| # | Title | Journal | Year | Citations |
|---|
| 1 | Cancer risk in mutation carriers of DNA-mismatch-repair genes | International Journal of Cancer | 1999 | 1,061 |
| 2 | Mammary Analogue Secretory Carcinoma of Salivary Glands, Containing the ETV6-NTRK3 Fusion Gene: A Hitherto Undescribed Salivary Gland Tumor Entity | American Journal of Surgical Pathology | 2010 | 857 |
| 3 | Occult papillary carcinoma of the thyroid. A “normal” finding in finland. A systematic autopsy study | Cancer | 1985 | 825 |
| 4 | Ornithine decarboxylase activity is critical for cell transformation | Nature | 1992 | 600 |
| 5 | Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells. | Journal of Biological Chemistry | 1994 | 588 |
| 6 | MED12 , the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomas | Science | 2011 | 547 |
| 7 | CD117: a sensitive marker for gastrointestinal stromal tumors that is more specific than CD34 | Modern Pathology | 1998 | 532 |
| 8 | Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells | Journal of Biological Chemistry | 1994 | 492 |
| 9 | Polarized Vascular Endothelial Growth Factor Secretion by Human Retinal Pigment Epithelium and Localization of Vascular Endothelial Growth Factor Receptors on the Inner Choriocapillaris | American Journal of Pathology | 1999 | 491 |
| 10 | VEGFR-3 and Its Ligand VEGF-C Are Associated with Angiogenesis in Breast Cancer | American Journal of Pathology | 1999 | 484 |
| 11 | Apolipoprotein E, Dementia, and Cortical Deposition of β-Amyloid Protein | New England Journal of Medicine | 1995 | 477 |
| 12 | Diverse functions of JNK signaling and c-Jun in stress response and apoptosis | Oncogene | 1999 | 476 |
| 13 | The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families | Nature Genetics | 1995 | 461 |
| 14 | Atypical and anaplastic meningiomas: Radiology, surgery, radiotherapy, and outcome | World Neurosurgery | 1986 | 458 |
| 15 | Deep learning based tissue analysis predicts outcome in colorectal cancer | Scientific Reports | 2018 | 450 |
| 16 | Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts | Nature Genetics | 2000 | 436 |
| 17 | K562—A human erythroleukemic cell line | International Journal of Cancer | 1979 | 429 |
| 18 | Appearance and distribution of collagens and laminin in the early mouse embryo | Developmental Biology | 1980 | 397 |
| 19 | Mutations of the Down–regulated in adenoma (DRA) gene cause congenital chloride diarrhoea | Nature Genetics | 1996 | 394 |
| 20 | Multiple sclerosis: In situ evidence for antibody- and complement-mediated demyelination | Annals of Neurology | 1998 | 390 |
| 21 | A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1 | Nature Medicine | 1998 | 347 |
| 22 | Mitochondrial ATP synthase subunitc storage in the ceroid-lipofuscinoses (Batten disease) | American Journal of Medical Genetics Part A | 1992 | 334 |
| 23 | Early organogenesis of the kidney | Pediatric Nephrology | 1987 | 323 |
| 24 | Arrhythmic disorder mapped to chromosome 1q42–q43 causes malignant polymorphic ventricular tachycardia in structurally normal hearts | Journal of the American College of Cardiology | 1999 | 321 |
| 25 | Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer | EMBO Journal | 2011 | 318 |
| 26 | Deletion of the paired alpha 5(IV) and alpha 6(IV) collagen genes in inherited smooth muscle tumors | Science | 1993 | 307 |
| 27 | Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer | Nature Genetics | 1994 | 304 |
| 28 | VEGF‐C and VEGF‐D expression in neuroendocrine cells and their receptor, VEGFR‐3, in fenestrated blood vessels in human tissues | FASEB Journal | 2000 | 299 |
