# | Title | Journal | Year | Citations |
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1 | The BCL-2 protein family: opposing activities that mediate cell death | Nature Reviews Molecular Cell Biology | 2008 | 3,898 |
2 | Parkin is recruited selectively to impaired mitochondria and promotes their autophagy | Journal of Cell Biology | 2008 | 3,315 |
3 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
4 | Mitochondrial Fission, Fusion, and Stress | Science | 2012 | 2,645 |
5 | Mechanisms of mitophagy | Nature Reviews Molecular Cell Biology | 2011 | 2,638 |
6 | PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin | PLoS Biology | 2010 | 2,299 |
7 | Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines | Cancer Cell | 2006 | 2,056 |
8 | The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy | Nature | 2015 | 1,969 |
9 | Movement of Bax from the Cytosol to Mitochondria during Apoptosis | Journal of Cell Biology | 1997 | 1,667 |
10 | The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis | Developmental Cell | 2001 | 1,564 |
11 | In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors | Science | 1992 | 1,529 |
12 | The Role of Mitochondria in Apoptosis | Annual Review of Genetics | 2009 | 1,503 |
13 | Phase II Trial of Single-Agent Bevacizumab Followed by Bevacizumab Plus Irinotecan at Tumor Progression in Recurrent Glioblastoma | Journal of Clinical Oncology | 2009 | 1,413 |
14 | von Hippel-Lindau disease | Lancet, The | 2003 | 1,322 |
15 | Convection-enhanced delivery of macromolecules in the brain. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 1,278 |
16 | Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance | Current Biology | 2018 | 1,262 |
17 | Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin | Journal of Cell Biology | 2010 | 1,161 |
18 | Cytosol-to-membrane redistribution of Bax and Bcl-XL during apoptosis | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 1,086 |
19 | Mitochondrial dynamics and apoptosis | Genes and Development | 2008 | 1,080 |
20 | Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL | Journal of Cell Biology | 2010 | 1,078 |
21 | Structure of Bax | Cell | 2000 | 1,008 |
22 | Roles of the Mammalian Mitochondrial Fission and Fusion Mediators Fis1, Drp1, and Opa1 in Apoptosis | Molecular Biology of the Cell | 2004 | 920 |
23 | Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells | Journal of Cell Biology | 2010 | 919 |
24 | Parkin and PINK1 mitigate STING-induced inflammation | Nature | 2018 | 905 |
25 | Petrosal Sinus Sampling with and without Corticotropin-Releasing Hormone for the Differential Diagnosis of Cushing's Syndrome | New England Journal of Medicine | 1991 | 795 |
26 | Mitochondrial fission in apoptosis | Nature Reviews Molecular Cell Biology | 2005 | 681 |
27 | Conformation of the Bax C-terminus regulates subcellular location and cell death | EMBO Journal | 1999 | 667 |
28 | Pathophysiology of syringomyelia associated with Chiari I malformation of the cerebellar tonsils | Journal of Neurosurgery | 1994 | 650 |
29 | SLP-2 is required for stress-induced mitochondrial hyperfusion | EMBO Journal | 2009 | 639 |
30 | Expression of Hypoxia-Inducible Cell-Surface Transmembrane Carbonic Anhydrases in Human Cancer | American Journal of Pathology | 2001 | 606 |
31 | Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons | EMBO Journal | 2006 | 603 |
32 | Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 554 |
33 | Nonionic Detergents Induce Dimerization among Members of the Bcl-2 Family | Journal of Biological Chemistry | 1997 | 541 |
34 | Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin | Developmental Cell | 2012 | 523 |
35 | Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors | Nature Medicine | 1997 | 517 |
36 | Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol | Cell | 2011 | 512 |
37 | Neurofibromatosis type 2 | Lancet, The | 2009 | 508 |
38 | PINK1 is degraded through the N-end rule pathway | Autophagy | 2013 | 507 |
39 | JNK-Mediated BIM Phosphorylation Potentiates BAX-Dependent Apoptosis | Neuron | 2003 | 479 |
40 | Bax in Murine Thymus Is a Soluble Monomeric Protein That Displays Differential Detergent-induced Conformations | Journal of Biological Chemistry | 1998 | 465 |
41 | PINK1- and Parkin-mediated mitophagy at a glance | Journal of Cell Science | 2012 | 465 |
42 | Drp-1-Dependent Division of the Mitochondrial Network Blocks Intraorganellar Ca2+ Waves and Protects against Ca2+-Mediated Apoptosis | Molecular Cell | 2004 | 440 |
43 | The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division | Journal of Cell Biology | 2007 | 420 |
44 | Bax and Bak Coalesce into Novel Mitochondria-Associated Clusters during Apoptosis | Journal of Cell Biology | 2001 | 418 |
45 | Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms. | Journal of Clinical Investigation | 1993 | 417 |
46 | Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI | ELife | 2017 | 403 |
47 | Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis | Journal of Cell Biology | 2004 | 393 |
48 | The natural history of hemangioblastomas of the central nervous system in patients with von Hippel—Lindau disease | Journal of Neurosurgery | 2003 | 392 |
49 | Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization | EMBO Journal | 2003 | 383 |
50 | Mitochondrial fission facilitates the selective mitophagy of protein aggregates | Journal of Cell Biology | 2017 | 377 |