| # | Title | Journal | Year | Citations |
|---|
| 1 | Modified XELIRI (capecitabine plus irinotecan) versus FOLFIRI (leucovorin, fluorouracil, and irinotecan), both either with or without bevacizumab, as second-line therapy for metastatic colorectal cancer (AXEPT): a multicentre, open-label, randomised, non-inferiority, phase 3 trial | Lancet Oncology, The | 2018 | 107 |
| 2 | Comparison of long-term survival outcomes between stereotactic body radiotherapy and sublobar resection for stage I non-small-cell lung cancer in patients at high risk for lobectomy: A propensity score matching analysis | European Journal of Cancer | 2014 | 93 |
| 3 | Video-Assisted Thoracoscopic Lobectomy Versus Stereotactic Radiotherapy for Stage I Lung Cancer | Annals of Thoracic Surgery | 2015 | 87 |
| 4 | Bevacizumab plus erlotinib versus erlotinib alone in Japanese patients with advanced, metastatic, EGFR-mutant non-small-cell lung cancer (NEJ026): overall survival analysis of an open-label, randomised, multicentre, phase 3 trial | Lancet Respiratory Medicine,the | 2022 | 62 |
| 5 | Phase 3 Trial Comparing Nanoparticle Albumin-Bound Paclitaxel With Docetaxel for Previously Treated Advanced NSCLC | Journal of Thoracic Oncology | 2021 | 57 |
| 6 | Magnifying endoscope with NBI to predict the depth of invasion in laryngo‐pharyngeal cancer | Laryngoscope | 2015 | 42 |
| 7 | A Prospective, Randomized Phase II Study of Adjuvant Gemcitabine Versus S-1 After Major Hepatectomy for Biliary Tract Cancer (KHBO 1208) | Annals of Surgery | 2019 | 41 |
| 8 | Randomised phase III study of S-1 alone versus S-1 plus lentinan for unresectable or recurrent gastric cancer (JFMC36-0701) | European Journal of Cancer | 2016 | 40 |
| 9 | International Retrospective Cohort Study of Conversion Therapy for Stage IV Gastric Cancer 1 (CONVO‐GC‐1) | Annals of Gastroenterological Surgery | 2022 | 39 |
| 10 | Breathing–swallowing discoordination is associated with frequent exacerbations of COPD | BMJ Open Respiratory Research | 2017 | 38 |
| 11 | Final overall survival results of WJTOG 3405, a randomized phase 3 trial comparing gefitinib (G) with cisplatin plus docetaxel (CD) as the first-line treatment for patients with non-small cell lung cancer (NSCLC) harboring mutations of the epidermal growth factor receptor (EGFR). | Journal of Clinical Oncology | 2014 | 36 |
| 12 | Factors associated with the achievement of biological disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: the ANSWER cohort study | Arthritis Research and Therapy | 2018 | 33 |
| 13 | Flexible next‐generation robotic surgical system for transoral endoscopic hypopharyngectomy: A comparative preclinical study | Head and Neck | 2018 | 32 |
| 14 | Induced pluripotent stem cell–based Drug Repurposing for Amyotrophic lateral sclerosis Medicine (iDReAM) study: protocol for a phase I dose escalation study of bosutinib for amyotrophic lateral sclerosis patients | BMJ Open | 2019 | 32 |
| 15 | A Randomized Controlled Trial of Telemedicine for Long-Term Sleep Apnea Continuous Positive Airway Pressure Management | Annals of the American Thoracic Society | 2020 | 31 |
| 16 | Prognostic model for survival based on readily available pretreatment factors in patients with advanced pancreatic cancer receiving palliative chemotherapy | International Journal of Clinical Oncology | 2016 | 28 |
| 17 | Carbamylated albumin is one of the target antigens of anti-carbamylated protein antibodies | Rheumatology | 2017 | 27 |
| 18 | Serum milk fat globule epidermal growth factor 8 elevation may subdivide systemic lupus erythematosus into two pathophysiologically distinct subsets | Lupus | 2014 | 26 |
| 19 | Altered expression of major immune regulatory molecules in peripheral blood immune cells associated with breast cancer | Breast Cancer | 2017 | 21 |
| 20 | Impact of imbalanced graft-to-spleen volume ratio on outcomes following living donor liver transplantation in an era when simultaneous splenectomy is not typically indicated | American Journal of Transplantation | 2019 | 21 |
| 21 | Interleukin-18 is associated with the presence of interstitial lung disease in rheumatoid arthritis: a cross-sectional study | Scandinavian Journal of Rheumatology | 2019 | 20 |
| 22 | Survival Benefit of and Indications for Adjuvant Chemotherapy for Resected Colorectal Liver Metastases—a Japanese Nationwide Survey | Journal of Gastrointestinal Surgery | 2020 | 19 |
| 23 | Reminiscence therapy using virtual reality technology affects cognitive function and subjective well-being in older adults with dementia | Cogent Psychology | 2021 | 18 |
| 24 | A randomized phase III trial of mFOLFOX6 plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment for metastatic colorectal cancer: West Japan Oncology Group study 4407G (WJOG4407G). | Journal of Clinical Oncology | 2014 | 18 |
