# | Title | Journal | Year | Citations |
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1 | Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2 | Nature Biotechnology | 2019 | 11,167 |
2 | Patient-derived tumour xenografts as models for oncology drug development | Nature Reviews Clinical Oncology | 2012 | 1,091 |
3 | Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program | Nature | 2021 | 1,069 |
4 | Mechanisms of Resistance to Crizotinib in Patients with ALK Gene Rearranged Non–Small Cell Lung Cancer | Clinical Cancer Research | 2012 | 1,018 |
5 | Tumor Mutational Burden and Efficacy of Nivolumab Monotherapy and in Combination with Ipilimumab in Small-Cell Lung Cancer | Cancer Cell | 2018 | 725 |
6 | A Prospective, Multi-institutional, Pathologist-Based Assessment of 4 Immunohistochemistry Assays for PD-L1 Expression in Non–Small Cell Lung Cancer | JAMA Oncology | 2017 | 658 |
7 | Fructose and sugar: A major mediator of non-alcoholic fatty liver disease | Journal of Hepatology | 2018 | 617 |
8 | Rivaroxaban in Peripheral Artery Disease after Revascularization | New England Journal of Medicine | 2020 | 566 |
9 | Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non–Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors | Advances in Anatomic Pathology | 2017 | 530 |
10 | Liquid Biopsy for Advanced Non-Small Cell Lung Cancer (NSCLC): A Statement Paper from the IASLC | Journal of Thoracic Oncology | 2018 | 515 |
11 | An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia | Mucosal Immunology | 2014 | 404 |
12 | Obesity and Type 2 Diabetes: What Can Be Unified and What Needs to Be Individualized? | Journal of Clinical Endocrinology and Metabolism | 2011 | 384 |
13 | Inherited causes of clonal haematopoiesis in 97,691 whole genomes | Nature | 2020 | 376 |
14 | Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing | Cell | 2020 | 371 |
15 | Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers | Clinical Cancer Research | 2018 | 366 |
16 | Effects of Intensive BP Control in CKD | Journal of the American Society of Nephrology: JASN | 2017 | 364 |
17 | Biology's response to dieting: the impetus for weight regain | American Journal of Physiology - Regulatory Integrative and Comparative Physiology | 2011 | 348 |
18 | The trans-ancestral genomic architecture of glycemic traits | Nature Genetics | 2021 | 341 |
19 | Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2 | Nature Medicine | 2011 | 318 |
20 | Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide | Breast Cancer Research | 2014 | 315 |
21 | Inflammation: a key regulator of hematopoietic stem cell fate in health and disease | Blood | 2017 | 286 |
22 | Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults | Hypertension | 2018 | 280 |
23 | Relation between door-to-balloon times and mortality after primary percutaneous coronary intervention over time: a retrospective study | Lancet, The | 2015 | 279 |
24 | The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer | Oncogene | 2012 | 276 |
25 | Oncogene status predicts patterns of metastatic spread in treatment‐naive nonsmall cell lung cancer | Cancer | 2012 | 247 |
26 | RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK–positive lung cancer | Nature Medicine | 2015 | 245 |
27 | Temporal trends in marijuana attitudes, availability and use in Colorado compared to non-medical marijuana states: 2003–11 | Drug and Alcohol Dependence | 2014 | 243 |
28 | Obesity and Type 2 Diabetes: What Can Be Unified and What Needs to Be Individualized? | Diabetes Care | 2011 | 214 |
29 | A randomized pilot study comparing zero‐calorie alternate‐day fasting to daily caloric restriction in adults with obesity | Obesity | 2016 | 214 |
30 | DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination | Gynecologic Oncology | 2012 | 213 |
31 | Endothelial Function Is Impaired across the Stages of the Menopause Transition in Healthy Women | Journal of Clinical Endocrinology and Metabolism | 2012 | 211 |
32 | A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop | Oncogenesis | 2013 | 211 |
33 | Inflammatory Bowel Diseases Phenotype, C. difficile and NOD2 Genotype Are Associated with Shifts in Human Ileum Associated Microbial Composition | PLoS ONE | 2012 | 207 |
34 | The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD | Nature Communications | 2018 | 205 |
35 | Male breast cancer: a disease distinct from female breast cancer | Breast Cancer Research and Treatment | 2019 | 205 |
36 | TNF-α–driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging | Blood | 2019 | 199 |
37 | Trends in U.S. Cardiovascular Care | Journal of the American College of Cardiology | 2017 | 198 |
38 | LAG-3 Protein Expression in Non–Small Cell Lung Cancer and Its Relationship with PD-1/PD-L1 and Tumor-Infiltrating Lymphocytes | Journal of Thoracic Oncology | 2017 | 192 |
39 | Effectiveness of Intermittent Fasting and Time-Restricted Feeding Compared to Continuous Energy Restriction for Weight Loss | Nutrients | 2019 | 191 |
40 | Myosteatosis in the Context of Skeletal Muscle Function Deficit: An Interdisciplinary Workshop at the National Institute on Aging | Frontiers in Physiology | 2020 | 190 |
41 | Patient-derived xenograft (PDX) models in basic and translational breast cancer research | Cancer and Metastasis Reviews | 2016 | 189 |
42 | Multiple Molecular Subtypes of Triple-Negative Breast Cancer Critically Rely on Androgen Receptor and Respond to Enzalutamide In Vivo | Molecular Cancer Therapeutics | 2015 | 184 |
43 | Comparison of Fecal Microbiota in Children with Autism Spectrum Disorders and Neurotypical Siblings in the Simons Simplex Collection | PLoS ONE | 2015 | 173 |
44 | TIM-3, a promising target for cancer immunotherapy | OncoTargets and Therapy | 2018 | 172 |
45 | Old and new adjuvants | Current Opinion in Immunology | 2017 | 170 |
46 | Lymphocyte‐activation gene‐3, an important immune checkpoint in cancer | Cancer Science | 2016 | 168 |
47 | Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection | Mucosal Immunology | 2016 | 167 |
48 | Microbiota-derived butyrate dynamically regulates intestinal homeostasis through regulation of actin-associated protein synaptopodin | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 165 |
49 | Plasma-Based Circulating MicroRNA Biomarkers for Parkinson's Disease | Journal of Parkinson's Disease | 2012 | 161 |
50 | Rationale, Design and Methodology of the Computerized Registry of Patients with Venous Thromboembolism (RIETE) | Thrombosis and Haemostasis | 2018 | 160 |