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Top Articles

#TitleJournalYearCitations
1Functional impact of global rare copy number variation in autism spectrum disordersNature20101,803
2Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated MacrophagesCell Metabolism2015887
3A genome-wide scan for common alleles affecting risk for autismHuman Molecular Genetics2010538
4Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult malesPhysiology and Behavior2011404
5Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrilsNature Chemical Biology2012400
6Individual common variants exert weak effects on the risk for autism spectrum disordersHuman Molecular Genetics2012334
7Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolismNature Immunology2016295
8Impact of Lipids on Cardiovascular HealthJournal of the American College of Cardiology2018272
9Effects of Folate and Vitamin B12 Deficiencies During Pregnancy on Fetal, Infant, and Child DevelopmentFood and Nutrition Bulletin2008245
10The effects of forced exercise on hippocampal plasticity in the rat: A comparison of LTP, spatial- and non-spatial learningBehavioural Brain Research2007230
11The structure of psychopathology in adolescence and its common personality and cognitive correlates.Journal of Abnormal Psychology2016217
12Precision Medicine in Diabetes: A Consensus Report From the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)Diabetes Care2020204
13Persistent Poor Health after COVID-19 Is Not Associated with Respiratory Complications or Initial Disease SeverityAnnals of the American Thoracic Society2021202
14The IG-DMR and the MEG3-DMR at Human Chromosome 14q32.2: Hierarchical Interaction and Distinct Functional Properties as Imprinting Control CentersPLoS Genetics2010185
15A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorderHuman Genetics2012180
16Altered structural brain asymmetry in autism spectrum disorder in a study of 54 datasetsNature Communications2019167
17Vitamin D Deficiency Is Associated With Inflammation in Older Irish AdultsJournal of Clinical Endocrinology and Metabolism2014163
18Objective Assessment of Adherence to Inhalers by Patients with Chronic Obstructive Pulmonary DiseaseAmerican Journal of Respiratory and Critical Care Medicine2017162
19Population red blood cell folate concentrations for prevention of neural tube defects: bayesian modelBMJ, The2014153
20Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular DiseaseJAMA - Journal of the American Medical Association2019144
21Medicinal plants used by traditional medicine practitioners for the treatment of HIV/AIDS and related conditions in UgandaJournal of Ethnopharmacology2010121
22Emerging role of hydrogen sulfide in colonic physiology and pathophysiologyInflammatory Bowel Diseases2011114
23Bacterial self-defence: howEscherichia colievades serum killingFEMS Microbiology Letters2014112
24Silver nanoparticles as a medical device in healthcare settings: a five-step approach for candidate screening of coating agentsRoyal Society Open Science2018110
25The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice culturesJournal of Neuroinflammation2016105
26Precision medicine in diabetes: a Consensus Report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)Diabetologia2020102
27Lipoxin A 4 and benzo‐lipoxin A 4 attenuate experimental renal fibrosisFASEB Journal2011101
28Inhibiting neuroinflammation: The role and therapeutic potential of GABA in neuro-immune interactionsBrain, Behavior, and Immunity201699
29The role of cannabinoids in adult neurogenesisBritish Journal of Pharmacology201598
30Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21Cell Reports202097
31Coevolution with Bacteriophages Drives Genome-Wide Host Evolution and Constrains the Acquisition of Abiotic-Beneficial MutationsMolecular Biology and Evolution201594
32Sphingosine-1-phosphate receptor therapies: Advances in clinical trials for CNS-related diseasesNeuropharmacology201793
33Highly Sensitive Single Domain Antibody–Quantum Dot Conjugates for Detection of HER2 Biomarker in Lung and Breast Cancer CellsACS Nano201489
34Exercise therapy for spondyloarthritis: a systematic reviewRheumatology International201487
35Common variant at 16p11.2 conferring risk of psychosisMolecular Psychiatry201485
36Radiation Oncology Safety Information System (ROSIS) – Profiles of participants and the first 1074 incident reportsRadiotherapy and Oncology201083
37Sláintecare – A ten-year plan to achieve universal healthcare in IrelandHealth Policy201883
38Indicators of health system coverage and activity in Ireland during the economic crisis 2008–2014 – From ‘more with less’ to ‘less with less’Health Policy201475
39Noradrenaline acting at β-adrenoceptors induces expression of IL-1β and its negative regulators IL-1ra and IL-1RII, and drives an overall anti-inflammatory phenotype in rat cortexNeuropharmacology201072
40Priorities for the global advancement of care for older adults with cancer: an update of the International Society of Geriatric Oncology Priorities InitiativeLancet Oncology, The202171
41Popliteal aneurysms: a 10-year experienceEuropean Journal of Vascular and Endovascular Surgery199870
42MicroRNA-497 increases apoptosis in MYCN amplified neuroblastoma cells by targeting the key cell cycle regulator WEE1Molecular Cancer201368
43Innate gene repression associated with Mycobacterium bovis infection in cattle: toward a gene signature of diseaseBMC Genomics200765
44Elucidating the role of carbohydrate determinants in regulating hemostasis: insights and opportunitiesBlood201363
45The Impact of Increased Duration of Exercise Therapy on Functional Recovery Following Stroke — What Is the Evidence?Topics in Stroke Rehabilitation200861
46Upregulation of Retinal Dehydrogenase 2 in Alternatively Activated Macrophages during Retinoid-dependent Type-2 Immunity to Helminth Infection in MicePLoS Pathogens201261
47Bimodal neuromodulation combining sound and tongue stimulation reduces tinnitus symptoms in a large randomized clinical studyScience Translational Medicine202061
48Lipopolysaccharide impairs long-term potentiation and recognition memory and increases p75NTR expression in the rat dentate gyrusBrain Research200760
49An investigation of children's posture and discomfort during computer useErgonomics200759
50Common variants in genes of the postsynaptic FMRP signalling pathway are risk factors for autism spectrum disordersHuman Genetics201459