| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 2 | TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2006 | 1,403 |
| 3 | A Randomized Trial of Laparoscopic versus Open Surgery for Rectal Cancer | New England Journal of Medicine | 2015 | 1,084 |
| 4 | Consensus Guidelines on the Testing and Clinical Management Issues Associated With HLA and Non-HLA Antibodies in Transplantation | Transplantation | 2013 | 679 |
| 5 | The natural history of primary and secondary malignant tumors of the liver I.The prognosis for patients with hepatic metastases from colonic and rectal carcinoma by laparotomy | Cancer | 1969 | 533 |
| 6 | Guidelines for the Diagnosis and Treatment of Neuroendocrine Gastrointestinal Tumours | Neuroendocrinology | 2004 | 422 |
| 7 | MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool | Nature | 2014 | 419 |
| 8 | A Review of the Evolution of Systemic Chemotherapy in the Management of Colorectal Cancer | Clinical Colorectal Cancer | 2015 | 391 |
| 9 | The Effect of Postoperative Intravenous Feeding (TPN) on Outcome Following Major Surgery Evaluated in a Randomized Study | Annals of Surgery | 1993 | 274 |
| 10 | Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types | Nature Genetics | 2014 | 269 |
| 11 | Survival benefit in a randomized clinical trial of faecal occult blood screening for colorectal cancer | British Journal of Surgery | 2008 | 264 |
| 12 | Body composition and time course changes in regional distribution of fat and lean tissue in unselected cancer patients on palliative care—Correlations with food intake, metabolism, exercise capacity, and hormones | Cancer | 2005 | 257 |
| 13 | Dietary intake and resting energy expenditure in relation to weight loss in unselected cancer patients | International Journal of Cancer | 2001 | 246 |
| 14 | Long-term results of a prospective randomized comparison of total fundic wrap (Nissen-Rossetti) or semifundoplication (Toupet) for gastro-oesophageal reflux | British Journal of Surgery | 2005 | 223 |
| 15 | Intermittent Claudication—Surgical Reconstruction or Physical Training? | Annals of Surgery | 1989 | 219 |
| 16 | BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 204 |
| 17 | Randomized clinical trial of the effect of interferon α on survival in patients with disseminated midgut carcinoid tumours | British Journal of Surgery | 2003 | 202 |
| 18 | High Expression of Complement Components in Omental Adipose Tissue in Obese Men | Obesity | 2003 | 195 |
| 19 | Palliative nutritional intervention in addition to cyclooxygenase and erythropoietin treatment for patients with malignant disease: Effects on survival, metabolism, and function | Cancer | 2004 | 194 |
| 20 | Anti-inflammatory treatment may prolong survival in undernourished patients with metastatic solid tumors | Cancer Research | 1994 | 190 |
| 21 | Laparoscopic Lavage Is Feasible and Safe for the Treatment of Perforated Diverticulitis With Purulent Peritonitis | Annals of Surgery | 2016 | 189 |
| 22 | RNAi delivery by exosome-mimetic nanovesicles – Implications for targeting c-Myc in cancer | Biomaterials | 2016 | 188 |
| 23 | The gut as the largest endocrine organ in the body | Annals of Oncology | 2001 | 170 |
| 24 | Randomized clinical trial of the costs of open and laparoscopic surgery for colonic cancer | British Journal of Surgery | 2004 | 166 |
| 25 | Diagnosis, treatment, and consequences of anastomotic leakage in colorectal surgery | International Journal of Colorectal Disease | 2017 | 165 |
| 26 | Skeletal muscle metabolism in patients with malignant tumor | European Journal of Cancer | 1976 | 161 |
| 27 | Current Response and Management Decisions of the European Union to the COVID-19 Outbreak: A Review | Sustainability | 2020 | 160 |
| 28 | Future cancer research priorities in the USA: a Lancet Oncology Commission | Lancet Oncology, The | 2017 | 153 |
| 29 | Rotavirus Stimulates Release of Serotonin (5-HT) from Human Enterochromaffin Cells and Activates Brain Structures Involved in Nausea and Vomiting | PLoS Pathogens | 2011 | 152 |
| 30 | Metabolism of adipose tissue in intraabdominal depots in severely obese men and women | Metabolism: Clinical and Experimental | 1990 | 151 |
| 31 | Transplantation of an allogeneic vein bioengineered with autologous stem cells: a proof-of-concept study | Lancet, The | 2012 | 151 |
| 32 | The influence of surgery on the risk of death in patients with primary hyperparathyroidism | World Journal of Surgery | 1991 | 141 |
| 33 | Muscle Enzyme Adaptation in Patients with Peripheral Arterial Insufficiency: Spontaneous Adaptation, Effect of Different Treatments and Consequences on Walking Performance | Clinical Science | 1989 | 140 |
| 34 | The Role of Cytokines, Coagulation, and Fibrinolysis in Peritoneal Tissue Repair | The European Journal of Surgery | 1999 | 140 |
| 35 | Orthotopic liver or multivisceral transplantation as treatment of metastatic neuroendocrine tumors | Liver Transplantation | 2007 | 139 |
| 36 | Early Complications After Laparoscopic Gastric Bypass Surgery | Annals of Surgery | 2014 | 139 |
| 37 | Fibrinolysis in human peritoneum during operation | Surgery | 1996 | 138 |
| 38 | Prognostic factors influencing relapse of oesophagitis during maintenance therapy with antisecretory drugs: a meta‐analysis of long‐term omeprazole trials | Alimentary Pharmacology and Therapeutics | 1997 | 137 |
| 39 | The lived experiences of adult intensive care patients who were conscious during mechanical ventilation: A phenomenological-hermeneutic study | Intensive and Critical Care Nursing | 2012 | 135 |
| 40 | Elevated energy expenditure in cancer patients with solid tumours | European Journal of Cancer & Clinical Oncology | 1991 | 132 |
| 41 | European Society of Coloproctology: guidelines for the management of diverticular disease of the colon | Colorectal Disease | 2020 | 132 |
| 42 | Subpopulations of extracellular vesicles from human metastatic melanoma tissue identified by quantitative proteomics after optimized isolation | Journal of Extracellular Vesicles | 2020 | 130 |
| 43 | Depression of peritoneal fibrinolysis during operation is a local response to trauma | Surgery | 1998 | 126 |
| 44 | Insulin Treatment in Cancer Cachexia: Effects on Survival, Metabolism, and Physical Functioning | Clinical Cancer Research | 2007 | 126 |
| 45 | Abdominal rectopexy for rectal prolapse | Diseases of the Colon and Rectum | 1994 | 122 |
| 46 | Human Mucosa-Associated Invariant T Cells Accumulate in Colon Adenocarcinomas but Produce Reduced Amounts of IFN-γ | Journal of Immunology | 2015 | 121 |
| 47 | Retrospective review of risk factors for surgical wound dehiscence and incisional hernia | BMC Surgery | 2017 | 121 |
| 48 | Does massive obesity promote abnormal gastroesophageal reflux? | Digestive Diseases and Sciences | 1995 | 119 |
| 49 | Loperamide improves anal sphincter function and continence after restorative proctocolectomy | Digestive Diseases and Sciences | 1994 | 118 |
| 50 | Diagnosis and treatment of superior mesenteric artery syndrome | British Journal of Surgery | 2005 | 118 |
