| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Management of high blood pressure in children and adolescents: recommendations of the European Society of Hypertension | Journal of Hypertension | 2009 | 620 |
| 3 | The preclinical pharmacology of roflumilast – A selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease | Pulmonary Pharmacology and Therapeutics | 2010 | 270 |
| 4 | Chemical Constituents and Pharmacological Properties ofPoria cocos | Planta Medica | 2011 | 268 |
| 5 | Anti-Inflammatory Actions of the Heme Oxygenase-1 Pathway | Current Pharmaceutical Design | 2003 | 215 |
| 6 | Idiopathic Pulmonary Fibrosis and Lung Cancer: Mechanisms and Molecular Targets | International Journal of Molecular Sciences | 2019 | 201 |
| 7 | Inducers of Heme Oxygenase-1 | Current Pharmaceutical Design | 2008 | 163 |
| 8 | Anti-Inflammatory Agents from Plants: Progress and Potential | Current Medicinal Chemistry | 2012 | 161 |
| 9 | Angiotensin II Induces Leukocyte–Endothelial Cell Interactions In Vivo Via AT1and AT2Receptor–Mediated P-Selectin Upregulation | Circulation | 2000 | 148 |
| 10 | Intestinal anti-inflammatory activity of ellagic acid in the acute and chronic dextrane sulfate sodium models of mice colitis | Journal of Ethnopharmacology | 2013 | 143 |
| 11 | Inflammasomes in Liver Fibrosis | Seminars in Liver Disease | 2017 | 143 |
| 12 | Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition | Thorax | 2012 | 140 |
| 13 | Endogenous nitric oxide as a mediator of gastric mucosal vasodilatation during acid secretion | Gastroenterology | 1992 | 132 |
| 14 | An updated overview of e-cigarette impact on human health | Respiratory Research | 2021 | 132 |
| 15 | Microneedle-Based Delivery: An Overview of Current Applications and Trends | Pharmaceutics | 2020 | 123 |
| 16 | Phosphodiesterase 4 inhibition decreases MUC5AC expression induced by epidermal growth factor in human airway epithelial cells | Thorax | 2005 | 122 |
| 17 | The JAK2 pathway is activated in idiopathic pulmonary fibrosis | Respiratory Research | 2018 | 122 |
| 18 | New molecular targets for the treatment of osteoarthritis | Biochemical Pharmacology | 2010 | 118 |
| 19 | Angiotensin II Induces Neutrophil Accumulation In Vivo Through Generation and Release of CXC Chemokines | Circulation | 2004 | 109 |
| 20 | Synergistic interaction between CCK and leptin to regulate food intake | Regulatory Peptides | 2000 | 108 |
| 21 | Role of JAK/STAT in Interstitial Lung Diseases; Molecular and Cellular Mechanisms | International Journal of Molecular Sciences | 2021 | 106 |
| 22 | Investigation into the role of phosphodiesterase IV in bronchorelaxation, including studies with human bronchus | British Journal of Pharmacology | 1993 | 105 |
| 23 | Induction of Oxidative Stress and Human Leukocyte/Endothelial Cell Interactions in Polycystic Ovary Syndrome Patients with Insulin Resistance | Journal of Clinical Endocrinology and Metabolism | 2011 | 104 |
| 24 | The carbon monoxide-releasing molecule CORM-2 inhibits the inflammatory response induced by cytokines in Caco-2 cells | British Journal of Pharmacology | 2007 | 101 |
| 25 | A History of the Pharmacological Treatment of Bipolar Disorder | International Journal of Molecular Sciences | 2018 | 101 |
| 26 | Programming of Intestinal Epithelial Differentiation by IL-33 Derived from Pericryptal Fibroblasts in Response to Systemic Infection | Cell Reports | 2016 | 100 |
| 27 | PDE4 inhibitors as new anti-inflammatory drugs: Effects on cell trafficking and cell adhesion molecules expression | | 2005 | 97 |
| 28 | OXIDATIVE STRESS AND PULMONARY INFLAMMATION: PHARMACOLOGICAL INTERVENTION WITH ANTIOXIDANTS | Pharmacological Research | 1999 | 96 |
