| # | Title | Journal | Year | Citations |
|---|
| 1 | Inspiratory Muscle Unloading by Neurally Adjusted Ventilatory Assist During Maximal Inspiratory Efforts in Healthy Subjects | Chest | 2007 | 729 |
| 2 | Clinical Risk Score for Persistent Postconcussion Symptoms Among Children With Acute Concussion in the ED | JAMA - Journal of the American Medical Association | 2016 | 628 |
| 3 | Parental genomic imprinting of the human IGF2 gene | Nature Genetics | 1993 | 425 |
| 4 | European Society for Paediatric Endocrinology Consensus Guidelines on Screening, Diagnosis, and Management of Congenital Hypothyroidism | Journal of Clinical Endocrinology and Metabolism | 2014 | 403 |
| 5 | Social networks predict gut microbiome composition in wild baboons | ELife | 2015 | 403 |
| 6 | Diagnostic accuracy of serological assays in pediatric inflammatory bowel disease | Gastroenterology | 1998 | 383 |
| 7 | Neutrophils: Cinderella of innate immune system | International Immunopharmacology | 2010 | 343 |
| 8 | Epidemiology of Sepsis and Multiple Organ Dysfunction Syndrome in Children | Chest | 1996 | 339 |
| 9 | Hypertension Canada’s 2020 Comprehensive Guidelines for the Prevention, Diagnosis, Risk Assessment, and Treatment of Hypertension in Adults and Children | Canadian Journal of Cardiology | 2020 | 324 |
| 10 | Diversity and Function of Mutations in P450 Oxidoreductase in Patients with Antley-Bixler Syndrome and Disordered Steroidogenesis | American Journal of Human Genetics | 2005 | 321 |
| 11 | The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis | Nature Medicine | 2008 | 317 |
| 12 | Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia | Genome Biology | 2013 | 314 |
| 13 | Stroke in children | Neurology | 2000 | 312 |
| 14 | 6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity. | Gut | 1996 | 301 |
| 15 | Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study | Blood | 2011 | 296 |
| 16 | Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host | Nature | 2018 | 296 |
| 17 | Acute kidney injury is an independent risk factor for pediatric intensive care unit mortality, longer length of stay and prolonged mechanical ventilation in critically ill children: a two-center retrospective cohort study | Critical Care | 2011 | 294 |
| 18 | The Use of Alternative Medicine by Children | Pediatrics | 1994 | 291 |
| 19 | Preemptive Use of High-Dose Fluticasone for Virus-Induced Wheezing in Young Children | New England Journal of Medicine | 2009 | 283 |
| 20 | ESPGHAN‐NASPGHAN Guidelines for the Evaluation and Treatment of Gastrointestinal and Nutritional Complications in Children With Esophageal Atresia‐Tracheoesophageal Fistula | Journal of Pediatric Gastroenterology and Nutrition | 2016 | 277 |
| 21 | Hypertension Canada's 2017 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults | Canadian Journal of Cardiology | 2017 | 269 |
| 22 | Alu sequences in the coding regions of mRNA: a source of protein variability | Trends in Genetics | 1994 | 267 |
| 23 | Allele-Specific Chromatin Remodeling in the ZPBP2/GSDMB/ORMDL3 Locus Associated with the Risk of Asthma and Autoimmune Disease | American Journal of Human Genetics | 2009 | 262 |
| 24 | Imbalances in Dietary Consumption of Fatty Acids, Vegetables, and Fruits Are Associated With Risk for Crohn's Disease in Children | American Journal of Gastroenterology | 2007 | 259 |
| 25 | The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies | Nature Genetics | 2017 | 251 |
| 26 | Association Between Early Participation in Physical Activity Following Acute Concussion and Persistent Postconcussive Symptoms in Children and Adolescents | JAMA - Journal of the American Medical Association | 2016 | 250 |
| 27 | The use of alternative medicine by children | Pediatrics | 1994 | 250 |
| 28 | Branched-chain amino acid metabolism: from rare Mendelian diseases to more common disorders | Human Molecular Genetics | 2014 | 234 |
| 29 | Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study | Journal of Allergy and Clinical Immunology | 2018 | 233 |
| 30 | A survey of genetic and epigenetic variation affecting human gene expression | Physiological Genomics | 2004 | 228 |
| 31 | International workshop on immune tolerance induction: consensus recommendations | Haemophilia | 2007 | 228 |
| 32 | Direct Measure of the De Novo Mutation Rate in Autism and Schizophrenia Cohorts | American Journal of Human Genetics | 2010 | 222 |
| 33 | Risk factors of acute renal failure in critically ill children: A prospective descriptive epidemiological study* | Pediatric Critical Care Medicine | 2007 | 217 |
| 34 | Biliary Atresia: The Canadian Experience | Journal of Pediatrics | 2007 | 215 |
| 35 | Do you see what I see? Weight status misperception and exposure to obesity among children and adolescents | International Journal of Obesity | 2008 | 214 |
| 36 | Epidemiology and Outcomes of Arterial Ischemic Stroke in Children: The Canadian Pediatric Ischemic Stroke Registry | Pediatric Neurology | 2017 | 213 |
| 37 | Immune reconstitution and survival of 100 SCID patients post–hematopoietic cell transplant: a PIDTC natural history study | Blood | 2017 | 212 |
| 38 | Wireless capsule endoscopy for obscure small-bowel disorders: Final results of the first pediatric controlled trial | Clinical Gastroenterology and Hepatology | 2005 | 205 |
| 39 | Tracing the origins of “fetal origins” of adult diseases: Programming by oxidative stress? | Medical Hypotheses | 2006 | 204 |
| 40 | Nitric oxide for respiratory failure in infants born at or near term | The Cochrane Library | 2017 | 204 |
| 41 | Timing and predictors of death in pediatric patients with multiple organ system failure | Critical Care Medicine | 1994 | 200 |
| 42 | Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis | Lancet Haematology,the | 2016 | 197 |
| 43 | Is the Incidence of Congenital Hypothyroidism Really Increasing? A 20-Year Retrospective Population-Based Study in Québec | Journal of Clinical Endocrinology and Metabolism | 2011 | 196 |
| 44 | Determinants of developmental outcomes in a very preterm Canadian cohort | Archives of Disease in Childhood: Fetal and Neonatal Edition | 2017 | 196 |
| 45 | Self-management teaching programs and morbidity of pediatric asthma: A meta-analysis | Journal of Allergy and Clinical Immunology | 1995 | 195 |
| 46 | European Society for Paediatric Endocrinology Consensus Guidelines on Screening, Diagnosis, and Management of Congenital Hypothyroidism | Hormone Research in Paediatrics | 2014 | 193 |
| 47 | Clinical Validity of Genes for Heritable Thoracic Aortic Aneurysm and Dissection | Journal of the American College of Cardiology | 2018 | 190 |
| 48 | The mutation spectrum in RECQL4 diseases | European Journal of Human Genetics | 2009 | 189 |
| 49 | Haploinsufficiency of SF3B4, a Component of the Pre-mRNA Spliceosomal Complex, Causes Nager Syndrome | American Journal of Human Genetics | 2012 | 188 |
| 50 | Risk of Childhood Leukemia Associated with Exposure to Pesticides and with Gene Polymorphisms | Epidemiology | 1999 | 187 |
