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Top Articles

#TitleJournalYearCitations
1Magneto-aerotactic bacteria deliver drug-containing nanoliposomes to tumour hypoxic regionsNature Nanotechnology2016810
2The molecular basis of retinal ganglion cell death in glaucomaProgress in Retinal and Eye Research2012755
3Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translationProceedings of the National Academy of Sciences of the United States of America2008716
4RAS/ERK Signaling Promotes Site-specific Ribosomal Protein S6 Phosphorylation via RSK and Stimulates Cap-dependent TranslationJournal of Biological Chemistry2007627
5mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 SignalingMolecular and Cellular Biology2010365
6Comprehensive Characterization of Extracellular Herpes Simplex Virus Type 1 VirionsJournal of Virology2008332
7The succinate receptor GPR91 in neurons has a major role in retinal angiogenesisNature Medicine2008317
8Oncogenic MAPK Signaling Stimulates mTORC1 Activity by Promoting RSK-Mediated Raptor PhosphorylationCurrent Biology2008291
9mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptideEMBO Journal2010290
10TrkB Gene Transfer Protects Retinal Ganglion Cells from Axotomy-Induced DeathIn VivoJournal of Neuroscience2002245
11Resolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammationProceedings of the National Academy of Sciences of the United States of America2012238
12Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophreniaHuman Genetics2011237
13Inhibition of RAS function through targeting an allosteric regulatory siteNature Chemical Biology2017237
14Plasma membrane domain organization regulates EGFR signaling in tumor cellsJournal of Cell Biology2007231
15Direct Measure of the De Novo Mutation Rate in Autism and Schizophrenia CohortsAmerican Journal of Human Genetics2010222
16C-reactive protein and inflammation: conformational changes affect functionBiological Chemistry2015222
17The Phagosomal Proteome in Interferon-γ-Activated MacrophagesImmunity2009206
18Caveolin-1 Is a Negative Regulator of Caveolae-mediated Endocytosis to the Endoplasmic ReticulumJournal of Biological Chemistry2002205
19In Situ Localization of P-glycoprotein (ABCB1) in Human and Rat BrainJournal of Histochemistry and Cytochemistry2006199
20Galectin Binding to Mgat5-Modified N-Glycans Regulates Fibronectin Matrix Remodeling in Tumor CellsMolecular and Cellular Biology2006185
21Distinct caveolae-mediated endocytic pathways target the Golgi apparatus and the endoplasmic reticulumJournal of Cell Science2003184
22Neural transplants in patients with Huntington's disease undergo disease-like neuronal degenerationProceedings of the National Academy of Sciences of the United States of America2009183
23The RSK factors of activating the Ras/MAPK signaling cascadeFrontiers in Bioscience - Landmark2008183
24Functional expression and localization of P-glycoprotein at the blood brain barrierMicroscopy Research and Technique2002178
25Calcium Regulates the Association between Mitochondria and a Smooth Subdomain of the Endoplasmic ReticulumJournal of Cell Biology2000160
26Regulation of mTOR Complex 1 (mTORC1) by Raptor Ser863 and Multisite PhosphorylationJournal of Biological Chemistry2010158
27EPCR expression marks UM171-expanded CD34+ cord blood stem cellsBlood2017158
28Biogenesis of Multilamellar Bodies via AutophagyMolecular Biology of the Cell2000157
29The neurobiology of depression—revisiting the serotonin hypothesis. I. Cellular and molecular mechanismsPhilosophical Transactions of the Royal Society B: Biological Sciences2012155
30C9orf72 repeat expansions are a rare genetic cause of parkinsonismBrain2013143
31Herpes Simplex Virus Type 1 Capsids Transit by the trans -Golgi Network, Where Viral Glycoproteins Accumulate Independently of Capsid EgressJournal of Virology2005142
32Synergistic action of brain-derived neurotrophic factor and lens injury promotes retinal ganglion cell survival, but leads to optic nerve dystrophy in vivoBrain2006141
33Localization and role of NPC1L1 in cholesterol absorption in human intestineJournal of Lipid Research2006141
34De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsyAnnals of Neurology2009141
35Controlling Gene Expression through RNA Regulons: The Role of the Eukaryotic Translation Initiation Factor eIF4ECell Cycle2007136
36Rab11 regulates cell–cell communication during collective cell movementsNature Cell Biology2013136
37Estrogen Signals Through Peroxisome Proliferator-Activated Receptor−γ Coactivator 1α to Reduce Oxidative Damage Associated With Diet-Induced Fatty Liver DiseaseGastroenterology2017132
38Disruption of AP1S1, Causing a Novel Neurocutaneous Syndrome, Perturbs Development of the Skin and Spinal CordPLoS Genetics2008131
39Aging of the subventricular zone neural stem cell niche: evidence for quiescence-associated changes between early and mid-adulthoodNeuroscience2011131
40Aspirin-Triggered Lipoxins Override the Apoptosis-Delaying Action of Serum Amyloid A in Human Neutrophils: A Novel Mechanism for Resolution of InflammationJournal of Immunology2007128
41The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer ProgressionCell Reports2018127
42Endogenous neural stem cell responses to stroke and spinal cord injuryGlia2015126
43α/β-Hydrolase Domain-6-Accessible Monoacylglycerol Controls Glucose-Stimulated Insulin SecretionCell Metabolism2014125
44Transgenic BDNF induces nerve fiber regrowth into the auditory epithelium in deaf cochleaeExperimental Neurology2010121
45The Oncogene eIF4E Reprograms the Nuclear Pore Complex to Promote mRNA Export and Oncogenic TransformationCell Reports2012120
46Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?Leukemia and Lymphoma2010118
47Regulation of global and specific mRNA translation by the mTOR signaling pathwayTranslation2015117
48Fibroblast growth factor-2 gene delivery stimulates axon growth by adult retinal ganglion cells after acute optic nerve injuryMolecular and Cellular Neurosciences2003111
49Cytokinesis, ploidy and aneuploidyJournal of Pathology2012107
50Mammalian Target of Rapamycin Signaling Is a Key Regulator of the Transit-Amplifying Progenitor Pool in the Adult and Aging ForebrainJournal of Neuroscience2012105