Hot regions in protein--protein interactions: the organization and contribution of structurally conserved hot spot residues | Journal of Molecular Biology | 2005 | 394 |
PRISM: protein interactions by structural matching | Nucleic Acids Research | 2005 | 167 |
Geometry-based flexible and symmetric protein docking | Proteins: Structure, Function and Bioinformatics | 2005 | 155 |
Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 145 |
Differentiation of human liver-derived, insulin-producing cells toward the beta-cell phenotype | Diabetes | 2005 | 141 |
Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling | Journal of Biological Chemistry | 2005 | 123 |
Apolipoprotein E4 enhances brain inflammation by modulation of the NF-kappaB signaling cascade | Neurobiology of Disease | 2005 | 115 |
ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation | Cell Cycle | 2005 | 115 |
DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation | Molecular and Cellular Biology | 2005 | 107 |
Energy landscape of amyloidogenic peptide oligomerization by parallel-tempering molecular dynamics simulation: significant role of Asn ladder | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 106 |
Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education | Pharmacogenomics Journal | 2005 | 100 |
PKC-delta-dependent activation of oxidative stress in adipocytes of obese and insulin-resistant mice: role for NADPH oxidase | American Journal of Physiology - Endocrinology and Metabolism | 2005 | 90 |
Accurate identification of alternatively spliced exons using support vector machine | Bioinformatics | 2005 | 89 |
Protein-protein interactions: organization, cooperativity and mapping in a bottom-up Systems Biology approach | Physical Biology | 2005 | 84 |
Human-mouse comparative analysis reveals that branch-site plasticity contributes to splicing regulation | Human Molecular Genetics | 2005 | 81 |
Genetic dissection of Pax6 dosage requirements in the developing mouse eye | Human Molecular Genetics | 2005 | 68 |
A comparative study of amyloid fibril formation by residues 15-19 of the human calcitonin hormone: a single beta-sheet model with a small hydrophobic core | Journal of Molecular Biology | 2005 | 67 |
Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis | Genome Biology | 2005 | 62 |
Signaling through FGF receptor-2 is required for lens cell survival and for withdrawal from the cell cycle during lens fiber cell differentiation | Developmental Dynamics | 2005 | 62 |
How similar are protein folding and protein binding nuclei? Examination of vibrational motions of energy hot spots and conserved residues | Biophysical Journal | 2005 | 60 |
Favorable scaffolds: proteins with different sequence, structure and function may associate in similar ways | Protein Engineering, Design and Selection | 2005 | 57 |
The importance of being divisible by three in alternative splicing | Nucleic Acids Research | 2005 | 51 |
Stress alters the subcellular distribution of hSlu7 and thus modulates alternative splicing | Journal of Cell Science | 2005 | 47 |
Generation and analysis of a protein-protein interface data set with similar chemical and spatial patterns of interactions | Proteins: Structure, Function and Bioinformatics | 2005 | 40 |
Overexpression of calpastatin inhibits L8 myoblast fusion | Biochemical and Biophysical Research Communications | 2005 | 39 |