| # | Title | Journal | Year | Citations |
|---|
| 1 | IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel | Journal of Experimental Medicine | 2005 | 1,998 |
| 2 | Cellular senescence mediates fibrotic pulmonary disease | Nature Communications | 2017 | 1,008 |
| 3 | Genome partitioning of genetic variation for complex traits using common SNPs | Nature Genetics | 2011 | 834 |
| 4 | The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies | Journal of Hepatology | 2005 | 819 |
| 5 | American College of Medical Genetics standards and guidelines for interpretation and reporting of postnatal constitutional copy number variants | Genetics in Medicine | 2011 | 794 |
| 6 | Genetics of adult glioma | Cancer Genetics | 2012 | 737 |
| 7 | Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2 | Molecular Cell | 2006 | 724 |
| 8 | National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for Use of Tumor Markers in Testicular, Prostate, Colorectal, Breast, and Ovarian Cancers | Clinical Chemistry | 2008 | 539 |
| 9 | The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen | Breast Cancer Research and Treatment | 2007 | 520 |
| 10 | The Clinical Phenotype of Lynch Syndrome Due to Germ-Line PMS2 Mutations | Gastroenterology | 2008 | 480 |
| 11 | Pathogenic potential of IgG binding to water channel extracellular domain in neuromyelitis optica | Neurology | 2007 | 442 |
| 12 | Incidence, Prevalence, and Clinical Course of Idiopathic Pulmonary Fibrosis | Chest | 2010 | 420 |
| 13 | Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange | Lancet, The | 2005 | 411 |
| 14 | PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata | Cancer | 2007 | 392 |
| 15 | Microbiologic Diagnosis of Prosthetic Shoulder Infection by Use of Implant Sonication | Journal of Clinical Microbiology | 2009 | 383 |
| 16 | An evidence-based approach to establish the functional and clinical significance of copy number variants in intellectual and developmental disabilities | Genetics in Medicine | 2011 | 371 |
| 17 | Fresh-Frozen Plasma and Platelet Transfusions Are Associated With Development of Acute Lung Injury in Critically Ill Medical Patients | Chest | 2007 | 346 |
| 18 | A Comparison of Routine Cytology and Fluorescence in situ Hybridization for the Detection of Malignant Bile Duct Strictures | American Journal of Gastroenterology | 2004 | 338 |
| 19 | Overview of Changes to the Clinical and Laboratory Standards Institute Performance Standards for Antimicrobial Susceptibility Testing, M100, 31st Edition | Journal of Clinical Microbiology | 2021 | 336 |
| 20 | Malignant Melanoma in the 21st Century, Part 1: Epidemiology, Risk Factors, Screening, Prevention, and Diagnosis | Mayo Clinic Proceedings | 2007 | 331 |
| 21 | Aquaporin-4–binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2 | Journal of Experimental Medicine | 2008 | 330 |
| 22 | Utility of serum tumor markers, imaging, and biliary cytology for detecting cholangiocarcinoma in primary sclerosing cholangitis | Hepatology | 2008 | 329 |
| 23 | A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24 | Nature Genetics | 2010 | 321 |
| 24 | Advanced Cytologic Techniques for the Detection of Malignant Pancreatobiliary Strictures | Gastroenterology | 2006 | 297 |
| 25 | Malignant Melanoma in the 21st Century, Part 1: Epidemiology, Risk Factors, Screening, Prevention, and Diagnosis | Mayo Clinic Proceedings | 2007 | 291 |
| 26 | From Clinical Microbiology to Infection Pathogenesis: How Daring To Be Different Works forStaphylococcus lugdunensis | Clinical Microbiology Reviews | 2008 | 284 |
| 27 | Effects of Age and Sex on Postprandial Glucose Metabolism: Differences in Glucose Turnover, Insulin Secretion, Insulin Action, and Hepatic Insulin Extraction | Diabetes | 2006 | 271 |
| 28 | The Prevalence of BRCA2 Mutations in Familial Pancreatic Cancer | Cancer Epidemiology Biomarkers and Prevention | 2007 | 255 |
| 29 | Symptoms Have Modest Accuracy in Detecting Endoscopic and Histologic Remission in Adults With Eosinophilic Esophagitis | Gastroenterology | 2016 | 251 |
| 30 | Absolute Quantification of the Model Biomarker Prostate-Specific Antigen in Serum by LC−MS/MS Using Protein Cleavage and Isotope Dilution Mass Spectrometry | Journal of Proteome Research | 2004 | 245 |
| 31 | Diagnostic Performance of Quantitative κ and λ Free Light Chain Assays in Clinical Practice | Clinical Chemistry | 2005 | 244 |
| 32 | Clinical, Radiologic, and Prognostic Features of Myelitis Associated With Myelin Oligodendrocyte Glycoprotein Autoantibody | JAMA Neurology | 2019 | 243 |
| 33 | Common variants at 19p13 are associated with susceptibility to ovarian cancer | Nature Genetics | 2010 | 235 |
| 34 | Rescue and propagation of fully retargeted oncolytic measles viruses | Nature Biotechnology | 2005 | 234 |
| 35 | Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT–mTORC1 activation | Nature Medicine | 2017 | 225 |
| 36 | Genetic variants and risk of lung cancer in never smokers: a genome-wide association study | Lancet Oncology, The | 2010 | 218 |
| 37 | Clinical Staging and Survival in Refractory Celiac Disease: A Single Center Experience | Gastroenterology | 2009 | 216 |
| 38 | Systemic Histoplasmosis | Medicine (United States) | 2007 | 215 |
| 39 | Glutamic Acid Decarboxylase Autoimmunity With Brainstem, Extrapyramidal, and Spinal Cord Dysfunction | Mayo Clinic Proceedings | 2006 | 212 |
| 40 | Extradigital Glomus Tumors: A 20-Year Experience | Mayo Clinic Proceedings | 2006 | 211 |
| 41 | Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma | Human Pathology | 2012 | 211 |
| 42 | The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas | Science | 2016 | 211 |
| 43 | MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps | Gastroenterology | 2004 | 209 |
| 44 | Improved Specificity of Newborn Screening for Congenital Adrenal Hyperplasia by Second-Tier Steroid Profiling Using Tandem Mass Spectrometry | Clinical Chemistry | 2004 | 207 |
| 45 | Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis | Cancer Cell | 2005 | 202 |
| 46 | Plasma exchange and glucocorticoid dosing in the treatment of anti-neutrophil cytoplasm antibody associated vasculitis (PEXIVAS): protocol for a randomized controlled trial | Trials | 2013 | 198 |
| 47 | Common fragile sites, extremely large genes, neural development and cancer | Cancer Letters | 2006 | 192 |
| 48 | Distinctive clinical phenotype and treatment outcome of type 1 autoimmune hepatitis in the elderly | Hepatology | 2006 | 186 |
| 49 | Pulmonary Complications in Adult Blood and Marrow Transplant Recipients | Chest | 2005 | 183 |
| 50 | Association Between Lipoprotein-Associated Phospholipase A2 and Cardiovascular Disease: A Systematic Review | Mayo Clinic Proceedings | 2007 | 182 |
