Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer | Nature Genetics | 2001 | 807 |
Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence | Nature Cell Biology | 2006 | 426 |
Conditional mouse models of sporadic cancer | Nature Reviews Cancer | 2002 | 242 |
Assessment of 2q23.1 microdeletion syndrome implicates MBD5 as a single causal locus of intellectual disability, epilepsy, and autism spectrum disorder | American Journal of Human Genetics | 2011 | 166 |
AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity | EMBO Journal | 2007 | 144 |
Connexin-43 interactions with ZO-1 and alpha- and beta-tubulin | Cell Communication and Adhesion | 2001 | 109 |
The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots | Plant Cell | 2016 | 81 |
The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study | Neurology | 2013 | 56 |
Genetic variants associated with myocardial infarction risk factors in over 8000 individuals from five ethnic groups: The INTERHEART Genetics Study | Circulation: Cardiovascular Genetics | 2009 | 54 |
IRREGULAR POLLEN EXINE1 Is a Novel Factor in Anther Cuticle and Pollen Exine Formation | Plant Physiology | 2017 | 43 |
Genetic and phenotypic dissection of 1q43q44 microdeletion syndrome and neurodevelopmental phenotypes associated with mutations in ZBTB18 and HNRNPU | Human Genetics | 2017 | 41 |
New insights into the formation and the function of lamellipodia and ruffles in mesenchymal cell migration | Cell Adhesion and Migration | 2018 | 39 |
IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation | Nature Communications | 2016 | 38 |
Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk | Human Molecular Genetics | 2015 | 35 |
The ENCODE project and perspectives on pathways | Genetic Epidemiology | 2014 | 31 |
Identification of human D lactate dehydrogenase deficiency | Nature Communications | 2019 | 29 |
CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages-Brief Report | Arteriosclerosis, Thrombosis, and Vascular Biology | 2017 | 23 |
Identifying dysfunctional miRNA-mRNA regulatory modules by inverse activation, cofunction, and high interconnection of target genes: a case study of glioblastoma | Neuro-Oncology | 2013 | 22 |
Significant Association Between CAV1 Variant rs3807989 on 7p31 and Atrial Fibrillation in a Chinese Han Population | Journal of the American Heart Association | 2015 | 21 |
VAV3 mediates resistance to breast cancer endocrine therapy | Breast Cancer Research | 2014 | 21 |
Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers | Breast Cancer Research | 2010 | 21 |
Immune response in lung cancer mouse model mimics human anti-Hu reactivity | Journal of Neuroimmunology | 2009 | 21 |
Cancer genetics. Is p53 the only real tumor suppressor gene? | Current Biology | 1994 | 19 |
Common and Rare Genetic Variation in CCR2, CCR5, or CX3CR1 and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic Traits | Circulation: Cardiovascular Genetics | 2016 | 14 |
Aberrant Hypermethylation at Sites -86 to 226 of DAB2 Gene in Non-Small Cell Lung Cancer | American Journal of the Medical Sciences | 2015 | 12 |