| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2005 | 595 |
| 3 | Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway | Cancer Research | 2009 | 576 |
| 4 | Disulfiram, a Clinically Used Anti-Alcoholism Drug and Copper-Binding Agent, Induces Apoptotic Cell Death in Breast Cancer Cultures and Xenografts via Inhibition of the Proteasome Activity | Cancer Research | 2006 | 559 |
| 5 | Celastrol, a Triterpene Extracted from the Chinese “Thunder of God Vine,” Is a Potent Proteasome Inhibitor and Suppresses Human Prostate Cancer Growth in Nude Mice | Cancer Research | 2006 | 551 |
| 6 | Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation | American Journal of Physiology - Cell Physiology | 1997 | 465 |
| 7 | IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells | American Journal of Physiology - Renal Physiology | 2000 | 418 |
| 8 | Gemcitabine Sensitivity Can Be Induced in Pancreatic Cancer Cells through Modulation of miR-200 and miR-21 Expression by Curcumin or Its Analogue CDF | Cancer Research | 2010 | 413 |
| 9 | PER2 Controls Lipid Metabolism by Direct Regulation of PPARγ | Cell Metabolism | 2010 | 400 |
| 10 | Hypoxia-Inducible Factor 1–Dependent Induction of Intestinal Trefoil Factor Protects Barrier Function during Hypoxia | Journal of Experimental Medicine | 2001 | 386 |
| 11 | Inhibition of Human Cancer Cell Growth and Metastasis in Nude Mice by Oral Intake of Modified Citrus Pectin | Journal of the National Cancer Institute | 2002 | 368 |
| 12 | A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease | Gastroenterology | 2002 | 337 |
| 13 | Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance | Drug Resistance Updates | 2010 | 313 |
| 14 | Widespread Alterations of α-Synuclein in Multiple System Atrophy | American Journal of Pathology | 1999 | 305 |
| 15 | Pancreatic cancer: understanding and overcoming chemoresistance | Nature Reviews Gastroenterology and Hepatology | 2011 | 303 |
| 16 | A Novel Anticancer Gold(III) Dithiocarbamate Compound Inhibits the Activity of a Purified 20S Proteasome and 26S Proteasome in Human Breast Cancer Cell Cultures and Xenografts | Cancer Research | 2006 | 302 |
| 17 | Dietary flavonoids as proteasome inhibitors and apoptosis inducers in human leukemia cells | Biochemical Pharmacology | 2005 | 298 |
| 18 | Curcumin Analogue CDF Inhibits Pancreatic Tumor Growth by Switching on Suppressor microRNAs and Attenuating EZH2 Expression | Cancer Research | 2012 | 285 |
| 19 | Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells | Breast Cancer Research | 2005 | 284 |
| 20 | Biliary intraepithelial neoplasia: an international interobserver agreement study and proposal for diagnostic criteria | Modern Pathology | 2007 | 271 |
| 21 | The Role of Notch Signaling Pathway in Epithelial-Mesenchymal Transition (EMT) During Development and Tumor Aggressiveness | Current Drug Targets | 2010 | 271 |
| 22 | Genetic, Immunohistochemical, and Clinical Features of Medullary Carcinoma of the Pancreas | American Journal of Pathology | 2000 | 263 |
| 23 | Polarized Expression of Ca2+ Channels in Pancreatic and Salivary Gland Cells | Journal of Biological Chemistry | 1997 | 259 |
| 24 | Platelets and cancer: a casual or causal relationship: revisited | Cancer and Metastasis Reviews | 2014 | 258 |
| 25 | Alzheimer-Like Changes in Rat Models of Spontaneous Diabetes | Diabetes | 2007 | 252 |
| 26 | Kinetic Analysis of the Binding of Human Matrix Metalloproteinase-2 and -9 to Tissue Inhibitor of Metalloproteinase (TIMP)-1 and TIMP-2 | Journal of Biological Chemistry | 1997 | 251 |
| 27 | Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers | Molecular Carcinogenesis | 2008 | 249 |
| 28 | Dpc-4 Protein Is Expressed in Virtually All Human Intraductal Papillary Mucinous Neoplasms of the Pancreas | American Journal of Pathology | 2000 | 245 |
| 29 | Curcumin Inhibits the Proteasome Activity in Human Colon Cancer Cells In vitro and In vivo | Cancer Research | 2008 | 242 |
| 30 | Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2) | Cancer Research | 1995 | 241 |
| 31 | Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead | Carcinogenesis | 2015 | 239 |
| 32 | Down-regulation of Forkhead Box M1 Transcription Factor Leads to the Inhibition of Invasion and Angiogenesis of Pancreatic Cancer Cells | Cancer Research | 2007 | 233 |
| 33 | Diabetic neuropathy and oxidative stress | Diabetes/Metabolism Research and Reviews | 2006 | 232 |
| 34 | Experimental diabetic neuropathy: an update | Diabetologia | 1999 | 228 |
| 35 | BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) Mutations in Distinct Subsets of Pancreatic Cancer | American Journal of Pathology | 2003 | 225 |
| 36 | Assessment of Gelatinases (MMP-2 and MMP-9) by Gelatin Zymography | Methods in Molecular Biology | 2012 | 225 |
| 37 | PAMAM dendrimers as promising nanocarriers for RNAi therapeutics | Materials Today | 2015 | 219 |
| 38 | A Novel Prodrug of the Green Tea Polyphenol (−)-Epigallocatechin-3-Gallate as a Potential Anticancer Agent | Cancer Research | 2007 | 218 |
| 39 | Overview of Cancer Stem Cells (CSCs) and Mechanisms of Their Regulation: Implications for Cancer Therapy | Current Protocols in Pharmacology | 2013 | 210 |
| 40 | Pathogenesis of invasive micropapillary carcinoma: role of MUC1 glycoprotein | Modern Pathology | 2004 | 208 |
| 41 | The Tumor Proteasome Is a Primary Target for the Natural Anticancer Compound Withaferin A Isolated from “Indian Winter Cherry” | Molecular Pharmacology | 2007 | 203 |
| 42 | Cell cycle arrest and inhibition of anoikis by galectin-3 in human breast epithelial cells | Cancer Research | 1999 | 201 |
| 43 | Over‐expression of FoxM1 leads to epithelial–mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells | Journal of Cellular Biochemistry | 2011 | 199 |
| 44 | Clioquinol, a Therapeutic Agent for Alzheimer's Disease, Has Proteasome-Inhibitory, Androgen Receptor–Suppressing, Apoptosis-Inducing, and Antitumor Activities in Human Prostate Cancer Cells and Xenografts | Cancer Research | 2007 | 196 |
| 45 | Pathways of Arsenic Uptake and Efflux | Current Topics in Membranes | 2012 | 196 |
| 46 | Nuclear Export of Phosphorylated Galectin-3 Regulates Its Antiapoptotic Activity in Response to Chemotherapeutic Drugs | Molecular and Cellular Biology | 2004 | 195 |
| 47 | Molecular Basis of Anthracycline-Induced Cardiotoxicity and Its Prevention | Molecular Genetics and Metabolism | 2000 | 191 |
| 48 | Cystic lesions of the pancreas | Modern Pathology | 2007 | 191 |
| 49 | Anti-Tumor Activity of a Novel Compound-CDF Is Mediated by Regulating miR-21, miR-200, and PTEN in Pancreatic Cancer | PLoS ONE | 2011 | 187 |
| 50 | Discoidin Domain Receptors: Unique Receptor Tyrosine Kinases in Collagen-mediated Signaling | Journal of Biological Chemistry | 2013 | 182 |
