| # | Title | Journal | Year | Citations |
|---|
| 1 | Photodynamic Therapy | Journal of the National Cancer Institute | 1998 | 4,721 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Neonatal Outcomes of Extremely Preterm Infants From the NICHD Neonatal Research Network | Pediatrics | 2010 | 2,252 |
| 4 | Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501) | Head and Neck | 2005 | 1,412 |
| 5 | multifunctional enzymes in cancer | Nature Reviews Cancer | 2006 | 1,134 |
| 6 | Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer | New England Journal of Medicine | 2021 | 1,042 |
| 7 | Combined therapy for cancer of the anal canal | Diseases of the Colon and Rectum | 1974 | 928 |
| 8 | Plasma norepinephrine in congestive heart failure | American Journal of Cardiology | 1978 | 927 |
| 9 | An atlas of human long non-coding RNAs with accurate 5′ ends | Nature | 2017 | 898 |
| 10 | Age‐associated memory impairment: Proposed diagnostic criteria and measures of clinical change — report of a national institute of mental health work group | Developmental Neuropsychology | 1986 | 852 |
| 11 | Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectives | Current Cancer Drug Targets | 2011 | 671 |
| 12 | Biochemistry of arsenic detoxification | FEBS Letters | 2002 | 663 |
| 13 | Disulfiram, a Clinically Used Anti-Alcoholism Drug and Copper-Binding Agent, Induces Apoptotic Cell Death in Breast Cancer Cultures and Xenografts via Inhibition of the Proteasome Activity | Cancer Research | 2006 | 559 |
| 14 | Celastrol, a Triterpene Extracted from the Chinese “Thunder of God Vine,” Is a Potent Proteasome Inhibitor and Suppresses Human Prostate Cancer Growth in Nude Mice | Cancer Research | 2006 | 551 |
| 15 | Connecting copper and cancer: from transition metal signalling to metalloplasia | Nature Reviews Cancer | 2022 | 519 |
| 16 | Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4 | Nature | 2017 | 516 |
| 17 | Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation | Nature | 2008 | 508 |
| 18 | Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: a pooled analysis within the InterLymph Consortium | Blood | 2008 | 508 |
| 19 | Incidence of cancer in children in the United States. Sex-, race-, and 1-year age-specific rates by histologic type | Cancer | 1995 | 496 |
| 20 | Oxidation of methane by a biological dicopper centre | Nature | 2010 | 477 |
| 21 | CopA: An Escherichia coli Cu(I)-translocating P-type ATPase | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 467 |
| 22 | Fungemia Caused by Candida Species and Torulopsis glabrata in the Hospitalized Patient: Frequency, Characteristics, and Evaluation of Factors Influencing Outcome | Clinical Infectious Diseases | 1989 | 459 |
| 23 | Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9 | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 455 |
| 24 | Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J | Nature | 2007 | 438 |
| 25 | Epidemiology of urinary tract infections | Infectious Disease Clinics of North America | 2003 | 437 |
| 26 | Zinc: role in immunity, oxidative stress and chronic inflammation | Current Opinion in Clinical Nutrition and Metabolic Care | 2009 | 434 |
| 27 | Sleep Loss and REM Sleep Loss are Hyperalgesic | Sleep | 2006 | 432 |
| 28 | Novel Metals and Metal Complexes as Platforms for Cancer Therapy | Current Pharmaceutical Design | 2010 | 427 |
| 29 | Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: Their role and involvement in neurological disorders | Brain Research Reviews | 2006 | 417 |
| 30 | Effect of nutrients on growth and lipid accumulation in the green algae Dunaliella tertiolecta | Bioresource Technology | 2011 | 408 |
| 31 | Evolution of EF-hand calcium-modulated proteins. I. Relationships based on amino acid sequences | Journal of Molecular Evolution | 1990 | 401 |
| 32 | Prenatal Alcohol Exposure and Childhood Behavior at Age 6 to 7 Years: I. Dose-Response Effect | Pediatrics | 2001 | 390 |
| 33 | Intracerebroventricular Leptin Increases Lumbar and Renal Sympathetic Nerve Activity and Blood Pressure in Normal Rats | Diabetes | 1997 | 386 |
| 34 | Immune cells in term and preterm labor | Cellular and Molecular Immunology | 2014 | 384 |
| 35 | Mitochondrial Dysfunction and Calcium Perturbation Induced by Traumatic Brain Injury | Journal of Neurotrauma | 1997 | 381 |
| 36 | Broad targeting of angiogenesis for cancer prevention and therapy | Seminars in Cancer Biology | 2015 | 375 |
| 37 | Inhibition of Human Cancer Cell Growth and Metastasis in Nude Mice by Oral Intake of Modified Citrus Pectin | Journal of the National Cancer Institute | 2002 | 368 |
| 38 | Long noncoding RNAs are rarely translated in two human cell lines | Genome Research | 2012 | 346 |
| 39 | Is phosphatidic acid a calcium ionophore under neurohumoral control? | Nature | 1980 | 340 |
| 40 | Disposition of intravenous and oral cyclosporine after administration with grapefruit juice* | Clinical Pharmacology and Therapeutics | 1995 | 335 |
| 41 | Global burden of recurrent vulvovaginal candidiasis: a systematic review | Lancet Infectious Diseases, The | 2018 | 334 |
| 42 | Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia | Journal of Maternal-Fetal and Neonatal Medicine | 2005 | 332 |
| 43 | Families of arsenic transporters | Trends in Microbiology | 1999 | 330 |
| 44 | 17 beta-Estradiol attenuates voltage-dependent Ca2+ currents in A7r5 vascular smooth muscle cell line | American Journal of Physiology - Cell Physiology | 1994 | 329 |
| 45 | First-year medical students prefer multiple learning styles | American Journal of Physiology - Advances in Physiology Education | 2006 | 324 |
| 46 | In Vitro Activities of Daptomycin, Vancomycin, Linezolid, and Quinupristin-Dalfopristin against Staphylococci and Enterococci, Including Vancomycin- Intermediate and -Resistant Strains | Antimicrobial Agents and Chemotherapy | 2000 | 321 |
| 47 | Serotonin as a developmental signal | Behavioural Brain Research | 1995 | 320 |
| 48 | Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention | Biochimica Et Biophysica Acta - Bioenergetics | 2002 | 313 |
| 49 | Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance | Drug Resistance Updates | 2010 | 313 |
| 50 | Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels | Biochemical and Biophysical Research Communications | 2012 | 311 |
