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Top Articles

#TitleJournalYearCitations
1p53 Regulates Mitochondrial RespirationScience20061,450
2Prognostic Value of Coronary Vascular Endothelial DysfunctionCirculation20021,293
3Oxygen radicals and signalingCurrent Opinion in Cell Biology19981,047
4Enhanced Detection of Ischemic but Viable Myocardium by the Reinjection of Thallium after Stress-Redistribution ImagingNew England Journal of Medicine1990763
5Potential role of human cytomegalovirus and p53 interaction in coronary restenosisScience1994757
6Current diagnostic techniques of assessing myocardial viability in patients with hibernating and stunned myocardium.Circulation1993652
7Ras Proteins Induce Senescence by Altering the Intracellular Levels of Reactive Oxygen SpeciesJournal of Biological Chemistry1999585
8Coronary artery imaging with intravascular high-frequency ultrasound.Circulation1990577
9Circadian Variation in Vascular Tone and Its Relation to α-Sympathetic Vasoconstrictor ActivityNew England Journal of Medicine1991572
10Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs.Circulation1994569
11Identification of viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction. Comparison of thallium scintigraphy with reinjection and PET imaging with 18F-fluorodeoxyglucose.Circulation1991568
12Reactive oxygen species are downstream mediators of p53-dependent apoptosis.Proceedings of the National Academy of Sciences of the United States of America1996536
13“Microvascular angina” as a cause of chest pain with angiographically normal coronary arteriesAmerican Journal of Cardiology1988532
14Acute vascular effects of estrogen in postmenopausal women.Circulation1994525
15The Mammalian Target of Rapamycin (mTOR) Pathway Regulates Mitochondrial Oxygen Consumption and Oxidative CapacityJournal of Biological Chemistry2006524
16Effects of physiological levels of estrogen on coronary vasomotor function in postmenopausal women.Circulation1994502
17Structural features of the athlete heart as defined by echocardiographyJournal of the American College of Cardiology1986491
18Imipramine in Patients with Chest Pain Despite Normal Coronary AngiogramsNew England Journal of Medicine1994477
19Serial long-term assessment of the natural history of asymptomatic patients with chronic aortic regurgitation and normal left ventricular systolic function.Circulation1991446
20Noninvasive assessment of left ventricular diastolic function: Comparative analysis of Doppler echocardiographic and radionuclide angiographic techniquesJournal of the American College of Cardiology1986440
21Endothelial function in health and disease: new insights into the genesis of cardiovascular diseaseAmerican Journal of Medicine1998345
22Interplay among BRCA1, SIRT1, and Survivin during BRCA1-Associated TumorigenesisMolecular Cell2008334
23Pathophysiological dilemma of syndrome X.Circulation1992333
24Velocity of contraction as a determinant of myocardial oxygen consumptionAmerican Journal of Physiology1965331
25The role of nitric oxide in endothelium-dependent vasodilation of hypercholesterolemic patients.Circulation1993326
26Impaired Endothelium-Dependent Vasodilation in Patients With Essential HypertensionCirculation1995295
27Occurrence and significance of progressive left ventricular wall thinning and relative cavity dilatation in hypertrophic cardiomyopathyAmerican Journal of Cardiology1987294
28Inhibition of Phosphatidylinositol 3-Kinase Enhances Mitogenic Actions of Insulin in Endothelial CellsJournal of Biological Chemistry2002285
29Insulin Stimulates Both Endothelin and Nitric Oxide Activity in the Human ForearmCirculation1999279
30Predisposition to Atherosclerosis by InfectionsCirculation2002279
31Role of nitric oxide in cardiovascular disease: focus on the endotheliumClinical Chemistry1998276
32Effects of total pathogen burden on coronary artery disease risk and C-reactive protein levelsAmerican Journal of Cardiology2000272
33Contribution of endothelium-derived nitric oxide to exercise-induced vasodilation.Circulation1994269
34Myocardial ischemia detected by thallium scintigraphy is frequently related to cardiac arrest and syncope in young patients with hypertrophic cardiomyopathyJournal of the American College of Cardiology1993267
35Efficient gene transfer into myocardium by direct injection of adenovirus vectors.Circulation Research1993261
36Exercise-induced left ventricular dysfunction in symptomatic and asymptomatic patients with aortic regurgitation: Assessment with radionuclide cineangiographyAmerican Journal of Cardiology1978257
37Contribution of Nitric Oxide to Metabolic Coronary Vasodilation in the Human HeartCirculation1995249
38Increased Activity of Endogenous Endothelin in Patients With Type II Diabetes MellitusCirculation2002248
39Myocardial viability in patients with chronic coronary artery disease. Comparison of 99mTc-sestamibi with thallium reinjection and [18F]fluorodeoxyglucose.Circulation1994247
40Insertion-Deletion Polymorphism of the ACE Gene Modulates Reversibility of Endothelial Dysfunction With ACE InhibitionCirculation2000245
41The Overall Pattern of Cardiac Contraction Depends on a Spatial Gradient of Myosin Regulatory Light Chain PhosphorylationCell2001245
42Role of Endothelin in the Increased Vascular Tone of Patients With Essential HypertensionHypertension1999243
43Effect of antihypertensive treatment on endothelium-dependent vascular relaxation in patients with essential hypertensionJournal of the American College of Cardiology1993235
44Endothelial dysfunction in patients with chest pain and normal coronary arteries.Circulation1992222
45Abnormal cardiac sensitivity in patients with chest pain and normal coronary arteriesJournal of the American College of Cardiology1990216
46Insulin Receptor Substrate-1 and Phosphoinositide-Dependent Kinase-1 Are Required for Insulin-Stimulated Production of Nitric Oxide in Endothelial CellsMolecular Endocrinology2002203
47Protein Kinase C-ζ Phosphorylates Insulin Receptor Substrate-1 and Impairs Its Ability to Activate Phosphatidylinositol 3-Kinase in Response to InsulinJournal of Biological Chemistry2001201
48Xanthine Oxidase Inhibition With Oxypurinol Improves Endothelial Vasodilator Function in Hypercholesterolemic but Not in Hypertensive PatientsHypertension1997197
49Effects of Chronic Systemic Administration of Basic Fibroblast Growth Factor on Collateral Development in the Canine HeartCirculation1995192
50Missense mutations in the beta-myosin heavy-chain gene cause central core disease in hypertrophic cardiomyopathy.Proceedings of the National Academy of Sciences of the United States of America1993187