| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | A new framework for developing and evaluating complex interventions: update of Medical Research Council guidance | BMJ, The | 2021 | 1,567 |
| 3 | The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis | Lancet Psychiatry,the | 2017 | 459 |
| 4 | Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage | Molecular Cell | 2018 | 417 |
| 5 | Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology | Brain | 2016 | 389 |
| 6 | Systematic review and meta-analysis of enhanced recovery programmes in surgical patients | British Journal of Surgery | 2014 | 351 |
| 7 | TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys | Cell Metabolism | 2013 | 340 |
| 8 | Efficacy of contact tracing for the containment of the 2019 novel coronavirus (COVID-19) | Journal of Epidemiology and Community Health | 2020 | 245 |
| 9 | PrimPol Bypasses UV Photoproducts during Eukaryotic Chromosomal DNA Replication | Molecular Cell | 2013 | 235 |
| 10 | Updated unified phylogenetic classification system and revised nomenclature for Newcastle disease virus | Infection, Genetics and Evolution | 2019 | 227 |
| 11 | Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases | Journal of Endocrinology | 2014 | 224 |
| 12 | Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer’s disease and down syndrome | Molecular Neurodegeneration | 2017 | 202 |
| 13 | The Relationship Between Online Social Networking and Depression: A Systematic Review of Quantitative Studies | Cyberpsychology, Behavior, and Social Networking | 2016 | 188 |
| 14 | Non-invasive brain stimulation techniques for chronic pain | The Cochrane Library | 2014 | 185 |
| 15 | Framework for the development and evaluation of complex interventions: gap analysis, workshop and consultation-informed update | Health Technology Assessment | 2021 | 184 |
| 16 | The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non‐human primate model of Alzheimer's disease | Journal of Pathology | 2018 | 180 |
| 17 | Molecular paleontology and complexity in the last eukaryotic common ancestor | Critical Reviews in Biochemistry and Molecular Biology | 2013 | 170 |
| 18 | Enteroendocrine cells-sensory sentinels of the intestinal environment and orchestrators of mucosal immunity | Mucosal Immunology | 2018 | 163 |
| 19 | Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease | Neuroscience | 2015 | 162 |
| 20 | Therapeutic mobilities: walking and ‘steps’ to wellbeing and health | Health and Place | 2013 | 150 |
| 21 | Values associated with public involvement in health and social care research: a narrative review | Health Expectations | 2015 | 132 |
| 22 | Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer's disease | Neuropharmacology | 2014 | 130 |
| 23 | Neuroprotective and anti‐apoptotic effects of liraglutide on SH‐SY5Y cells exposed to methylglyoxal stress | Journal of Neurochemistry | 2014 | 129 |
| 24 | Liposome delivery systems for the treatment of Alzheimer’s disease | International Journal of Nanomedicine | 2018 | 127 |
| 25 | Novel dual GLP-1/GIP receptor agonists show neuroprotective effects in Alzheimer's and Parkinson's disease models | Neuropharmacology | 2018 | 126 |
| 26 | Differential diagnosis of Alzheimer’s disease using spectrochemical analysis of blood | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 125 |
| 27 | Emotional intelligence in medical education: a critical review | Medical Education | 2014 | 124 |
| 28 | Case management approaches to home support for people with dementia | The Cochrane Library | 2015 | 123 |
| 29 | The geographic distribution of onchocerciasis in the 20 participating countries of the African Programme for Onchocerciasis Control: (2) pre-control endemicity levels and estimated number infected | Parasites and Vectors | 2014 | 120 |
| 30 | The SKN‐1/Nrf2 transcription factor can protect against oxidative stress and increase lifespan in C. elegans by distinct mechanisms | Aging Cell | 2017 | 115 |
| 31 | Family carers providing support to a person dying in the home setting: A narrative literature review | Palliative Medicine | 2015 | 113 |
| 32 | The impact of chemotherapy-related nausea on patients' nutritional status, psychological distress and quality of life | Supportive Care in Cancer | 2013 | 111 |
| 33 | Hierarchical patterning modes orchestrate hair follicle morphogenesis | PLoS Biology | 2017 | 109 |
| 34 | Blood–Brain Barrier Leakage Is Increased in Parkinson’s Disease | Frontiers in Physiology | 2020 | 107 |
| 35 | Sequence-independent characterization of viruses based on the pattern of viral small RNAs produced by the host | Nucleic Acids Research | 2015 | 104 |
| 36 | Nonsteroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy | The Cochrane Library | 2013 | 102 |
| 37 | Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration | Nature Cell Biology | 2019 | 102 |
| 38 | Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells | Cell Stem Cell | 2019 | 97 |
| 39 | Standardization of complex biologically derived spectrochemical datasets | Nature Protocols | 2019 | 96 |
| 40 | A rapid review of the use of face mask in preventing the spread of COVID-19 | International Journal of Nursing Studies Advances | 2021 | 96 |
| 41 | Evolution of cardiorespiratory interactions with age | Philosophical Transactions Series A, Mathematical, Physical, and Engineering Sciences | 2013 | 95 |
| 42 | Prophylactic liraglutide treatment prevents amyloid plaque deposition, chronic inflammation and memory impairment in APP/PS1 mice | Behavioural Brain Research | 2015 | 94 |
| 43 | β-Amyloid Fibrils in Alzheimer Disease Are Not Inert When Bound to Copper Ions but Can Degrade Hydrogen Peroxide and Generate Reactive Oxygen Species | Journal of Biological Chemistry | 2014 | 93 |
| 44 | Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK | BMJ Open | 2015 | 92 |
| 45 | Recovery-focused cognitive–behavioural therapy for recent-onset bipolar disorder: Randomised controlled pilot trial | British Journal of Psychiatry | 2015 | 92 |
| 46 | Insulin, incretins and other growth factors as potential novel treatments for Alzheimer's and Parkinson's diseases | Biochemical Society Transactions | 2014 | 91 |
| 47 | Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection | Parasites and Vectors | 2014 | 91 |
| 48 | Reactive Oxygen Species-mediated Immunity against Leishmania mexicana and Serratia marcescens in the Phlebotomine Sand Fly Lutzomyia longipalpis | Journal of Biological Chemistry | 2012 | 87 |
| 49 | Evaluation of public health interventions from a complex systems perspective: A research methods review | Social Science and Medicine | 2021 | 86 |
| 50 | Factors affecting implementation of digital health interventions for people with psychosis or bipolar disorder, and their family and friends: a systematic review | Lancet Psychiatry,the | 2019 | 85 |
