| # | Title | Journal | Year | Citations |
|---|
| 1 | Meiosis-Specific DNA Double-Strand Breaks Are Catalyzed by Spo11, a Member of a Widely Conserved Protein Family | Cell | 1997 | 1,640 |
| 2 | An atlas of human long non-coding RNAs with accurate 5′ ends | Nature | 2017 | 898 |
| 3 | Global functional profiling of gene expression☆☆This work was funded in part by a Sun Microsystems grant awarded to S.D., NIH Grant HD36512 to S.A.K., a Wayne State University SOM Dean’s Post-Doctoral Fellowship, and an NICHD Contraception and Infertility Loan to G.C.O. Support from the WSU MCBI mode is gratefully appreciated. | Genomics | 2003 | 544 |
| 4 | Genome-wide computational identification and manual annotation of human long noncoding RNA genes | Rna | 2010 | 354 |
| 5 | Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels | Biochemical and Biophysical Research Communications | 2012 | 311 |
| 6 | Essential Elements of Genetic Cancer Risk Assessment, Counseling, and Testing: Updated Recommendations of the National Society of Genetic Counselors | Journal of Genetic Counseling | 2012 | 287 |
| 7 | The oligodendrocyte-specific G protein–coupled receptor GPR17 is a cell-intrinsic timer of myelination | Nature Neuroscience | 2009 | 277 |
| 8 | Reliability of the CMT neuropathy score (second version) in Charcot‐Marie‐Tooth disease | Journal of the Peripheral Nervous System | 2011 | 269 |
| 9 | Deconstructing Adipogenesis Induced by β3-Adrenergic Receptor Activation with Single-Cell Expression Profiling | Cell Metabolism | 2018 | 250 |
| 10 | Social status alters immune regulation and response to infection in macaques | Science | 2016 | 235 |
| 11 | Genetic Cancer Risk Assessment and Counseling: Recommendations of the National Society of Genetic Counselors | Journal of Genetic Counseling | 2004 | 227 |
| 12 | Deafness in Claudin 11-Null Mice Reveals the Critical Contribution of Basal Cell Tight Junctions to Stria Vascularis Function | Journal of Neuroscience | 2004 | 225 |
| 13 | Single cell transcriptional signatures of the human placenta in term and preterm parturition | ELife | 2019 | 216 |
| 14 | Brain ischemia and reperfusion activates the eukaryotic initiation factor 2α kinase, PERK | Journal of Neurochemistry | 2001 | 209 |
| 15 | The Scientific Foundation for Personal Genomics: Recommendations from a National Institutes of Health–Centers for Disease Control and Prevention Multidisciplinary Workshop | Genetics in Medicine | 2009 | 207 |
| 16 | Integrating molecular QTL data into genome-wide genetic association analysis: Probabilistic assessment of enrichment and colocalization | PLoS Genetics | 2017 | 205 |
| 17 | Elevated circulating lipasin/betatrophin in human type 2 diabetes and obesity | Scientific Reports | 2014 | 204 |
| 18 | Metformin, the aspirin of the 21st century: its role in gestational diabetes mellitus, prevention of preeclampsia and cancer, and the promotion of longevity | American Journal of Obstetrics and Gynecology | 2017 | 183 |
| 19 | Human Procathepsin B Interacts with the Annexin II Tetramer on the Surface of Tumor Cells | Journal of Biological Chemistry | 2000 | 181 |
| 20 | The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking | Open Biology | 2016 | 179 |
| 21 | Mathematical model to predict regions of chromatin attachment to the nuclear matrix | Nucleic Acids Research | 1997 | 174 |
| 22 | Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility | Nature Communications | 2015 | 173 |
| 23 | TXNIP Links Innate Host Defense Mechanisms to Oxidative Stress and Inflammation in Retinal Muller Glia under Chronic Hyperglycemia: Implications for Diabetic Retinopathy | Experimental Diabetes Research | 2012 | 171 |
