| # | Title | Journal | Year | Citations |
|---|
| 1 | Gene Expression Levels and Immunolocalization of Organic Ion Transporters in the Human Kidney | Journal of the American Society of Nephrology: JASN | 2002 | 450 |
| 2 | Cellular and molecular aspects of drug transport in the kidney | Kidney International | 2000 | 404 |
| 3 | Identification and Functional Characterization of a New Human Kidney–Specific H+/Organic Cation Antiporter, Kidney-Specific Multidrug and Toxin Extrusion 2 | Journal of the American Society of Nephrology: JASN | 2006 | 348 |
| 4 | cDNA Cloning and Functional Expression of a Novel Rat Kidney Organic Cation Transporter, OCT2 | Biochemical and Biophysical Research Communications | 1996 | 335 |
| 5 | Metformin is a Superior Substrate for Renal Organic Cation Transporter OCT2 rather than Hepatic OCT1 | Drug Metabolism and Pharmacokinetics | 2005 | 313 |
| 6 | Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1) | Journal of Pharmacology and Experimental Therapeutics | 1992 | 261 |
| 7 | Immuno-Localization of H+/Peptide Cotransporter in Rat Digestive Tract | Biochemical and Biophysical Research Communications | 1996 | 213 |
| 8 | Cloning and Functional Characterization of a Novel Rat Organic Anion Transporter Mediating Basolateral Uptake of Methotrexate in the Kidney | Journal of Biological Chemistry | 1996 | 182 |
| 9 | CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation | Pharmacogenetics and Genomics | 2004 | 182 |
| 10 | Creatinine Transport by Basolateral Organic Cation Transporter hOCT2 in the Human Kidney | Pharmaceutical Research | 2004 | 180 |
| 11 | Renal Transport of Adefovir, Cidofovir, and Tenofovir by SLC22A Family Members (hOAT1, hOAT3, and hOCT2) | Pharmaceutical Research | 2007 | 174 |
| 12 | (Section A: Molecular, Structural, and Cellular Biology of Drug Transporters) Peptide Transporters: Structure, Function, Regulation and Application for Drug Delivery | Current Drug Metabolism | 2004 | 167 |
| 13 | Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs | Journal of Pharmacology and Experimental Therapeutics | 1998 | 165 |
| 14 | Metformin Transport by Renal Basolateral Organic Cation Transporter hOCT2 | Pharmaceutical Research | 2005 | 156 |
| 15 | Importance of the multidrug and toxin extrusion MATE/SLC47A family to pharmacokinetics, pharmacodynamics/toxicodynamics and pharmacogenomics | British Journal of Pharmacology | 2011 | 155 |
| 16 | Carrier-mediated transport systems of tetraethylammonium in rat renal brush-border and basolateral membrane vesicles | Biochimica Et Biophysica Acta - Biomembranes | 1984 | 152 |
| 17 | Gender differences in expression of organic cation transporter OCT2 in rat kidney | FEBS Letters | 1999 | 148 |
| 18 | Organic cation transporter OCT/SLC22A and H+/organic cation antiporter MATE/SLC47A are key molecules for nephrotoxicity of platinum agents | Biochemical Pharmacology | 2011 | 148 |
| 19 | Molecular cloning and tissue distribution of rat peptide transporter PEPT2 | Biochimica Et Biophysica Acta - Biomembranes | 1996 | 135 |
| 20 | Physiological and pharmacokinetic roles of H+/organic cation antiporters (MATE/SLC47A) | Biochemical Pharmacology | 2008 | 131 |
| 21 | Hormonal regulation of organic cation transporter OCT2 expression in rat kidney | FEBS Letters | 2000 | 125 |
| 22 | Cerebrospinal Fluid Concentration of Erlotinib and its Active Metabolite OSI-420 in Patients with Central Nervous System Metastases of Non-small Cell Lung Cancer | Journal of Thoracic Oncology | 2010 | 125 |
| 23 | Novel riboflavin transporter family RFVT/SLC52: Identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52 | Molecular Aspects of Medicine | 2013 | 125 |
| 24 | Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney | FEBS Letters | 1998 | 124 |
| 25 | SLCO4C1 Transporter Eliminates Uremic Toxins and Attenuates Hypertension and Renal Inflammation | Journal of the American Society of Nephrology: JASN | 2009 | 124 |
| 26 | Pharmacokinetic and prognostic significance of intestinal MDR1 expression in recipients of living-donor liver transplantation | Clinical Pharmacology and Therapeutics | 2001 | 120 |