| 29 | Molecular classification of mucoepidermoid carcinomas—Prognostic significance of theMECT1–MAML2 fusion oncogene | Genes Chromosomes and Cancer | 2006 | 297 |
| 30 | The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity. | EMBO Journal | 1992 | 294 |
| 31 | Expression patterns of neurotrophin and their receptor mRNAs in the rat inner ear | Hearing Research | 1993 | 292 |
| 32 | Association of Ezrin with Intercellular Adhesion Molecule-1 and -2 (ICAM-1 and ICAM-2) | Journal of Biological Chemistry | 1998 | 285 |
| 33 | Brain-derived neurotrophic factor and neurotrophin 3 mRNAs in the peripheral target fields of developing inner ear ganglia. | Proceedings of the National Academy of Sciences of the United States of America | 1992 | 283 |
| 34 | Postirradiation sarcoma. Analysis of a nationwide cancer registry material | Cancer | 1991 | 277 |
| 35 | An autosomal locus predisposing to deletions of mitochondrial DNA | Nature Genetics | 1995 | 268 |
| 36 | Pulmonary Vascular Endothelial Growth Factor and Flt-1 in Fetuses, in Acute and Chronic Lung Disease, and in Persistent Pulmonary Hypertension of the Newborn | American Journal of Respiratory and Critical Care Medicine | 2001 | 266 |
| 37 | Prognostic impact of immunohistochemically defined germinal center phenotype in diffuse large B-cell lymphoma patients treated with immunochemotherapy | Blood | 2007 | 260 |
| 38 | Long-Term Course and Consequences ofHelicobacter pylorigastritis Results of a 32-Year Follow-up Study | Scandinavian Journal of Gastroenterology | 1996 | 259 |
| 39 | Morphological and Functional Characterization of Isolated Effector Cells Responsible for Human Natural Killer Activity to Fetal Fibroblasts and to Cultured Cell Line Targets | Immunological Reviews | 1979 | 258 |
| 40 | Genetic and Epigenetic Modification of MLH1 Accounts for a Major Share of Microsatellite-Unstable Colorectal Cancers | American Journal of Pathology | 2000 | 255 |
| 41 | DAP12/TREM2 Deficiency Results in Impaired Osteoclast Differentiation and Osteoporotic Features | Journal of Experimental Medicine | 2003 | 253 |
| 42 | Griffonia simplicifolia lectins bind specifically to endothelial cells and some epithelial cells in mouse tissues | The Histochemical Journal | 1987 | 251 |
| 43 | Effect of Lactobacillus rhamnosus GG on ileal pouch inflammation and microbial flora | Alimentary Pharmacology and Therapeutics | 2003 | 248 |
| 44 | Tumor Necrosis Factor as a Potent Inhibitor of Adrenocorticotropin-Induced Cortisol Production and Steroidogenic P450 Enzyme Gene Expression in Cultured Human Fetal Adrenal Cells* | Endocrinology | 1991 | 246 |
| 45 | Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis | Development (Cambridge) | 1995 | 245 |
| 46 | The related FLT4, FLT1, and KDR receptor tyrosine kinases show distinct expression patterns in human fetal endothelial cells. | Journal of Experimental Medicine | 1993 | 241 |
| 47 | Depth of invasion, tumor budding, and worst pattern of invasion: Prognostic indicators in early‐stage oral tongue cancer | Head and Neck | 2014 | 241 |
| 48 | High frequency of BRAFV600E mutations in ameloblastoma | Journal of Pathology | 2014 | 240 |
| 49 | Secretion of active membrane type 1 matrix metalloproteinase (MMP‐14) into extracellular space in microvesicular exosomes | Journal of Cellular Biochemistry | 2008 | 238 |
| 50 | Distinct Populations of Stromal Cells Express Collagenase-3 (MMP-13) and Collagenase-1 (MMP-1) in Chronic Ulcers but Not in Normally Healing Wounds | Journal of Investigative Dermatology | 1997 | 233 |
