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Top Articles

#TitleJournalYearCitations
1Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicityNature2022756
2Integrated molecular analysis of adult T cell leukemia/lymphomaNature Genetics2015659
3Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancersNature2016536
4Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutationNature2022428
5Caspases Are Activated in a Branched Protease Cascade and Control Distinct Downstream Processes in Fas-induced ApoptosisJournal of Experimental Medicine1998423
6Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromesNature Medicine2020372
7 -Klotho as a Regulator of Calcium HomeostasisScience2007371
8PD-1–PD-1 ligand interaction contributes to immunosuppressive microenvironment of Hodgkin lymphomaBlood2008362
9Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysisInternational Immunology2006320
10Virological characteristics of the SARS-CoV-2 Omicron BA.2 spikeCell2022273
11Molecular International Prognostic Scoring System for Myelodysplastic SyndromesCell2022259
12Transplantation of allogeneic hematopoietic stem cells for adult T-cell leukemia: a nationwide retrospective studyBlood2010255
13A Novel Association of Fc Receptor γ-Chain with Glycoprotein VI and Their Co-expression as a Collagen Receptor in Human PlateletsJournal of Biological Chemistry1997253
14Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammationJournal of Experimental Medicine2011233
15Physical and Functional Association of the Src Family Kinases Fyn and Lyn with the Collagen Receptor Glycoprotein VI-Fc Receptor γ Chain Complex on Human PlateletsJournal of Experimental Medicine1998211
16Down-regulation of hepcidin resulting from long-term treatment with an anti–IL-6 receptor antibody (tocilizumab) improves anemia of inflammation in multicentric Castleman diseaseBlood2010204
17MicroRNA‐33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE −/− MiceJournal of the American Heart Association2012196
18Retrospective nationwide survey of Japanese patients with transfusion-dependent MDS and aplastic anemia highlights the negative impact of iron overload on morbidity/mortalityEuropean Journal of Haematology2007193
19Epigenetic Variation between Human Induced Pluripotent Stem Cell Lines Is an Indicator of Differentiation CapacityCell Stem Cell2016179
20The Enzymatic Activity of CEM15/Apobec-3G Is Essential for the Regulation of the Infectivity of HIV-1 Virion but Not a Sole Determinant of Its Antiviral ActivityJournal of Biological Chemistry2003171
21Proposed diagnostic criteria, disease severity classification and treatment strategy for TAFRO syndrome, 2015 versionInternational Journal of Hematology2016170
22Ceramide-induced Translocation of Protein Kinase C-δ and -ϵ to the CytosolJournal of Biological Chemistry1997164
23Graft-Versus-Host Disease Amelioration by Human Bone Marrow Mesenchymal Stromal/Stem Cell-Derived Extracellular Vesicles Is Associated with Peripheral Preservation of Naive T Cell PopulationsStem Cells2018162
24Allogeneic hematopoietic stem cell transplantation for adult T-cell leukemia-lymphoma with special emphasis on preconditioning regimen: a nationwide retrospective studyBlood2012156
25The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistanceCell Reports2022148
26Collagen-stimulated Activation of Syk but Not c-Src Is Severely Compromised in Human Platelets Lacking Membrane Glycoprotein VIJournal of Biological Chemistry1997146
27Ubiquitination of APOBEC3G by an HIV-1 Vif-Cullin5-Elongin B-Elongin C Complex Is Essential for Vif FunctionJournal of Biological Chemistry2005142
28Natural type I interferon-producing cells as a link between innate and adaptive immunityHuman Immunology2002140
29SARS-CoV-2 B.1.617 Mutations L452R and E484Q Are Not Synergistic for Antibody EvasionJournal of Infectious Diseases2021136
30Characterization of zebrafish caspase-3 and induction of apoptosis through ceramide generation in fish fathead minnow tailbud cells and zebrafish embryoBiochemical Journal2001134
31Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formationBiochemical and Biophysical Research Communications2014131
32Anti-viral protein APOBEC3G is induced by interferon-α stimulation in human hepatocytesBiochemical and Biophysical Research Communications2006127
33Ceramide Generation in Nitric Oxide-induced ApoptosisJournal of Biological Chemistry1999124
34Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphomaBlood2018124
35RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous RecombinationMolecular Cell2017123
36B7‐H1 expression is regulated by MEK/ERK signaling pathway in anaplastic large cell lymphoma and Hodgkin lymphomaCancer Science2009122
37Regulation of Autophagy and Its Associated Cell Death by “Sphingolipid Rheostat”Journal of Biological Chemistry2012120
38Affinity labeling displays the stepwise activation of ICE-related proteases by Fas, staurosporine, and CrmA-sensitive caspase-8Oncogene1997118
39APOBEC3G targets human T-cell leukemia virus type 1Retrovirology2005117
40Possible role of ceramide as an indicator of chemoresistance: decrease of the ceramide content via activation of glucosylceramide synthase and sphingomyelin synthase in chemoresistant leukemiaClinical Cancer Research2003115
41APOBEC3G Targets Specific Virus SpeciesJournal of Virology2004112
42Impact of graft-versus-host disease on outcomes after allogeneic hematopoietic cell transplantation for adult T-cell leukemia: a retrospective cohort studyBlood2012110
43Natural Alpha Interferon-Producing Cells Respond to Human Immunodeficiency Virus Type 1 with Alpha Interferon Production and Maturation into Dendritic CellsJournal of Virology2003106
44Prognostic impact of low allelic ratio FLT3-ITD and NPM1 mutation in acute myeloid leukemiaBlood Advances2018106
45Singlet oxygen is essential for neutrophil extracellular trap formationBiochemical and Biophysical Research Communications2011105
46CD5-positive diffuse large B-cell lymphoma: a retrospective study in 337 patients treated by chemotherapy with or without rituximabAnnals of Oncology2011103
47Gastrointestinal follicular lymphoma: review of the literatureJournal of Gastroenterology2010100
48Virus-stimulated plasmacytoid dendritic cells induce CD4+ cytotoxic regulatory T cellsBlood200697
49Serum Neutrophil Extracellular Trap Levels Predict Thrombotic Microangiopathy after Allogeneic Stem Cell TransplantationBiology of Blood and Marrow Transplantation201397
50Calpain-mediated X-linked Inhibitor of Apoptosis Degradation in Neutrophil Apoptosis and Its Impairment in Chronic Neutrophilic LeukemiaJournal of Biological Chemistry200296