| 24 | Increased Survival and Function of SOD1 Mice After Glial Cell-Derived Neurotrophic Factor Gene Therapy | Human Gene Therapy | 2002 | 165 |
| 25 | The use of high-dimensional biology (genomics, transcriptomics, proteomics, and metabolomics) to understand the preterm parturition syndrome | BJOG: an International Journal of Obstetrics and Gynaecology | 2006 | 165 |
| 26 | Phylogenetic relationships and divergence times among New World monkeys (Platyrrhini, Primates) | Molecular Phylogenetics and Evolution | 2006 | 161 |
| 27 | Tissue‐specific regulation of cytochrome c by post‐translational modifications: respiration, the mitochondrial membrane potential, ROS, and apoptosis | FASEB Journal | 2019 | 159 |
| 28 | Unfolded protein response in cancer: the Physician's perspective | Journal of Hematology and Oncology | 2011 | 152 |
| 29 | Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2 | Nucleic Acids Research | 2013 | 146 |
| 30 | Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia | Frontiers in Immunology | 2018 | 146 |
| 31 | ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase | Molecular Metabolism | 2017 | 142 |
| 32 | C-peptide prevents and improves chronic Type I diabetic polyneuropathy in the BB/Wor rat | Diabetologia | 2001 | 139 |
| 33 | High-throughput allele-specific expression across 250 environmental conditions | Genome Research | 2016 | 138 |
| 34 | Microarray Profiling Reveals That Placental Transcriptomes of Early-onset HELLP Syndrome and Preeclampsia Are Similar | Placenta | 2011 | 119 |
| 35 | DEG 15, an update of the Database of Essential Genes that includes built-in analysis tools | Nucleic Acids Research | 2021 | 119 |
| 36 | Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family | Biochemical and Biophysical Research Communications | 2013 | 118 |
| 37 | Emerging roles of Lipasin as a critical lipid regulator | Biochemical and Biophysical Research Communications | 2013 | 118 |
| 38 | Maternal-fetal immune responses in pregnant women infected with SARS-CoV-2 | Nature Communications | 2022 | 117 |
| 39 | A molecular timescale for caviomorph rodents (Mammalia, Hystricognathi) | Molecular Phylogenetics and Evolution | 2005 | 114 |
| 40 | The transcriptome of the uterine cervix before and after spontaneous term parturition | American Journal of Obstetrics and Gynecology | 2006 | 114 |
| 41 | Delivery Of Cascade Screening For Hereditary Conditions: A Scoping Review Of The Literature | Health Affairs | 2018 | 114 |
| 42 | Neuropathy progression in Charcot-Marie-Tooth disease type 1A | Neurology | 2008 | 112 |
| 43 | Synaptogenesis and development of pyramidal neuron dendritic morphology in the chimpanzee neocortex resembles humans | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 112 |
| 44 | A fully resolved genus level phylogeny of neotropical primates (Platyrrhini) | Molecular Phylogenetics and Evolution | 2009 | 102 |
| 45 | Histone Acetylation and Recruitment of Serum Responsive Factor and CREB-Binding Protein Onto SM22 Promoter During SM22 Gene Expression | Circulation Research | 2002 | 98 |
| 46 | An explanation for recent discrepancies in levels of human circulating betatrophin | Diabetologia | 2014 | 95 |
| 47 | Heterogeneous Duplications in Patients with Pelizaeus-Merzbacher Disease Suggest a Mechanism of Coupled Homologous and Nonhomologous Recombination | American Journal of Human Genetics | 2005 | 93 |
| 48 | Cross-Population Joint Analysis of eQTLs: Fine Mapping and Functional Annotation | PLoS Genetics | 2015 | 93 |
| 49 | The DNA damage-recognition problem in human and other eukaryotic cells: the XPA damage binding protein | Biochemical Journal | 1997 | 92 |
| 50 | Evolutionary origins of the placental expression of chromosome 19 cluster galectins and their complex dysregulation in preeclampsia | Placenta | 2014 | 92 |
