control of intracellular signaling pathways
Trends in Biotechnology
2015
208
36
Activation and characterization of a cryptic polycyclic tetramate macrolactam biosynthetic gene cluster
Nature Communications
2013
206
37
Molecular dynamics simulations of membrane channels and transporters
Current Opinion in Structural Biology
2009
201
38
High-performance solvent suppression for proton detected solid-state NMR
Journal of Magnetic Resonance
2008
199
39
Negative regulation of NF-κB action by Set9-mediated lysine methylation of the RelA subunit
EMBO Journal
2009
197
40
Optical Control of Metal Ion Probes in Cells and Zebrafish Using Highly Selective DNAzymes Conjugated to Upconversion Nanoparticles
Journal of the American Chemical Society
2018
196
41
Lecithin-cholesterol acyltransferase in the metabolism of high-density lipoproteins
Lipids and Lipid Metabolism
1991
194
42
X-ray structures define human P2X3 receptor gating cycle and antagonist action
Nature
2016
191
43
The immune system and inflammation in breast cancer
Molecular and Cellular Endocrinology
2014
189
44
Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein
Nature
2017
189
45
Factor XII inhibition reduces thrombus formation in a primate thrombosis model
Blood
2014
187
46
Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport
Nature
2019
187
47
Discovery of Unique Lanthionine Synthetases Reveals New Mechanistic and Evolutionary Insights
PLoS Biology
2010
186
48
Nanodiscs separate chemoreceptor oligomeric states and reveal their signaling properties
Proceedings of the National Academy of Sciences of the United States of America
2006
181
49
Photocaged DNAzymes as a General Method for Sensing Metal Ions in Living Cells
Angewandte Chemie - International Edition
2014
181
50
Evolution of lanthipeptide synthetases
Proceedings of the National Academy of Sciences of the United States of America
2012
178
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