| 29 | Angiotensin II-Induced Mononuclear Leukocyte Interactions with Arteriolar and Venular Endothelium Are Mediated by the Release of Different CC Chemokines | Journal of Immunology | 2006 | 95 |
| 30 | High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes | Arthritis Research and Therapy | 2010 | 95 |
| 31 | Deficiency of Nrf2 Accelerates the Effector Phase of Arthritis and Aggravates Joint Disease | Antioxidants and Redox Signaling | 2011 | 93 |
| 32 | Heme oxygenase-1 inhibits apoptosis in Caco-2 cells via activation of Akt pathway | International Journal of Biochemistry and Cell Biology | 2006 | 91 |
| 33 | Morelloflavone, a novel biflavonoid inhibitor of human secretory phospholipase A2 with anti-inflammatory activity | Biochemical Pharmacology | 1997 | 90 |
| 34 | OralN‐acetylcysteine attenuates the rat pulmonary inflammatory response to antigen | European Respiratory Journal | 2003 | 90 |
| 35 | Trans- but Not Cis-Resveratrol Impairs Angiotensin-II–Mediated Vascular Inflammation through Inhibition of NF-κB Activation and Peroxisome Proliferator-Activated Receptor-γ Upregulation | Journal of Immunology | 2010 | 89 |
| 36 | Mitochondria and T2D: Role of Autophagy, ER Stress, and Inflammasome | Trends in Endocrinology and Metabolism | 2020 | 88 |
| 37 | Pharmacological Characterization and Autoradiographic Localization of Histamine H2Receptors in Human Brain Identified with [125I]Iodoaminopotentidine | Journal of Neurochemistry | 1992 | 86 |
| 38 | Anti-Inflammatory and Antiallergic Activityin vivoof LipophilicIsatis tinctoriaExtracts and Tryptanthrin | Planta Medica | 2006 | 85 |
| 39 | Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin‐induced lung injury | British Journal of Pharmacology | 2009 | 85 |
| 40 | NF-κB and STAT3 Inhibition as a Therapeutic Strategy in Psoriasis: In Vitro and In Vivo Effects of BTH | Journal of Investigative Dermatology | 2013 | 85 |
| 41 | Effects of Nrf2 Deficiency on Bone Microarchitecture in an Experimental Model of Osteoporosis | Oxidative Medicine and Cellular Longevity | 2014 | 83 |
| 42 | The angiotensin‐(1‐7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation | Aging Cell | 2019 | 80 |
| 43 | Avarol and avarone, two new anti-inflammatory agents of marine origin | European Journal of Pharmacology | 1994 | 79 |
| 44 | Accelerated communication: Effects of flavonoids on Naja Naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice | Life Sciences | 1994 | 78 |
| 45 | Treatment with a CO-releasing molecule (CORM-3) reduces joint inflammation and erosion in murine collagen-induced arthritis | Annals of the Rheumatic Diseases | 2007 | 78 |
| 46 | Inhibition of Transcription Factors by Plant-Derived Compounds and their Implications in Inflammation and Cancer | Current Pharmaceutical Design | 2009 | 75 |
| 47 | Ex Vivo Tracking of Endogenous CO with a Ruthenium(II) Complex | Journal of the American Chemical Society | 2017 | 74 |
| 48 | Mitochondria, the NLRP3 Inflammasome, and Sirtuins in Type 2 Diabetes: New Therapeutic TargetsReviewing Editors:Markus Bachschmid, Dylan Burger, Vittorio Calabrese, Amadou Camara, Lukas Kubala, Giuseppe Poli, and Chandan K. Sen | Antioxidants and Redox Signaling | 2018 | 74 |
| 49 | Cell-Free Circulating Plasma hTERT mRNA Is a Useful Marker for Prostate Cancer Diagnosis and Is Associated with Poor Prognosis Tumor Characteristics | PLoS ONE | 2012 | 74 |
| 50 | Role of nuclear factor-κ B and heme oxygenase-1 in the mechanism of action of an anti-inflammatory chalcone derivative in RAW 264.7 cells | British Journal of Pharmacology | 2004 | 73 |