| 25 | S-1 and oxaliplatin (SOX) plus bevacizumab versus mFOLFOX6 plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer: updated overall survival analyses of the open-label, non-inferiority, randomised phase III: SOFT study | ESMO Open | 2017 | 17 |
| 26 | Comprehensive data of 3,820 patients newly diagnosed with colorectal liver metastasis between 2005 and 2007: report of a nationwide survey in Japan | Journal of Hepato-Biliary-Pancreatic Sciences | 2018 | 17 |
| 27 | The clinical impact of Hangeshashinto (TJ-14) in the treatment of chemotherapy-induced oral mucositis in gastric cancer and colorectal cancer: Analyses of pooled data from two phase II randomized clinical trials (HANGESHA-G and HANGESHA-C) | Journal of Cancer | 2018 | 17 |
| 28 | Gene expression profile of peripheral blood mononuclear cells may contribute to the identification and immunological classification of breast cancer patients | Breast Cancer | 2019 | 17 |
| 29 | A phase 1 study of oral ASP5878, a selective small-molecule inhibitor of fibroblast growth factor receptors 1–4, as a single dose and multiple doses in patients with solid malignancies | Investigational New Drugs | 2020 | 16 |
| 30 | Prognostic significance of natriuretic peptide levels in atrial fibrillation without heart failure | Heart | 2021 | 16 |
| 31 | Durable tumor remission in patients with platinum-resistant ovarian cancer receiving nivolumab. | Journal of Clinical Oncology | 2015 | 16 |
| 32 | Japanese Lung Cancer Society Guidelines for Stage IV NSCLC With EGFR Mutations | JTO Clinical and Research Reports | 2021 | 15 |
| 33 | Anti–USAG-1 therapy for tooth regeneration through enhanced BMP signaling | Science Advances | 2021 | 15 |
| 34 | Phenotyping of IgG4-related diseases based on affected organ pattern: A multicenter cohort study using cluster analysis | Modern Rheumatology | 2021 | 14 |
| 35 | Proton Pump Inhibitor Use and the Efficacy of Chemotherapy in Metastatic Colorectal Cancer: A Post Hoc Analysis of a Randomized Phase III Trial (AXEPT) | Oncologist | 2021 | 14 |
| 36 | Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages | Circulation | 2022 | 14 |
| 37 | The lack of increases in circulating endothelial progenitor cell as a negative predictor for pathological response to neoadjuvant chemotherapy in breast cancer patients | Npj Precision Oncology | 2017 | 13 |
| 38 | Detection of atypical data in multicenter clinical trials using unsupervised statistical monitoring | Clinical Trials | 2019 | 13 |
| 39 | Bone mineral density correlates with survival after resection of extrahepatic biliary malignancies | Clinical Nutrition | 2019 | 13 |
| 40 | Long‐term outcome of liver resection for colorectal metastases in the presence of extrahepatic disease: A multi‐institutional Japanese study | Journal of Hepato-Biliary-Pancreatic Sciences | 2020 | 13 |
| 41 | Study protocol of the Asian XELIRI ProjecT (AXEPT): a multinational, randomized, non-inferiority, phase III trial of second-line chemotherapy for metastatic colorectal cancer, comparing the efficacy and safety of XELIRI with or without bevacizumab versus FOLFIRI with or without bevacizumab | Chinese Journal of Cancer | 2016 | 12 |
| 42 | A prospective Phase II study to examine the relationship between quality of life and adverse events of first‐line chemotherapy plus cetuximab in patients with KRAS wild‐type unresectable metastatic colorectal cancer: QUACK trial | Cancer Medicine | 2018 | 12 |
| 43 | Non-obese visceral adiposity is associated with the risk of atherosclerosis in Japanese patients with rheumatoid arthritis: a cross-sectional study | Rheumatology International | 2018 | 12 |
| 44 | Survival impact of treatment for chronic obstructive pulmonary disease in patients with advanced non-small-cell lung cancer | Scientific Reports | 2021 | 12 |
| 45 | A phase II trial of capecitabine plus cisplatin (XP) for patients with advanced gastric cancer with early relapse after S-1 adjuvant therapy: XParTS-I trial | Gastric Cancer | 2018 | 11 |
| 46 | A randomised phase II trial of capecitabine plus cisplatin versus S-1 plus cisplatin as a first-line treatment for advanced gastric cancer: Capecitabine plus cisplatin ascertainment versus S-1 plus cisplatin randomised PII trial (XParTS II) | European Journal of Cancer | 2018 | 11 |
| 47 | Third Dentition Is the Main Cause of Premolar Supernumerary Tooth Formation | Journal of Dental Research | 2019 | 11 |
| 48 | Assessment of autonomic nervous system function in nursing students using an autonomic reflex orthostatic test by heart rate spectral analysis | Biomedical Reports | 2015 | 10 |
| 49 | A High Portal Venous Pressure Gradient Increases Gut-Related Bacteremia and Consequent Early Mortality After Living Donor Liver Transplantation | Transplantation | 2018 | 10 |
| 50 | Long-term preservation of planar cell polarity in reversed tracheal epithelium | Respiratory Research | 2018 | 10 |