| 27 | cDNA Cloning, Functional Characterization, and Tissue Distribution of an Alternatively Spliced Variant of Organic Cation Transporter hOCT2 Predominantly Expressed in the Human Kidney | Journal of the American Society of Nephrology: JASN | 2002 | 114 |
| 28 | Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1 | Biochemical Pharmacology | 2005 | 114 |
| 29 | Long‐term effect of tacrolimus therapy in patients with refractory ulcerative colitis | Alimentary Pharmacology and Therapeutics | 2008 | 107 |
| 30 | Peptide transporter in the rat small intestine: ultrastructural localization and the effect of starvation and administration of amino acids | The Histochemical Journal | 1999 | 103 |
| 31 | Cloning and functional characterization of a new multispecific organic anion transporter, OAT-K2, in rat kidney | Molecular Pharmacology | 1999 | 102 |
| 32 | INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph+ leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity | Blood | 2007 | 100 |
| 33 | The Diurnal Rhythm of the Intestinal Transporters SGLT1 and PEPT1 Is Regulated by the Feeding Conditions in Rats | Journal of Nutrition | 2004 | 99 |
| 34 | Expression Levels of Renal Organic Anion Transporters (OATs) and Their Correlation with Anionic Drug Excretion in Patients with Renal Diseases | Pharmaceutical Research | 2004 | 95 |
| 35 | Diurnal rhythm of H+-peptide cotransporter in rat small intestine | American Journal of Physiology - Renal Physiology | 2002 | 94 |
| 36 | Population pharmacokinetic and pharmacogenomic analysis of tacrolimus in pediatric living-donor liver transplant recipients | Clinical Pharmacology and Therapeutics | 2006 | 93 |
| 37 | Structural requirements for determining the substrate affinity of peptide transporters PEPT1 and PEPT2 | Pflugers Archiv European Journal of Physiology | 2000 | 91 |
| 38 | UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients | International Journal of Clinical Oncology | 2009 | 90 |
| 39 | Population pharmacokinetics of tacrolimus in adult recipients receiving living-donor liver transplantation | European Journal of Clinical Pharmacology | 2001 | 89 |
| 40 | Interaction and transport of thiazide diuretics, loop diuretics, and acetazolamide via rat renal organic anion transporter rOAT1 | Journal of Pharmacology and Experimental Therapeutics | 2000 | 87 |
| 41 | Methotrexate-Loxoprofen Interaction: Involvement of Human Organic Anion Transporters hOAT1 and hOAT3 | Drug Metabolism and Pharmacokinetics | 2004 | 86 |
| 42 | P-glycoprotein-mediated transcellular transport of MDR-reversing agents | FEBS Letters | 1993 | 83 |
| 43 | Identification of the histidine residues involved in substrate recognition by a rat H+/peptide cotransporter, PEPT1 | FEBS Letters | 1996 | 81 |
| 44 | mRNA distribution and membrane localization of the OAT‐K1 organic anion transporter in rat renal tubules | FEBS Letters | 1997 | 81 |
| 45 | Protective effect of concomitant administration of imatinib on cisplatin-induced nephrotoxicity focusing on renal organic cation transporter OCT2 | Biochemical Pharmacology | 2009 | 79 |
| 46 | Intestinal Absorption of Drugs Mediated by Drug Transporters: Mechanisms and Regulation | Drug Metabolism and Pharmacokinetics | 2003 | 78 |
| 47 | Population Pharmacokinetics/Pharmacodynamics of Erlotinib and Pharmacogenomic Analysis of Plasma and Cerebrospinal Fluid Drug Concentrations in Japanese Patients with Non-Small Cell Lung Cancer | Clinical Pharmacokinetics | 2013 | 77 |
| 48 | Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes | Biochimica Et Biophysica Acta - Biomembranes | 1999 | 76 |
| 49 | Efficacy of increased-dose erlotinib for central nervous system metastases in non-small cell lung cancer patients with epidermal growth factor receptor mutation | Cancer Chemotherapy and Pharmacology | 2011 | 76 |
| 50 | H+ gradient-dependent transport of aminocephalosporins in rat intestinal brush-border membrane vesicles | Biochemical Pharmacology | 1986 | 75 |
